Department of Biochemistry and Molecular Biology

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SDAP - All Allergens

Go to: SDAP All allergens		Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc		Submit new allergen information to SDAP
Last Updated: Nov 1, 2021
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use. Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Hev b 7.02

Sequence 3087805

Full FASTA alignment

Sequence name:
Query sequence:
MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI
ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK
ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIPTFDIKL
LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT
FELIDGGAAATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT
GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL
FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTRLLEKQESR
INLDTGRLESIPGASTNEAAITKFAKLLSEERKLRQLK

No Allergen Sequence Link in
SwissProt/NCBI/PIR View Sequence Sequence
Length bit score E score
1 Hev b 7.02 CAA11041 Go! 388 627.8 2.5e-181
2 Hev b 7.02 CAA11042 Go! 388 616.7 5.7e-178
3 Hev b 7.01 AAC27724 Go! 388 615.9 9.6e-178
4 Sola t 1 AAA33819 Go! 386 188.8 3.6e-49
5 Sola t 1 CAA27588 Go! 386 185.5 3.4e-48
6 Sola t 1 CAA27571 Go! 386 185.3 4.0e-48
7 Sola t 1 CAA31575 Go! 386 184.8 5.7e-48
8 Sola t 1 P15476 Go! 377 183.3 1.6e-47

Alignment made with FASTA 3.45
As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous.

Alignment 1
Sequence 1:
Sequence 2: Allergen Hev b 7.02, Sequence: CAA11041
Sequence identity: 100.00 (388/388)
Sequence 1 MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI
           MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI
Sequence 2 MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI

Sequence 1 ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK
           ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK
Sequence 2 ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK

Sequence 1 ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIPTFDIKL
           ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIPTFDIKL
Sequence 2 ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIPTFDIKL

Sequence 1 LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT
           LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT
Sequence 2 LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT

Sequence 1 FELIDGGAAATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT
           FELIDGGAAATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT
Sequence 2 FELIDGGAAATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT

Sequence 1 GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL
           GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL
Sequence 2 GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL

Sequence 1 FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTRLLEKQESR
           FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTRLLEKQESR
Sequence 2 FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTRLLEKQESR

Sequence 1 INLDTGRLESIPGASTNEAAITKFAKLLSEERKLRQLK
           INLDTGRLESIPGASTNEAAITKFAKLLSEERKLRQLK
Sequence 2 INLDTGRLESIPGASTNEAAITKFAKLLSEERKLRQLK

Alignment 2
Sequence 1:
Sequence 2: Allergen Hev b 7.02, Sequence: CAA11042
Sequence identity: 97.94 (380/388)
Sequence 1 MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI
           MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI
Sequence 2 MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI

Sequence 1 ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK
           ADYFDIIAGTSTGGLITTMLTAPNEDKKP-YQAKDIKDFYLENCPKIFPK
Sequence 2 ADYFDIIAGTSTGGLITTMLTAPNEDKKPIYQAKDIKDFYLENCPKIFPK

Sequence 1 ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIPTFDIKL
           ESRD-YDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIP-FDIKL
Sequence 2 ESRDTYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIPAFDIKL

Sequence 1 LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT
           LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT
Sequence 2 LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT

Sequence 1 FELIDGGAAATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT
           FELIDGG-AA-NPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT
Sequence 2 FELIDGGVAAANPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT

Sequence 1 GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL
           GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL
Sequence 2 GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL

Sequence 1 FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTRLLEKQESR
           FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGT-LLEKQESR
Sequence 2 FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTELLEKQESR

Sequence 1 INLDTGRLESIPGASTNEAAITKFAKLLSEERKLRQLK
           INLDTGRLESIPGA-TNEAAI-KFAKLLSEERKLRQLK
Sequence 2 INLDTGRLESIPGAPTNEAAIAKFAKLLSEERKLRQLK

