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SDAP - All Allergens

Go to: SDAP All allergens		Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc		Submit new allergen information to SDAP
Last Updated: Nov 1, 2021
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use. Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Alt a 1

Translate to AllerML

Allergen	Alt a 1
Type	fungi (moulds)
Species - Systematic Name	Ascomycota Dothidiales; Alternaria alternata
Species - Common Name
Keywords	N
Class	IUIS

Alt a 1 - PubMed	Reference
Reference 1	Kurup VP, Vijay HM, Kumar V, Castillo L, Elms N, IgE binding synthetic peptides of Alt a 1, a major allergen of Alternaria alternata. Peptides. 2003 Feb;24(2):179-85.
Reference 2	Rosenthal D, Hu F, Pacheco F, Landuyt J, Barnes C, Portnoy J, Northern blot identification of mRNA containing sequence for protein allergen, Alt a1, in eight strains of Alternaria alternata. Ann Allergy Asthma Immunol. 1998 Jun;80(6):471-5.
Reference 3	De Vouge MW, Thaker AJ, Curran IH, Zhang L, Muradia G, Rode H, Vijay HM, Isolation and expression of a cDNA clone encoding an Alternaria alternata Alt a 1 subunit. Int Arch Allergy Immunol. 1996 Dec;111(4):385-95.
Reference 4	Zhang L, Curran IH, Muradia G, De Vouge MW, Rode H, Vijay HM, N-terminus of a major allergen, Alt a I, of Alternaria alternata defined to be an epitope. Int Arch Allergy Immunol. 1995 Nov;108(3):254-9.

Alt a 1 - Isoallergens

No	Isoallergen
1	Alt a 1.0101
2	Alt a 1.0102

Alt a 1 - Protein Sequences

Source	Link to Source	View Sequence	FASTA@SDAP	BLAST@NCBI	BLAST@ExPASy	PROSITE@PIR
SwissProt	P79085	Go!	Go!	Go!	Go!	Go!

FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Alt a 1 - Protein Sequence Properties

Protein Sequence	Protease cleavage sites PeptideCutter@ExPASy
P79085	Go!

PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Alt a 1 - Protein Similarity, Classification and Clustering

Protein Sequence	Superfamily	InterPro
P79085	Go!	Go!

Alt a 1 - Sequences from the Entrez Nucleotides database

Link to GenBank	View Sequence
1773368	Go!

Alt a 1 - PDB Structures

PDB Accession	Jmol	Deposition date	Experimental	Observation
3V0R	View!	2011-12-08	X-ray diffraction resolution 1.90 A	crystal structure of Alternaria alternata allergen Alt a 1

Alt a 1 - Epitopes

No	Epitope	Exact Match @SDAP	Peptide Similarity @SDAP	Exact Match @PIR	Position	Type	Description
1	KISEFYGRKP	Go!	Go!	Go!	41-50	IgE
2	YYNSLGFNIK	Go!	Go!	Go!	54-63	IgE

V. P. Kurup, H. M. Vijay, V. Kumar, L. Castillo, and N. Elms, IgE binding synthetic peptides of Alt a 1, a major allergen of Alternaria alternata, Peptides 2003, 00, 00-00.