Department of Biochemistry and Molecular Biology

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SDAP - All Allergens

Go to: SDAP All allergens		Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc		Submit new allergen information to SDAP
Last Updated: Nov 1, 2021
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use. Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Bra r 5.0101

Sequence P69197

Full FASTA alignment

Sequence name:
Query sequence:
MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAKIDT
DGDGNISFQEFTEFASANPGLMKDVAKVF

No Allergen Sequence Link in
SwissProt/NCBI/PIR View Sequence Sequence
Length bit score E score
1 Bra r 5.0101 P69197 Go! 79 87.3 5.3e-20
2 Bra n 2 Q39406 Go! 83 69.8 1.0e-14
3 Bra n 2 BAA09633 Go! 82 69.5 1.3e-14
4 Bet v 4 CAA73147 Go! 85 68.3 3.0e-14
5 Bet v 4 Q39419 Go! 85 67.5 5.1e-14
6 Aln g 4 O81701 Go! 85 67.2 6.3e-14
7 Ole e 3 O81092 Go! 84 66.1 1.3e-13
8 Che a 3 AAL92871 Go! 86 65.9 1.7e-13
9 Sal k 7.0101 ALE34025 Go! 86 65.9 1.7e-13
10 Syr v 3 P58171 Go! 81 64.4 4.2e-13
11 Par j 4.0101 CAP05019 Go! 84 64.4 4.3e-13
12 Phl p 7 O82040 Go! 78 63.5 7.9e-13
13 Cyn d 7 P94092 Go! 80 63.0 1.1e-12
14 Cyn d 7 CAA62634 Go! 82 63.0 1.1e-12
15 Art v 5.0101 AY904434 Go! 82 59.7 1.2e-11
16 Jun o 4 O64943 Go! 165 43.2 2.1e-06
17 Cup a 4.0101 ABP87672 Go! 177 43.2 2.2e-06
18 Amb a 10.0101 Q2KN25 Go! 160 42.8 2.6e-06
19 Ole e 8 AAF31152 Go! 171 41.0 9.7e-06
20 Ole e 8 Q9M7R0 Go! 171 39.2 3.5e-05
21 Der f 39.0101 QBF67841 Go! 153 34.0 1.1e-03
22 Der p 39.0101 QXY82447 Go! 153 34.0 1.1e-03
23 Bet v 3 P43187 Go! 205 33.4 2.4e-03
24 Per a 6.0101 Q1M0Y3 Go! 151 32.5 3.3e-03
25 Bla g 6.0301 ABB89298 Go! 154 31.7 5.6e-03

Alignment made with FASTA 3.45
As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous.

Alignment 1
Sequence 1:
Sequence 2: Allergen Bra r 5.0101, Sequence: P69197
Sequence identity: 100.00 (79/79)
Sequence 1 MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAKIDT
           MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAKIDT
Sequence 2 MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAKIDT

Sequence 1 DGDGNISFQEFTEFASANPGLMKDVAKVF
           DGDGNISFQEFTEFASANPGLMKDVAKVF
Sequence 2 DGDGNISFQEFTEFASANPGLMKDVAKVF

Alignment 2
Sequence 1:
Sequence 2: Allergen Bra n 2, Sequence: Q39406
Sequence identity: 78.48 (62/79)
Sequence 1 MADA----EHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMA
           MADA----EH-RIFKKFD--GDGKISA-EL--ALK-LGSVT-DD--RMMA
Sequence 2 MADATEKAEHDRIFKKFDANGDGKISASELGDALKNLGSVTHDDIKRMMA

Sequence 1 KIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           -IDTDGDG-IS-QEF--FASAN-GLMKDVAK-F
Sequence 2 EIDTDGDGYISYQEFSDFASANRGLMKDVAKIF

Alignment 3
Sequence 1:
Sequence 2: Allergen Bra n 2, Sequence: BAA09633
Sequence identity: 74.68 (59/79)
Sequence 1 ---MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAK
           ------AEH-RIFKKFD--GDGKISA-EL--ALK-LGSVT-DD--RMMA-
Sequence 2 ADATEKAEHDRIFKKFDANGDGKISASELGDALKNLGSVTHDDIKRMMAE

Sequence 1 IDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           IDTDGDG-IS-QEF--FASAN-GLMKDVAK-F
Sequence 2 IDTDGDGYISYQEFSDFASANRGLMKDVAKIF

Alignment 4
Sequence 1:
Sequence 2: Allergen Bet v 4, Sequence: CAA73147
Sequence identity: 74.68 (59/79)
Sequence 1 ------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRM
           ---------AE-ERIFK-FD--GDGKISAAEL-EALK-LGS-TPD-V--M
Sequence 2 MADDHPQDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHM

Sequence 1 MAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           MA-IDTDGDG-ISFQEFT-FA-AN-GL-KDVAK-F
Sequence 2 MAEIDTDGDGFISFQEFTDFARANRGLLKDVAKIF

Alignment 5
Sequence 1:
Sequence 2: Allergen Bet v 4, Sequence: Q39419
Sequence identity: 73.42 (58/79)
Sequence 1 ------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRM
           ---------AE-ERIFK-FD--GDGKISAAEL-EALK-LGS-TPD-V--M
Sequence 2 MADDHPQDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDEVKHM

Sequence 1 MAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           MA-IDTDGDG-ISFQEFT-F--AN-GL-KDVAK-F
Sequence 2 MAEIDTDGDGFISFQEFTDFGRANRGLLKDVAKIF

Alignment 6
Sequence 1:
Sequence 2: Allergen Aln g 4, Sequence: O81701
Sequence identity: 74.68 (59/79)
Sequence 1 ------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRM
           ---------AEHERIFK-FD--GDGKISA-EL--ALK-LGSVTPD-V--M
Sequence 2 MADDHPQDQAEHERIFKCFDANGDGKISASELGDALKTLGSVTPDEVKHM

Sequence 1 MAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           MA-IDTDGDG-ISFQEFT-FA-AN-GL-KDVAK-F
Sequence 2 MAEIDTDGDGFISFQEFTNFARANRGLVKDVAKIF

Alignment 7
Sequence 1:
Sequence 2: Allergen Ole e 3, Sequence: O81092
Sequence identity: 70.89 (56/79)
Sequence 1 -----MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMM
           --------AEHERIFK-FD--GDGKIS--EL-E-LK-LGSVTP----RMM
Sequence 2 MADDPQEVAEHERIFKRFDANGDGKISSSELGETLKTLGSVTPEEIQRMM

Sequence 1 AKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           A-IDTDGDG-ISF-EFT-FA-AN-GL-KDVAK-F
Sequence 2 AEIDTDGDGFISFEEFTVFARANRGLVKDVAKIF

Alignment 8
Sequence 1:
Sequence 2: Allergen Che a 3, Sequence: AAL92871
Sequence identity: 70.89 (56/79)
Sequence 1 -------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTR
           ----------A--ERIFK-FDT-GDGKIS--EL--ALK-LGSVTPD-V-R
Sequence 2 MAAEDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRR

Sequence 1 MMAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           MMA-IDTDGDG-ISF-EFT-FA-AN-GL-KDV-K-F
Sequence 2 MMAEIDTDGDGFISFDEFTDFARANRGLVKDVSKIF

Alignment 9
Sequence 1:
Sequence 2: Allergen Sal k 7.0101, Sequence: ALE34025
Sequence identity: 70.89 (56/79)
Sequence 1 -------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTR
           ----------A--ERIFK-FDT-GDGKIS--EL--ALK-LGSVT-D---R
Sequence 2 MAAEDTPQDLADRERIFKRFDTNGDGKISSSELGDALKTLGSVTSDEIVR

Sequence 1 MMAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           MMA-IDTDGDG-ISF-EFTEFA-AN-GL-KDVAK-F
Sequence 2 MMAEIDTDGDGFISFEEFTEFARANRGLIKDVAKIF

Alignment 10
Sequence 1:
Sequence 2: Allergen Syr v 3, Sequence: P58171
Sequence identity: 68.35 (54/79)
Sequence 1 --MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAKI
           -----AE-ERIFK-FD--GDGKIS--EL-E-LK-LGSVTP----RMMA-I
Sequence 2 MAEEVAELERIFKRFDANGDGKISSSELGETLKTLGSVTPEEIQRMMAEI

Sequence 1 DTDGDGNISFQEFTEFASANPGLMKDVAKVF
           DTDGDG-ISF-EF--FA-AN-GL-KDVAK-F
Sequence 2 DTDGDGFISFEEFKDFARANSGLIKDVAKIF

Alignment 11
Sequence 1:
Sequence 2: Allergen Par j 4.0101, Sequence: CAP05019
Sequence identity: 68.35 (54/79)
Sequence 1 -----MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMM
           --------AE-ERIFK-FD--GDGKIS--EL-EALK-LGSVT-D-V-RMM
Sequence 2 MADKQIDRAEQERIFKRFDSNGDGKISSSELGEALKALGSVTADEVHRMM