Alignment 3
Sequence 1:
Sequence 2: Allergen Hev b 7.01, Sequence: AAC27724
Sequence identity: 98.20 (381/388)
Sequence 1 MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI
           MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI
Sequence 2 MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILASLESKLQDLDGPDARI

Sequence 1 ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK
           ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK
Sequence 2 ADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLENCPKIFPK

Sequence 1 ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTLTDVIIPTFDIKL
           ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDT-TDVIIPTFDIKL
Sequence 2 ESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTVKDTSTDVIIPTFDIKL

Sequence 1 LLPVIFSSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT
           LLPVIF-SDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT
Sequence 2 LLPVIFPSDDAKCNALKNARLADVCISTSAAPVLLPAHSFTTEDDKNIHT

Sequence 1 FELIDGGAAATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT
           FELIDGG-AATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT
Sequence 2 FELIDGGVAATNPTLLALTHIRNEIIRQNPRFIGANLTESKSRLVLSLGT

Sequence 1 GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDFHLSAL
           GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVD-HLSAL
Sequence 2 GKSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNASSDMVDSHLSAL

Sequence 1 FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTRLLEKQESR
           FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGT-LLEKQESR
Sequence 2 FKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLVEIGTELLEKQESR

Sequence 1 INLDTGRLESIPGASTNEAAITKFAKLLSEERKLRQLK
           INLDTGRLESIPGA-TNEAAI-KFAKLLSEERKLRQLK
Sequence 2 INLDTGRLESIPGAPTNEAAIAKFAKLLSEERKLRQLK

Alignment 4
Sequence 1:
Sequence 2: Allergen Sola t 1, Sequence: AAA33819
Sequence identity: 43.56 (169/388)
Sequence 1 --------------MATGSTTLTQGKK-ITVLSIDGGGIRGIIPGIILAS
           ---------------AT-S-T--------TVLSIDGGGI-GIIP-IIL--
Sequence 2 MATTKSFLILFFMILATTSSTCAKLEEMVTVLSIDGGGIKGIIPAIILEF

Sequence 1 LESKLQDLDG-PDARIADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAK
           LE--LQ--D---DAR-ADYFD-I-GTSTGGL-T-M-T-PNE---P---AK
Sequence 2 LEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAK

Sequence 1 DIKDFYLENCPKIFPKESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTV
           DI--FY-E--P-IF------NY-----IGP-YDG-YL-------L----V
Sequence 2 DIVPFYFEHGPHIF------NYSG-SIIGPMYDGKYLLQVLQEKLGETRV

Sequence 1 KDTLTDVIIPTFDIKLLLPVIFS-SDDAKCNALKNARLADVCISTSAAPV
           ---LT-V-I--FDIK---PVIF--S--AK---L--A---D-C-ST-AAP-
Sequence 2 HQALTEVAISSFDIKTNKPVIFTKSNLAKSPEL-DAKMYDICYSTAAAPI

Sequence 1 LLPAHSFTTE-DDKNIHTFELIDGGAAAT-NPTLLALTHIRNEIIRQNPR
           --P-H-F-T------I--F-L-DGG-A----P-LL-L-----------P-
Sequence 2 YFPPHYFITHTSNGDIYEFNLVDGGVATVGDPALLSLS-VATRLAQEDPA

Sequence 1 FIGANLTESKSRLVLSLGTG-KSEYKEKYNADMTSKWRLYNWALYNGNSP
           F--------K--L-LSLGTG--SE----Y-A----KW----W-L------
Sequence 2 FSSIKSLDYKQMLLLSLGTGTNSEFDKTYTAQEAAKWGPLRWML------

Sequence 1 AVDIFSNA-SSDMVDFHLSALFKSLDCEDYYLRIQDDTLTGEESSGHIAT
           A-----NA-SS-M-D---S--F--------YLR-Q---LTG-------A-
Sequence 2 AIQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDAS

Sequence 1 EENLQRLVEIGTRLLEKQESRINLDTGRLESIPGASTNEAAITKFAKLLS
           E-N---LV--G--LL-K--S----D-------P---T-E-A---FAKLLS
Sequence 2 EANMELLVQVGETLLKKPVSK---DS------P--ETYEEALKRFAKLLS

