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Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology

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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Bos d 5

Translate to AllerML
AllergenBos d 5
Typefoods
Species - Systematic NameBos domesticus
Species - Common Namedomestic cattle
Keywordsbeta-lactoglobulin; Beta-LG
ClassIUIS

Bos d 5 - PubMedReference
Reference 1Alexander LJ, Hayes G, Pearse MJ, Beattie CW, Stewart AF, Willis IM, Mackinlay AG. Complete sequence of the bovine beta-lactoglobulin cDNA. Nucleic Acids Res. 1989 Aug 25;17(16):6739.
Reference 2Braunitzer G, Chen R, Schrank B, Stangl A. [The sequence of beta-lactoglobulin (author's transl)] Hoppe Seylers Z Physiol Chem. 1973 Aug;354(8):867-78. German.
Reference 3Jamieson AC, Vandeyar MA, Kang YC, Kinsella JE, Batt CA. Cloning and nucleotide sequence of the bovine beta-lactoglobulin gene. Gene. 1987;61(1):85-90.
Reference 4McKenzie HA, Ralston GB, Shaw DC. Location of sulfhydryl and disulfide groups in bovine -lactoglobulins and effects of urea. Biochemistry. 1972 Nov 21;11(24):4539-47.
Reference 5Godovac-Zimmermann J, Krause I, Buchberger J, Weiss G, Klostermeyer H. Genetic variants of bovine beta-lactoglobulin. A novel wild-type beta-lactoglobulin W and its primary sequence. Biol Chem Hoppe Seyler. 1990 Mar;371(3):255-60.
Reference 6Monaco HL, Zanotti G. Three-dimensional structure and active site of three hydrophobic molecule-binding proteins with significant amino acid sequence similarity. Biopolymers. 1992 Apr;32(4):457-65.
Reference 7Kuwata K, Hoshino M, Forge V, Era S, Batt CA, Goto Y. Solution structure and dynamics of bovine beta-lactoglobulin A. Protein Sci. 1999 Nov;8(11):2541-5.

Bos d 5 - Protein Sequences
SourceLink to SourceView SequenceFASTA@SDAPBLAST@NCBIBLAST@ExPASyPROSITE@PIR
SwissProtP02754Go!Go!Go!Go!Go!
GenBank520Go!Go!Go!Go!Go!
GenBank162750Go!Go!Go!Go!Go!
GenBank162748Go!Go!Go!Go!Go!
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Bos d 5 - Protein Sequence Properties
Protein SequenceProtease cleavage sites
PeptideCutter@ExPASy
P02754Go!
520Go!
162750Go!
162748Go!
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Bos d 5 - Protein Similarity, Classification and Clustering
Protein SequenceSuperfamilyInterPro
P02754Go!Go!

Bos d 5 - Protein Models
3D ModelSourceLink to SourceView SequenceView AlignmentGet ModelPicturePicture+90Picture+180Picture+270Jmol
Model 563GenBank162748Go!Go!Go!Go!Go!Go!Go!View!


Bos d 5 - Pfam domains
SequencePfam sequencePfam familyAllergens from
this Pfam family
Pfam databasePfam regionFirst amino acidLast amino acid
P02754       
 LACB_BOVINPF00061Go!Pfam A132173
  PF00061: Lipocalin / cytosolic fatty-acid binding protein family
520       
 LACB_BOVINPF00061Go!Pfam A132173
  PF00061: Lipocalin / cytosolic fatty-acid binding protein family
162748       
  PF00061Go!Pfam A15146
Pfam is a database of multiple sequence alignments and hidden Markov models covering protein domains and families

Inspect MotifMate results for Bos d 5. AutoMotif contains a database of PCPMer motifs for allergens.
MotifMate home page
MotifMate summary
Browse MotifMate proteins
Browse MotifMate families

Bos d 5 - Sequences from the Entrez Nucleotides database
Link to GenBankView Sequence
519Go!

Bos d 5 - PDB Structures
PDB AccessionJmolDeposition dateExperimentalObservation
1BEBView!20-DEC-96X-ray diffraction resolution 1.8 A 
1BSOView!29-AUG-98X-ray diffraction resolution 2.23 A 
1BSQView!29-AUG-98X-ray diffraction resolution 2.22 A 
1BSYView!31-AUG-98X-ray diffraction resolution 2.24 A 
2BLGView!29-AUG-98X-ray diffraction resolution 2.46 A 
3BLGView!29-AUG-98X-ray diffraction resolution 2.56 A 
1B0OView!11-NOV-98X-ray diffraction resolution 2.50 Acomplex with palmitic acid
1CJ5View!22-APR-99NMR, 10 structuresmutant
1GX8View!29-MAR-02X-ray diffraction resolution 2.4 Acomplexed with retinol
1GX9View!29-MAR-02X-ray diffraction resolution 2.34 Acomplexed with retinoic acid
1GXAView!01-APR-02X-ray diffraction resolution 2.35 Acomplexed with palmitic acid
1UZ2View!03-MAR-04X-ray diffraction resolution 1.95 A 
2Q2PView!2007-05-29X-ray diffraction resolution 2.96 A 
2Q39View!2007-05-30X-ray diffraction resolution 2.50 A 
2AKQView!2005-08-03X-ray diffraction resolution 3.00 Astructure of bovine beta-lactoglobulin at very low ionic strength
2GJ5View!2006-03-30X-ray diffraction resolution 2.40 Acomplex with vitamin D3
2Q2MView!2007-05-29X-ray diffraction resolution 2.10 A 
2R56View!2007-09-03X-ray diffraction resolution 2.80 Acomplex with IgE (heavy and light chains)


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