The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology

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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Fus c 2

Sequence 19879659

Full FASTA alignment

Sequence name:
Query sequence:
MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTKHSVP
DVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGADP
RTLGAAAEKLGGLAQKRVAGA

NoAllergenSequence Link in
SwissProt/NCBI/PIR
View SequenceSequence
Length
bit scoreE score
1Fus c 2AAL79931Go!121184.07.7e-49
2Mala s 13.0101CAI78451Go!10571.64.5e-15
3Cop c 2Q9UW02Go!10669.91.5e-14
4Asp f 29.0101AJ937745Go!11063.71.1e-12
5Zea m 25.0101Q4W1F7Go!12862.33.7e-12
6Asp f 28.0101AJ937744Go!10860.41.1e-11
7Tri a 25.0101Q9LDX4Go!12556.91.4e-10
8Plo i 2.0101CBW45298Go!10656.61.5e-10
9Alt a 4CAA58999Go!43336.85.7e-04

Alignment made with FASTA 3.45
As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous.

Alignment 1
Sequence 1:
Sequence 2: Allergen Fus c 2, Sequence: AAL79931
Sequence identity: 100.00 (121/121)
Sequence 1 MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTKHSVP
           MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTKHSVP
Sequence 2 MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTKHSVP

Sequence 1 DVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGADP
           DVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGADP
Sequence 2 DVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGADP

Sequence 1 RTLGAAAEKLGGLAQKRVAGA
           RTLGAAAEKLGGLAQKRVAGA
Sequence 2 RTLGAAAEKLGGLAQKRVAGA



Alignment 2
Sequence 1:
Sequence 2: Allergen Mala s 13.0101, Sequence: CAI78451
Sequence identity: 37.19 (45/121)
Sequence 1 MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTKHSVP
           -V--I-S-D-----------VV-DF-A-WC-PCK-I-PV-E--S------
Sequence 2 -VQVISSYDQFKQVTGGDKVVVIDFWATWCGPCKMIGPVFEKISDTPA-G

Sequence 1 DVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGADP
           D---F-KV-VD-----AQ--GI-AMPTF-FFK-G------------GADP
Sequence 2 DKVGFYKVDVDEQSQIAQEVGIRAMPTFVFFKNGQKIDT-----VVGADP

Sequence 1 RTLGAAAEKLGGLAQKRVAGA
           --L-AA---------------
Sequence 2 SKLQAAITQHSA---------



Alignment 3
Sequence 1:
Sequence 2: Allergen Cop c 2, Sequence: Q9UW02
Sequence identity: 33.88 (41/121)
Sequence 1 MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTKHSVP
           MV--I---DE--KL--S------DF-A-WC-PC--I-P--E--S-K----
Sequence 2 MVQVISNLDEFNKLTNSGKIIIIDFWATWCGPCRVISPIFEKFSEKYGAN

Sequence 1 DVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGADP
           ----FAKV-VD---D------I-AMPTF---K-G---------V--GA-P
Sequence 2 NIV-FAKVDVDTASDISEEAKIRAMPTFQVYKDGQKI---DELV--GANP

Sequence 1 RTLGAAAEKLGGLAQKRVAGA
           --L-----K------------
Sequence 2 TALESLVQKSLA---------



Alignment 4
Sequence 1:
Sequence 2: Allergen Asp f 29.0101, Sequence: AJ937745
Sequence identity: 33.06 (40/121)
Sequence 1 ----MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTK
           ----------------K-------V-VD--A-WC-PCKAI-PV---LST-
Sequence 2 MSHNVEKITDAKVFKEKVQEGSGPVIVDCSATWCGPCKAISPVFQRLSTS

Sequence 1 HSVPDVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIK
           --------F----VD-----A---G--AMPTFMFFK-G--V------V--
Sequence 2 EEFKNA-KFYEIDVDELSEVAAELGVRAMPTFMFFKDGQKV----NEVV-

Sequence 1 GADPRTLGAAAEKLGGLAQKRVAGA
           GA-P--L-AA---------------
Sequence 2 GANPPALEAAIKAHVA---------



Alignment 5
Sequence 1:
Sequence 2: Allergen Zea m 25.0101, Sequence: Q4W1F7
Sequence identity: 33.06 (40/121)
Sequence 1 -----------------------MVHHITSNDELQKLLSSTTYVVVDFFA
           --------------------------------------S----VV-DF-A
Sequence 2 MAASEAAAAAATPVAPTEGTVIAIHSLEEWSIQIEEANSAKKLVVIDFTA

Sequence 1 DWCPPCKAIAPVYEQLSTKHSVPDVLAFAKVNVDHVQDAAQQYGITAMPT
           -WCPPC-A-AP-------K---P-V--F-KV-VD-----A-Q----AMPT
Sequence 2 TWCPPCRAMAPIFADMAKKS--PNVV-FLKVDVDEMKTIAEQFSVEAMPT

Sequence 1 FMFFKEGKQVAVNGQAVIKGADPRTLGAAAEKLGGLAQKRVAGA
           F-F--EG-----------K----R--GAA-E-L--------A--
Sequence 2 FLFMREGD---------VKD---RVVGAAKEELARKLELHMAS-



