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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Pru av 1

Translate to AllerML
AllergenPru av 1
Typefoods
Species - Systematic NamePrunus avium
Species - Common Namesweet cherry
Keywordshomolog: Bet v 1; homolog: pathogenesis related protein PR10
ClassIUIS

Pru av 1 - PubMedReference
Reference 1Reuter A, Fortunato D, Garoffo LP, Napolitano L, Scheurer S, Giuffrida MG, Vieths S, Conti A, Novel isoforms of Pru av 1 with diverging immunoglobulin E binding properties identified by a synergistic combination of molecular biology and proteomics. Proteomics. 2005 Jan;5(1):282-9.
Reference 2Gruber P, Vieths S, Wangorsch A, Nerkamp J, Hofmann T, Maillard reaction and enzymatic browning affect the allergenicity of Pru av 1, the major allergen from cherry (Prunus avium). J Agric Food Chem. 2004 Jun 16;52(12):4002-7.
Reference 3Neudecker P, Lehmann K, Nerkamp J, Haase T, Wangorsch A, Fotisch K, Hoffmann S, Rosch P, Vieths S, Scheurer S, Comment in: Biochem J. 2003 Nov 15;376(Pt 1):e1-2. Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure. Biochem J. 2003 Nov 15;376(Pt 1):97-107.
Reference 4Scheurer S, Pastorello EA, Wangorsch A, Kastner M, Haustein D, Vieths S, Recombinant allergens Pru av 1 and Pru av 4 and a newly identified lipid transfer protein in the in vitro diagnosis of cherry allergy. J Allergy Clin Immunol. 2001 Apr;107(4):724-31.
Reference 5Scheurer S, Metzner K, Haustein D, Vieths S, Molecular cloning, expression and characterization of Pru a 1, the major cherry allergen. Mol Immunol. 1997 Jun;34(8-9):619-29.

Pru av 1 - Isoallergens
NoIsoallergen
1Pru av 1.0101
2Pru av 1.0201
3Pru av 1.0202
4Pru av 1.0203

Pru av 1 - Protein Sequences
SourceLink to SourceView SequenceFASTA@SDAPBLAST@NCBIBLAST@ExPASyPROSITE@PIR
SwissProtO24248Go!Go!Go!Go!Go!
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Pru av 1 - Protein Sequence Properties
Protein SequenceProtease cleavage sites
PeptideCutter@ExPASy
O24248Go!
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Pru av 1 - Protein Similarity, Classification and Clustering
Protein SequenceSuperfamilyInterPro
O24248Go!Go!

Pru av 1 - Sequences from the Entrez Nucleotides database
Link to GenBankView Sequence
1513215Go!

Pru av 1 - PDB Structures
PDB AccessionJmolDeposition dateExperimentalObservation
1E09View!15-MAR-00NMR, 22 structures 
1H2OView!12-AUG-02NMR, 24 structuresmutation Glu45Trp


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