Sequence 1 AKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           A-IDTDGDG-IS--EF--FA-AN-GL-KD-AK-F
Sequence 2 AEIDTDGDGAISLEEFSSFADANRGLIKDIAKIF

Alignment 12
Sequence 1:
Sequence 2: Allergen Phl p 7, Sequence: O82040
Sequence identity: 69.62 (55/79)
Sequence 1 MADAEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAKIDT
           MAD---ERIFK-FDT-GDGKIS--EL--AL--LGS---D-V-RMMA-IDT
Sequence 2 MAD-DMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDT

Sequence 1 DGDGNISFQEFTEFASANPGLMKDVAKVF
           DGDG-I-F-EF--F--ANPGLMKDVAKVF
Sequence 2 DGDGFIDFNEFISFCNANPGLMKDVAKVF

Alignment 13
Sequence 1:
Sequence 2: Allergen Cyn d 7, Sequence: P94092
Sequence identity: 69.62 (55/79)
Sequence 1 MADA-EHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAKID
           MAD----E-IFK-FDT-GDGKIS-AEL--AL--LGS---D-V-RMMA-ID
Sequence 2 MADTGDMEHIFKRFDTNGDGKISLAELTDALRTLGSTSADEVQRMMAEID

Sequence 1 TDGDGNISFQEFTEFASANPGLMKDVAKVF
           TDGDG-I-F-EF--F--ANPGLMKDVAKVF
Sequence 2 TDGDGFIDFDEFISFCNANPGLMKDVAKVF

Alignment 14
Sequence 1:
Sequence 2: Allergen Cyn d 7, Sequence: CAA62634
Sequence identity: 69.62 (55/79)
Sequence 1 --MADA-EHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAK
           --MAD----E-IFK-FDT-GDGKIS-AEL--AL--LGS---D-V-RMMA-
Sequence 2 KTMADTGDMEHIFKRFDTNGDGKISLAELTDALRTLGSTSADEVQRMMAE

Sequence 1 IDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           IDTDGDG-I-F-EF--F--ANPGLMKDVAKVF
Sequence 2 IDTDGDGFIDFDEFISFCNANPGLMKDVAKVF

Alignment 15
Sequence 1:
Sequence 2: Allergen Art v 5.0101, Sequence: AY904434
Sequence identity: 67.09 (53/79)
Sequence 1 MAD---AEHERIFKKFDTDGDGKISAAELEEALKKLGSVTPDDVTRMMAK
           MAD---AE--RIF--FD--GDGKISAAEL-E-L-KLGSV-P--V--MM--
Sequence 2 MADEDKAECDRIFGAFDKNGDGKISAAELGESLTKLGSVSPEEVQTMMDE

Sequence 1 IDTDGDGNISFQEFTEFASANPGLMKDVAKVF
           -DTDGDG-IS--EF-EF--AN-GLMKDV-K-F
Sequence 2 LDTDGDGYISYDEFAEFFNANRGLMKDVGKIF

Alignment 16
Sequence 1:
Sequence 2: Allergen Jun o 4, Sequence: O64943
Sequence identity: 45.57 (36/79)
Sequence 1 ---------------------MADAEHERIFKKFDTDGDGKISAAELEEA
           -------------------------E-E--FKKFD--GDGKIS--EL---
Sequence 2 MDEVPSSDGSKSACSGEVVMEQSVHELEEVFKKFDANGDGKISGSELADI

Sequence 1 LKKLGS-VTPDDVTRMMAKIDTDGDGNISFQEFTEFASANPGL--MKDVA
           L--LGS-V----V--MM---D-DGDG--S-QEF-------------K---
Sequence 2 LRSLGSDVGEAEVKAMMEEADADGDGYVSLQEFVDLNNKGASVKDLKNAF

Sequence 1 KVF-----------------------------------------------
           KVF-----------------------------------------------
Sequence 2 KVFDRDCNGSISAAELCHTLESVGEPCTIEESKNIIHNVDKNGDGLISVE

Sequence 1 ---------------
           ---------------
Sequence 2 EFQTMMTSEMTDKSK

Alignment 17
Sequence 1:
Sequence 2: Allergen Cup a 4.0101, Sequence: ABP87672
Sequence identity: 44.30 (35/79)
Sequence 1 ---------------------------------MADAEHERIFKKFDTDG
           -------------------------------------E-E--FKKFD--G
Sequence 2 MRGSHHHHHHGSMDEVPSSDGSKSASSGKRVLEQSVHELEEVFKKFDANG

Sequence 1 DGKISAAELEEALKKLGS-VTPDDVTRMMAKIDTDGDGNISFQEFTEFAS
           DGKIS--EL---L---GS-V----V--MM---DTDGDG--S-QEF-----
Sequence 2 DGKISGSELADILRSMGSEVDEAEVKAMMEEADTDGDGYVSLQEFVDL-N

