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SDAP - All Allergens

Go to: SDAP All allergens		Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc		Submit new allergen information to SDAP
Last Updated: Nov 1, 2021
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use. Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Der p 21.0101

Sequence 85687540

Full FASTA alignment

Sequence name:
Query sequence:
MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY

No Allergen Sequence Link in
SwissProt/NCBI/PIR View Sequence Sequence
Length bit score E score
1 Der p 21.0101 ABC73706 Go! 140 204.7 7.6e-55
2 Der f 21.0101 B2GM84 Go! 136 146.0 3.6e-37
3 Lep d 5.0103 AAQ73494 Go! 169 82.6 5.2e-18
4 Lep d 5.0102 AAQ73493 Go! 171 82.6 5.3e-18
5 Lep d 5.0101 Q9U5P2 Go! 110 81.5 7.2e-18
6 Blo t 21.0101 ABH06348 Go! 129 78.0 9.6e-17
7 Blo t 21.0101 ABH06344 Go! 129 77.8 1.1e-16
8 Blo t 21.0101 ABH06347 Go! 129 77.8 1.1e-16
9 Blo t 21.0101 ABH06350 Go! 129 76.7 2.5e-16
10 Blo t 21.0101 ABH06346 Go! 129 76.7 2.5e-16
11 Blo t 5 O96870 Go! 134 76.5 2.9e-16
12 Der f 5.0101 ABO84970 Go! 132 68.2 9.1e-14
13 Der p 5.0102 P14004 Go! 132 63.0 3.3e-12
14 Der p 5.0101 CAA35692 Go! 148 63.0 3.5e-12
15 Der p 5.0102 AAB32842 Go! 132 62.6 4.4e-12

Alignment made with FASTA 3.45
As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous.

Alignment 1
Sequence 1:
Sequence 2: Allergen Der p 21.0101, Sequence: ABC73706
Sequence identity: 100.00 (140/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
Sequence 2 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
Sequence 2 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
Sequence 2 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY

Alignment 2
Sequence 1:
Sequence 2: Allergen Der f 21.0101, Sequence: B2GM84
Sequence identity: 70.00 (98/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII--F-AIVMA--VSGFIV----ED-WR-AFD---MEE-E-K-DQ-E
Sequence 2 MKFII--FCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           -GLL-LSEQYKELEKTKSKELKEQILRELTI-EN---GALKF---EAKRT
Sequence 2 HGLLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DLNMFERYN-E-A---I--L-K-L-ELAKKVKAV--D---
Sequence 2 DLNMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD--

Alignment 3
Sequence 1:
Sequence 2: Allergen Lep d 5.0103, Sequence: AAQ73494
Sequence identity: 42.14 (59/140)
Sequence 1 --------------------------------MKFIITLFAAIVMAAAVS
           --------------------------------------L--------AV-
Sequence 2 MTGVKTHLQHELKRTDLNFLEKFNLDEITAPLNVLTKELTEVQKHVKAVE

Sequence 1 GFIVGDKKEDEWRMAFDRLMMEELETKIDQVEKGLLHLSEQYKELEKTKS
           ---V-----DE-R--FDRL-----E------E--L-HLS-Q--ELEK-KS
Sequence 2 SDEVAIPNPDEFRNEFDRLLIHMTEEQFAKLEQALAHLSHQVTELEKSKS

Sequence 1 KELKEQILRELTIGENFMKGALKFFEMEAKRTDLNMFERYNYEFALESIK
           KELK-QILRE--IG--F---A---FE-E-KR-DLN--E--N-E-AL----
Sequence 2 KELKAQILREISIGLDFIDSAKGHFERELKRADLNLAEKFNFESALSTGA

Sequence 1 LLIKKLDELAKKVKAVNPDEYY
           -L-K-L--LA-KVKA-------
Sequence 2 VLHKDLTALATKVKAIETK---

Alignment 4
Sequence 1:
Sequence 2: Allergen Lep d 5.0102, Sequence: AAQ73493
Sequence identity: 42.14 (59/140)
Sequence 1 ----------------------------------MKFIITLFAAIVMAAA
           ---------------------------------------T-----V-A--
Sequence 2 MTGVKTHLEHELKRTDLNFLEKFNLDEITATLNVLTKELTEVQKHVKAVE

