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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Alt a 1

Translate to AllerML
AllergenAlt a 1
Typefungi (moulds)
Species - Systematic NameAscomycota Dothidiales; Alternaria alternata
Species - Common Name 
KeywordsN
ClassIUIS

Alt a 1 - PubMedReference
Reference 1Kurup VP, Vijay HM, Kumar V, Castillo L, Elms N, IgE binding synthetic peptides of Alt a 1, a major allergen of Alternaria alternata. Peptides. 2003 Feb;24(2):179-85.
Reference 2Rosenthal D, Hu F, Pacheco F, Landuyt J, Barnes C, Portnoy J, Northern blot identification of mRNA containing sequence for protein allergen, Alt a1, in eight strains of Alternaria alternata. Ann Allergy Asthma Immunol. 1998 Jun;80(6):471-5.
Reference 3De Vouge MW, Thaker AJ, Curran IH, Zhang L, Muradia G, Rode H, Vijay HM, Isolation and expression of a cDNA clone encoding an Alternaria alternata Alt a 1 subunit. Int Arch Allergy Immunol. 1996 Dec;111(4):385-95.
Reference 4Zhang L, Curran IH, Muradia G, De Vouge MW, Rode H, Vijay HM, N-terminus of a major allergen, Alt a I, of Alternaria alternata defined to be an epitope. Int Arch Allergy Immunol. 1995 Nov;108(3):254-9.

Alt a 1 - Isoallergens
NoIsoallergen
1Alt a 1.0101
2Alt a 1.0102

Alt a 1 - Protein Sequences
SourceLink to SourceView SequenceFASTA@SDAPBLAST@NCBIBLAST@ExPASyPROSITE@PIR
SwissProtP79085Go!Go!Go!Go!Go!
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Alt a 1 - Protein Sequence Properties
Protein SequenceProtease cleavage sites
PeptideCutter@ExPASy
P79085Go!
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Alt a 1 - Protein Similarity, Classification and Clustering
Protein SequenceSuperfamilyInterPro
P79085Go!Go!

Alt a 1 - Sequences from the Entrez Nucleotides database
Link to GenBankView Sequence
1773368Go!

Alt a 1 - PDB Structures
PDB AccessionJmolDeposition dateExperimentalObservation
3V0RView!2011-12-08X-ray diffraction resolution 1.90 Acrystal structure of Alternaria alternata allergen Alt a 1

Alt a 1 - Epitopes
NoEpitopeExact
Match
@SDAP
Peptide
Similarity
@SDAP
Exact
Match
@PIR
PositionTypeDescription
1KISEFYGRKPGo!Go!Go!41-50IgE 
2YYNSLGFNIKGo!Go!Go!54-63IgE 
V. P. Kurup, H. M. Vijay, V. Kumar, L. Castillo, and N. Elms, IgE binding synthetic peptides of Alt a 1, a major allergen of Alternaria alternata, Peptides 2003, 00, 00-00.


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