Sequence 1 EERKLRQLK---
           ---KLR--K---
Sequence 2 DRKKLRANKASY

Alignment 5
Sequence 1:
Sequence 2: Allergen Sola t 1, Sequence: CAA27588
Sequence identity: 42.01 (163/388)
Sequence 1 ---------------MATGSTTLTQGKKITVLSIDGGGIRGIIPGIILAS
           -----------------T-ST--T-G---TVLSIDGGGI-GIIP-IIL--
Sequence 2 MATTKSFLILFFMILATTSSTCATLGEMVTVLSIDGGGIKGIIPAIILEF

Sequence 1 LESKLQDLDG-PDARIADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAK
           LE--LQ--D---DAR-ADYFD-I-GTSTGGL-T-M-T-PNE---P---AK
Sequence 2 LEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAK

Sequence 1 DIKDFYLENCPKIFPKESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTV
           DI--FY-E--P-IF------NY------GP-YDG-YL-------L----V
Sequence 2 DIVPFYFEHGPHIF------NYSG-SIFGPRYDGKYLLQVLQEKLGETRV

Sequence 1 KDTLTDVIIPTFDIKLLLPVIFSSDDAKCNALKNARLADVCISTSAAPVL
           ---LT-V-I--FDIK---PVIF------------A---D-C-ST-AAP--
Sequence 2 HQALTEVAISSFDIKTNKPVIFTKSNLAESPQLDAKMYDICYSTAAAPIY

Sequence 1 LPAHSFTTE-DDKNIHTFELIDGGAAAT-NPTLLALTHIRNEIIRQNPRF
           -P-H-F-T---------F-L-DG--A----P-LL-L-----------P-F
Sequence 2 FPPHHFVTHTSNGATYEFNLVDGAVATVGDPALLSLS-VATRLAQDDPAF

Sequence 1 IGANLTESKSRLVLSLGTG-KSEYKEKYNADMTSKWRLYNWALYNGNSPA
           --------K--L-LSLGTG--SE----Y-A----KW----W-L------A
Sequence 2 SSIKSLDYKQMLLLSLGTGTNSEFDKTYTAEEAAKWGPLRWML------A

Sequence 1 VDIFSNA-SSDMVDFHLSALFKSLDCEDYYLRIQDDTLTGEESSGHIATE
           -----NA-SS-M-D---S--F--------YLR-Q---LTG-------A-E
Sequence 2 IQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDASE

Sequence 1 ENLQRLVEIGTRLLEKQESRINLDTGRLESIPGASTNEAAITKFAKLLSE
           -N---LV--G--LL-K--S----D-------P---T-E-A---FAKLLS-
Sequence 2 ANMELLVQVGETLLKKPVSK---DS------P--ETYEEALKRFAKLLSD

Sequence 1 ERKLRQLK---
           --KLR--K---
Sequence 2 RKKLRANKASH

Alignment 6
Sequence 1:
Sequence 2: Allergen Sola t 1, Sequence: CAA27571
Sequence identity: 43.81 (170/388)
Sequence 1 --------------MATGSTTL-TQGKKITVLSIDGGGIRGIIPGIILAS
           ---------------AT-S-T--T-G---TVLSIDGGGI-GIIP--IL--
Sequence 2 MATTNSFTILIFMILATTSSTFATLGEMVTVLSIDGGGIKGIIPATILEF

Sequence 1 LESKLQDLDG-PDARIADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAK
           LE--LQ--D---DAR-ADYFD-I-GTSTGGL-T-M-T-PNE---P---AK
Sequence 2 LEGQLQEVDNNTDARLADYFDVIGGTSTGGLLTAMITTPNETNRPFAAAK