Sequence 1 VSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVEKGLLHLSEQYKELEKT
           -----V-----DE-R--FDRL-----E------E--L-HLS-Q--ELEK-
Sequence 2 SDEVDVAIPNPDEFRNEFDRLLIHMTEEQFAKLEQALAHLSHQVTELEKS

Sequence 1 KSKELKEQILRELTIGENFMKGALKFFEMEAKRTDLNMFERYNYEFALES
           KSKELK-QILRE--IG--F---A---FE-E-KR-DLN--E--N-E-AL--
Sequence 2 KSKELKAQILREISIGLDFIDSAKGHFERELKRADLNLAEKFNFESALST

Sequence 1 IKLLIKKLDELAKKVKAVNPDEYY
           ---L-K-L--LA-KVKA-------
Sequence 2 GAVLHKDLTALATKVKAIETK---

Alignment 5
Sequence 1:
Sequence 2: Allergen Lep d 5.0101, Sequence: Q9U5P2
Sequence identity: 38.57 (54/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           ---------------------------D--R--FDRL-----E------E
Sequence 2 ---------------------------DDFRNEFDRLLIHMTEEQFAKLE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           --L-HLS-Q--ELEK-KSKELK-QILRE--IG--F---A---FE-E-KR-
Sequence 2 QALAHLSHQVTELEKSKSKELKAQILREISIGLDFIDSAKGHFERELKRA

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DLN--E--N-E-AL-----L-K-L--LA-KVKA-------
Sequence 2 DLNLAEKFNFESALSTGAVLHKDLTALATKVKAIETK---

Alignment 6
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06348
Sequence identity: 37.86 (53/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII-L-A-I--A-A-----V-----D--R--FD--------------E
Sequence 2 MKFIIALAALIAVACALP---VSN---DNFRHEFDHMIINTATQRFHEIE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           K-LLH-------LEKT--K--K---LRELT--E-F--G----F--E-KRT
Sequence 2 KFLLHITHEVDDLEKTGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL---E--N-E-AL----LL-K-L--L-K-V---------
Sequence 2 DLDLLEKFNFEAALATGDLLLKDLKALQKRVQDSE-----

Alignment 7
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06344
Sequence identity: 37.86 (53/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII-L-A-I--A-A-----V-----D--R--FD--------------E
Sequence 2 MKFIIALAALIAVACALP---VSN---DNFRHEFDHMIVNTATQRFHEIE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           K-LLH-------LEKT--K--K---LRELT--E-F--G----F--E-KRT
Sequence 2 KFLLHITHEVDDLEKTGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL---E--N-E-AL----LL-K-L--L-K-V---------
Sequence 2 DLDLLEKFNFEAALATGDLLLKDLKALQKRVQDSE-----

Alignment 8
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06347
Sequence identity: 37.86 (53/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII-L-A-I--A-A-----V-----D--R--FD--------------E
Sequence 2 MKFIIALAALIAVACALP---VSN---DNFRHEFDHMIVNAATQRFHEIE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           K-LLH-------LEKT--K--K---LRELT--E-F--G----F--E-KRT
Sequence 2 KFLLHITHEVDDLEKTGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL---E--N-E-AL----LL-K-L--L-K-V---------
Sequence 2 DLDLLEKFNFEAALATGDLLLKDLKALQKRVQDSE-----

Alignment 9
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06350
Sequence identity: 37.14 (52/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII-L-A-I--A-A-----V-----D--R--FD--------------E
Sequence 2 MKFIIALAALIAVACALP---VSN---DNFRHEFDHMIVNTATQRFHEIE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           K-LLH-------LE-T--K--K---LRELT--E-F--G----F--E-KRT
Sequence 2 KFLLHITHEVDDLEETGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL---E--N-E-AL----LL-K-L--L-K-V---------
Sequence 2 DLDLLEKFNFEAALATGDLLLKDLKALQKRVQDSE-----

Alignment 10
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06346
Sequence identity: 37.86 (53/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII-L-A-I--A-A-----V-----D--R--FD--------------E
Sequence 2 MKFIIALAALIAVACALP---VSN---DNFRHEFDHMIVNTATQRFHEIE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           K-LLH-------LEKT--K--K---LRELT--E-F--G----F--E-KRT
Sequence 2 KFLLHITHEVDDLEKTGNKDEKARPLRELTVSEAFIEGSRGYFQRELKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL---E--N-E-AL----LL-K-L--L-K-V---------
Sequence 2 DLDLLEKFNFEAALATGDLLLKDLKALQKRVQDSE-----