Alignment 6
Sequence 1:
Sequence 2: Allergen Asp f 28.0101, Sequence: AJ937744
Sequence identity: 29.75 (36/121)
Sequence 1 ---MVHHITSNDELQKLLSSTTYVVVDFFADWCPPCKAIAPVYEQLSTKH
           ----------N----K-L-S---VVVDFFA-WC-PC-A-AP----LS-K-
Sequence 2 MSHGKVIAVDNPIIYKALTSSGPVVVDFFATWCGPCRAVAPKVGELSEKY

Sequence 1 SVPDVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKG
           S------F--V-VD-V---A----I-AMPTF---K-G-------------
Sequence 2 SN---VRFIQVDVDKVRSVAHEMNIRAMPTFVLYKDGQPLEKRVVGGNVR

Sequence 1 ADPRTLGAAAEKLGGLAQKRVAGA
           ------------------------
Sequence 2 ELEEMIKSISA-------------



Alignment 7
Sequence 1:
Sequence 2: Allergen Tri a 25.0101, Sequence: Q9LDX4
Sequence identity: 27.27 (33/121)
Sequence 1 --------------------MVHHITSNDELQKLLSSTTYVVVDFFADWC
           ----------------------------------------VV-DF-A-WC
Sequence 2 MAASAATATAAAVGAGEVISVHSLEQWTMQIEEANAAKKLVVIDFTASWC

Sequence 1 PPCKAIAPVYEQLSTKHSVPDVLAFAKVNVDHVQDAAQQYGITAMPTFMF
           -PC---AP----L--K---P----F-KV-VD-----A-Q----AMPTF-F
Sequence 2 GPCRIMAPIFADLAKKF--PAAV-FLKVDVDELKSIAEQFSVEAMPTFLF

Sequence 1 FKEGKQVAVNGQAVIKGADPRTLGAAAEKLGGLAQKRVAGA
           -KEG--------A------------AA--------------
Sequence 2 MKEGDVKDRVVGAIKEELTNKVGLHAAQ-------------



Alignment 8
Sequence 1:
Sequence 2: Allergen Plo i 2.0101, Sequence: CBW45298
Sequence identity: 30.58 (37/121)
Sequence 1 MVHHITSNDELQKLLSST--TYVVVDFFADWCPPCKAIAPVYEQLSTKHS
           M--HI-----L---L-------VV-DF-A-WC-PCK-I-P----------
Sequence 2 MSIHIKDVEDLTARLTEAGDKLVVIDFMATWCGPCKIIGPKLDEIAAEMA

Sequence 1 VPDVLAFAKVNVDHVQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGA
           --D-----KV-VD---D-A--Y-I--MPTF-F-K-GK-V-----A-----
Sequence 2 --DSIVVVKVDVDECEDIATEYSINTMPTFVFVKNGKPVEQFSGANVEKL

Sequence 1 DPRTLGAAAEKLGGLAQKRVAGA
           ----L------------------
Sequence 2 RSTILKLK---------------



Alignment 9
Sequence 1:
Sequence 2: Allergen Alt a 4, Sequence: CAA58999
Sequence identity: 19.83 (24/121)
Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 MTKQALPAVSEVTKDTLEEFKTADKVVLVAYFAADDKASNETFTSVANGL

Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 RDNFLFGATNDAALAKAEGVKQPGLVCTSPSTTARTSSPRPSMRTYPRLR

Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 KVASTPLIGEVGPETYAGYMAAGIPLAYIFAETPEEREEFAKELKPLALK

Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 HKGEINFATIDAKSFGQHAGNLNLKVGTWPAFAIQRTEKNEKFPTNQEAK

Sequence 1 ---------------------------------MVHHITSNDELQKLLSS
           ----------------------------------V---------------
Sequence 2 ITEKEIGKFVDDFLAGKIDPSIKSEPIPESNDGPVTVVVAHNYKDVVIDN

Sequence 1 TTYVVVDFFADWCPPCKAIAPVYE---QLSTKHSVPDVLAFAKVN--VDH
           ---V-V-F-A-WC--CKA-AP-YE---QL------------AKV------
Sequence 2 DKDVLVEFYAPWCGHCKALAPKYEELGQLYASDELSKLVTIAKVDATLND

Sequence 1 VQDAAQQYGITAMPTFMFFKEGKQVAVNGQAVIKGADPRTLGAAAEKLGG
           V-D--Q-------P---F--------------------------------
Sequence 2 VPDEIQGF----LPSSLFPLARRMPQSTTLVPHCRGSRPVHRRERLTQAS

Sequence 1 LAQKRVAGA-----------------------------------------
           --------------------------------------------------
Sequence 2 ASVGEAVEDATESAKASASSATDSAASAVSEGTETVKSGASVASDSASSA

Sequence 1 -------------------------------------
           -------------------------------------
Sequence 2 ASEATKSVKSAASEVTNSASSAASEASASASSVKDEL


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