Sequence 1 DIKDFYLENCPKIFPKESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTV
           DI--FY-E--PKIF---S----------GP-YDG-YL-------L----V
Sequence 2 DIVPFYFEHGPKIF--QSSGSI-----FGPKYDGKYLMQVLQEKLGETRV

Sequence 1 KDTLTDVIIPTFDIKLLLPVIFS-SDDAKCNALKNARLADVCISTSAAPV
           ---LT-V-I--FDIK---PVIF--S--AK---L--A---D-C-ST-AAP-
Sequence 2 HQALTEVAISSFDIKTNKPVIFTKSNLAKSPEL-DAKMYDICYSTAAAPT

Sequence 1 LLPAHSFTTE-DDKNIHTFELIDGGAAATN-PTLLALTHIRNEIIRQNPR
           --P-H-F-T---------F-L-DG--A----P-LL-------------P-
Sequence 2 FFPPHYFATNTSNGDKYEFNLVDGAVATVDDPALLSIS-VATKLAQVDPK

Sequence 1 FIGANLTESKSRLVLSLGTGK-SEYKEKYNADMTSKWRLYNWALYNGNSP
           F--------K--L-LSLGTG--SE----Y-A--T-KW----W-L------
Sequence 2 FASIKSLNYKQMLLLSLGTGTTSEFDKTYTAEETAKWGTARWMLVIQK--

Sequence 1 AVDIFSNASSDMVDFHLSALFKSLDCEDYYLRIQDDTLTGEESSGHIATE
           -----S-ASS-M-D--LS--F--LD----YLR-Q---LTG-------A-E
Sequence 2 ---MTSAASSYMTDYYLSTAFQALDSQNNYLRVQENALTGTTTELDDASE

Sequence 1 ENLQRLVEIGTRLLEKQESRINLDTGRLESIPGASTNEAAITKFAKLLSE
           -N-Q-LV--G--LL-K--S--N---------P---T-E-A---FAKLLS-
Sequence 2 ANMQLLVQVGEDLLKKSVSKDN---------P--ETYEEALKRFAKLLSD

Sequence 1 ERKLRQLK---
           --KLR--K---
Sequence 2 RKKLRANKASY

Alignment 7
Sequence 1:
Sequence 2: Allergen Sola t 1, Sequence: CAA31575
Sequence identity: 42.53 (165/388)
Sequence 1 --------------MATGSTTLTQGKK-ITVLSIDGGGIRGIIPGIILAS
           ---------------AT-S-T--------TVLSIDGGGI-GIIP-IIL--
Sequence 2 MATTKSFLILFFMILATTSSTCAKLEEMVTVLSIDGGGIKGIIPAIILEF

Sequence 1 LESKLQDLDG-PDARIADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAK
           LE--LQ--D---DAR-ADYFD-I-GTSTGGL-T-M-T-PNE---P---AK
Sequence 2 LEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAK

Sequence 1 DIKDFYLENCPKIFPKESRDNYDPIHSIGPIYDGEYLRELCNNLLKDLTV
           DI--FY-E--P-IF------NY------GP-YDG-YL-------L----V
Sequence 2 DIVPFYFEHGPHIF------NYSG-SILGPMYDGKYLLQVLQEKLGETRV

Sequence 1 KDTLTDVIIPTFDIKLLLPVIFS-SDDAKCNALKNARLADVCISTSAAPV
           ---LT-V-I--FDIK---PVIF--S--AK---L--A---D-C-ST-AAP-
Sequence 2 HQALTEVAISSFDIKTNKPVIFTKSNLAKSPEL-DAKMYDICYSTAAAPI

Sequence 1 LLPAHSFTTEDDKNI-HTFELIDGGAAAT-NPTLLALTHIRNEIIRQNPR
           --P-H-F-T---------F-L-DG--A----P-LL-L-----------P-
Sequence 2 YFPPHHFVTHTSNGARYEFNLVDGAVATVGDPALLSLS-VATRLAQEDPA