Alignment 11
Sequence 1:
Sequence 2: Allergen Blo t 5, Sequence: O96870
Sequence identity: 42.14 (59/140)
Sequence 1 MKFIITL---FAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKID
           MKF-I-L---FAA-V-A-----------K-D--R--FD-L--E-----I-
Sequence 2 MKFAIVLIACFAASVLAQE------HKPKKDDFRNEFDHLLIEQANHAIE

Sequence 1 QVEKGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEA
           --E--LL-L--Q--EL---KSKEL-E-I-REL--------GA----E-E-
Sequence 2 KGEHQLLYLQHQLDELNENKSKELQEKIIRELDVVCAMIEGAQGALEREL

Sequence 1 KRTDLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           KRTDLN--ER-NYE-A----K-L-K-L-E---KVK--------
Sequence 2 KRTDLNILERFNYEEAQTLSKILLKDLKETEQKVKDIQTQ---

Alignment 12
Sequence 1:
Sequence 2: Allergen Der f 5.0101, Sequence: ABO84970
Sequence identity: 34.29 (48/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII----A----A-V-----G--K-------FD-L-M----------E
Sequence 2 MKFIIAI--AVCTLAVVC--VSGEPKKHDYQNEFDFLLMQRIHEQMRKGE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           --LLHL--Q----E----KE-KEQIL-E---------G---------KRT
Sequence 2 EALLHLQHQINTFEENPTKEMKEQILGEMDTIIALIDGVRGVLNRLMKRT

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL--FERYN-E-AL-S---L---L------VK--------
Sequence 2 DLDIFERYNVEIALKSNEILERDLKKEEQRVKKIEV----

Alignment 13
Sequence 1:
Sequence 2: Allergen Der p 5.0102, Sequence: P14004
Sequence identity: 32.86 (46/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII--F-A------VSG----DKK-D-----FD-L-ME-----I---E
Sequence 2 MKFIIAFFVATLAVMTVSGE---DKKHD-YQNEFDFLLMERIHEQIKKGE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           --L--L-EQ----E----KE-K--I--E---------G----------R-
Sequence 2 LALFYLQEQINHFEEKPTKEMKDKIVAEMDTIIAMIDGVRGVLDRLMQRK

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL--FE-YN-E-A--S---L---L------VK--------
Sequence 2 DLDIFEQYNLEMAKKSGDILERDLKKEEARVKKIEV----

Alignment 14
Sequence 1:
Sequence 2: Allergen Der p 5.0101, Sequence: CAA35692
Sequence identity: 32.86 (46/140)
Sequence 1 ----------------MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAF
           ----------------MKFII--F-A------VSG----DKK-D-----F
Sequence 2 LFLENKDPKPLKKISIMKFIIAFFVATLAVMTVSGE---DKKHD-YQNEF

Sequence 1 DRLMMEELETKIDQVEKGLLHLSEQYKELEKTKSKELKEQILRELTIGEN
           D-L-ME-----I---E--L--L-EQ----E----KE-K--I--E------
Sequence 2 DFLLMERIHEQIKKGELALFYLQEQINHFEEKPTKEMKDKIVAEMDTIIA

Sequence 1 FMKGALKFFEMEAKRTDLNMFERYNYEFALESIKLLIKKLDELAKKVKAV
           ---G----------R-DL--FE-YN-E-A--S---L---L------VK--
Sequence 2 MIDGVRGVLDRLMQRKDLDIFEQYNLEMAKKSGDILERDLKKEEARVKKI

Sequence 1 NPDEYY
           ------
Sequence 2 EV----

Alignment 15
Sequence 1:
Sequence 2: Allergen Der p 5.0102, Sequence: AAB32842
Sequence identity: 32.86 (46/140)
Sequence 1 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE
           MKFII--F-A------VSG----DKK-D-----FD-L-ME-----I---E
Sequence 2 MKFIIAFFVATLAVMTVSGE---DKKHD-YQNEFDFLLMERIHEQIKKGE

Sequence 1 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT
           --L--L-EQ----E----KE-K--I--E---------G----------R-
Sequence 2 LALFYLQEQINHFEAKPTKEMKDKIVAEMDTIIAMIDGVRGVLDRLMQRK

Sequence 1 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY
           DL--FE-YN-E-A--S---L---L------VK--------
Sequence 2 DLDIFEQYNLEMAKKSGDILERDLKKEEARVKKIEV----