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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Bet v 2

Translate to AllerML
AllergenBet v 2
Typetree
Species - Systematic NameFagales; Betula verrucosa (Betula pendula)
Species - Common NameWhite birch
Keywordsprofilin
ClassIUIS

Bet v 2 - PubMedReference
Reference 1Niederberger V, Pauli G, Gronlund H, Froschl R, Rumpold H, Kraft D, Valenta R, Spitzauer S. Recombinant birch pollen allergens (rBet v 1 and rBet v 2) contain most of the IgE epitopes present in birch, alder, hornbeam, hazel, and oak pollen: a quantitative IgE inhibition study with sera from different populations. J Allergy Clin Immunol. 1998 Oct;102(4 Pt 1):579-91.
Reference 2Valenta R, Duchene M, Pettenburger K, Sillaber C, Valent P, Bettelheim P, Breitenbach M, Rumpold H, Kraft D, Scheiner O. Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals. Science. 1991 Aug 2;253(5019):557-60.
Reference 3Fedorov AA, Ball T, Mahoney NM, Valenta R, Almo SC. The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin. Structure. 1997 Jan 15;5(1):33-45.
Reference 4Fedorov AA, Ball T, Valenta R, Almo SC. X-ray crystal structures of birch pollen profilin and Phl p 2. Int Arch Allergy Immunol. 1997 May-Jul;113(1-3):109-13.
Reference 5Domke T, Federau T, Schluter K, Giehl K, Valenta R, Schomburg D, Jockusch BM. Birch pollen profilin: structural organization and interaction with poly-(L-proline) peptides as revealed by NMR. FEBS Lett. 1997 Jul 14;411(2-3):291-5.

Bet v 2 - Protein Sequences
SourceLink to SourceView SequenceFASTA@SDAPBLAST@NCBIBLAST@ExPASyPROSITE@PIR
SwissProtP25816Go!Go!Go!Go!Go!
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Bet v 2 - Protein Sequence Properties
Protein SequenceProtease cleavage sites
PeptideCutter@ExPASy
P25816Go!
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Bet v 2 - Protein Similarity, Classification and Clustering
Protein SequenceSuperfamilyInterPro
P25816Go!Go!

Bet v 2 - Sequences from the Entrez Nucleotides database
Link to GenBankView Sequence
166952Go!

Bet v 2 - PDB Structures
PDB AccessionJmolDeposition dateExperimentalObservation
1CQAView!26-JUL-96X-ray diffraction resolution 2.4 A 


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