Sequence 1 FIGANLTESKSRLVLSLGTG-KSEYKEKYNADMTSKWRLYNWALYNGNSP
           F--------K--L-LSLGTG--SE----Y-A----KW----W-L------
Sequence 2 FSSIKSLDYKQMLLLSLGTGTNSEFDKTYTAEEAAKWGPLRWML------

Sequence 1 AVDIFSNA-SSDMVDFHLSALFKSLDCEDYYLRIQDDTLTGEESSGHIAT
           A-----NA-SS-M-D---S--F--------YLR-Q---L-G-------A-
Sequence 2 AIQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALNGTTTEMDDAS

Sequence 1 EENLQRLVEIGTRLLEKQESRINLDTGRLESIPGASTNEAAITKFAKLLS
           E-N---LV--G--LL-K--S----D-------P---T-E-A---FAKLLS
Sequence 2 EANMELLVQVGETLLKKPVSK---DS------P--ETYEEALKRFAKLLS

Sequence 1 EERKLRQLK---
           ---KLR--K---
Sequence 2 DRKKLRANKASH

Alignment 8
Sequence 1:
Sequence 2: Allergen Sola t 1, Sequence: P15476
Sequence identity: 43.30 (168/388)
Sequence 1 -----MATGSTTLTQGKK-ITVLSIDGGGIRGIIPGIILASLESKLQDLD
           ------AT-S-T--------TVLSIDGGGI-GIIP-IIL--LE--LQ--D
Sequence 2 LFFMILATTSSTCAKLEEMVTVLSIDGGGIKGIIPAIILEFLEGQLQEVD

Sequence 1 G-PDARIADYFDIIAGTSTGGLITTMLTAPNEDKKPMYQAKDIKDFYLEN
           ---DAR-ADYFD-I-GTSTGGL-T-M-T-PNE---P---AKDI--FY-E-
Sequence 2 NNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAKDIVPFYFEH

Sequence 1 CPKIFPKESRDNYDPIHSI-GPIYDGEYLRELCNNLLKDLTVKDTLTDVI
           -P-IF------NY----SI-GP-YDG-YL-------L----V---LT-V-
Sequence 2 GPHIF------NYSG--SIFGPRYDGKYLLQVLQEKLGETRVHQALTEVA

Sequence 1 IPTFDIKLLLPVIFS-SDDAKCNALKNARLADVCISTSAAPVLLPAHSFT
           I--FDIK---PVIF--S--AK---L--A---D-C-S--AAP---P-H-F-
Sequence 2 ISSFDIKTNKPVIFTKSNLAKSPEL-DAKMYDICYSIAAAPIYFPPHHFV

Sequence 1 TE-DDKNIHTFELIDGGAAAT-NPTLLALTHIRNEIIRQNPRFIGANLTE
           T---------F-L-DGG-A----P-LL-L-----------P-F-------
Sequence 2 THTSNGATYEFNLVDGGVATVGDPALLSLS-VATRLAQEDPAFSSIKSLD

Sequence 1 SKSRLVLSLGTG-KSEYKEKYNADMTSKWRLYNWALYNGNSPAVDIFSNA
           -K--L-LSLGTG--SE----Y-A----KW----W-L------A-----NA
Sequence 2 YKQMLLLSLGTGTNSEFDKTYTAEEAAKWGPLRWML------AIQQLTNA

Sequence 1 -SSDMVDFHLSALFKSLDCEDYYLRIQDDTLTGEESSGHIATEENLQRLV
           -SS-M-D---S--F--------YLR-Q---LTG-------A-E-N---LV
Sequence 2 ASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDASEANMELLV

Sequence 1 EIGTRLLEKQESRINLDTGRLESIPGASTNEAAITKFAKLLSEERKLRQL
           --G--LL-K--S----D-------P---T-E-A---FAKLLS---KLR--
Sequence 2 QVGETLLKKPVSK---DS------P--ETYEEALKRFAKLLSNRKKLRAN

Sequence 1 K---
           K---
Sequence 2 KASY