Sequence 1 ANPGLMKDVAKVF-------------------------------------
           ------KD----F-------------------------------------
Sequence 2 IKGATVKDLKNAFKVFDRDCNGTISPAELCQTLKSMGEPCTIEESKNIIH

Sequence 1 ----------------------------
           ----------------------------
Sequence 2 NVDKNGDGLISVEEFQTMMTSEMTDKSK

Alignment 18
Sequence 1:
Sequence 2: Allergen Amb a 10.0101, Sequence: Q2KN25
Sequence identity: 44.30 (35/79)
Sequence 1 ------------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGS-VT
           ----------------E---IF--FDT-GDG-IS--EL---LK-LGS---
Sequence 2 MAPENNKHSIFPTDKEEVTKIFNRFDTNGDGQISEDELFAILKSLGSDTS

Sequence 1 PDDVTRMMAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF--------
           PD-V-R-MA-ID-DGDG-IS--EF--F-----------------------
Sequence 2 PDEVKRVMAEIDADGDGFISLDEFILFCKGIESEGDEINDLKEAFKFYDQ

Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 NNNGVISANELHQILGRLGENYSVESCADMIKSVDSDGDGFVDFEEFRKM

Sequence 1 ----------
           ----------
Sequence 2 MSRKGGDGAM

Alignment 19
Sequence 1:
Sequence 2: Allergen Ole e 8, Sequence: AAF31152
Sequence identity: 41.77 (33/79)
Sequence 1 ---------------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGS
           -------------------E----F--FD--GDGKIS--EL--ALK-LGS
Sequence 2 MAANTDRNSKPSVYLQEPNEVQGVFNRFDANGDGKISGDELACALKALGS

Sequence 1 -VTPDDVTRMMAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF-----
           --------RMM--IDTD-DG-I--QEF--F--A-----------------
Sequence 2 NTSKEEIARMMEEIDTDKDGFINVQEFAAFVKAETDPYPSSGGENELKEA

Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 FELYDQDHNGLISSVELHKILTRLGERYAEHDCVEMIKSVDSDGDGYVSF

Sequence 1 ---------------------
           ---------------------
Sequence 2 EEFKKMMTNKSGNNSQAEPPK

Alignment 20
Sequence 1:
Sequence 2: Allergen Ole e 8, Sequence: Q9M7R0
Sequence identity: 39.24 (31/79)
Sequence 1 ---------------MADAEHERIFKKFDTDGDGKISAAELEEALKKLGS
           -------------------E----F--FD--GDGKIS--EL---LK-LGS
Sequence 2 MAANTDRNSKPSVYLQEPNEVQGVFNRFDANGDGKISGDELAGVLKALGS

Sequence 1 -VTPDDVTRMMAKIDTDGDGNISFQEFTEFASANPGLMKDVAKVF-----
           --------R-M--IDTD-DG-I--QEF--F--A-----------------
Sequence 2 NTSKEEIGRIMEEIDTDKDGFINVQEFAAFVKAETDPYPSSGGENELKEA

Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 FELYDQDHNGLISSVELHKILTRLGERYAEHDCVEMIKSVDSDGDGYVSF

Sequence 1 ---------------------
           ---------------------
Sequence 2 EEFKKMMTNKSGNNSQAEPPK

Alignment 21
Sequence 1:
Sequence 2: Allergen Der f 39.0101, Sequence: QBF67841
Sequence identity: 32.91 (26/79)
Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 MSVEELTKEQVQMLRKAFDMFDREKKGHIHTNMVSTILRTLGQTFEEKDL

Sequence 1 -------------------------------MADAEHERI---FKKFDTD
           --------------------------------A-A--E-----F---D--
Sequence 2 QQLITEIDADGSGELEFDEFLTLTARFLVEEDAEAMQEELREAFRMYDKE

Sequence 1 GDGKISAAELEEALKKLGS-VTPDDVTRMMAKIDTDGDGNISFQEFTEFA
           G-G-I----L-E-L--L----T-D----M-A-IDTDG-G---F-EF-E--
Sequence 2 GNGYIPTSALREILRALDDKLTNDELDEMIAEIDTDGSGTVDFDEFMEMM

Sequence 1 SANPGLMKDVAKVF
           --------------
Sequence 2 TGD-----------

Alignment 22
Sequence 1:
Sequence 2: Allergen Der p 39.0101, Sequence: QXY82447
Sequence identity: 32.91 (26/79)
Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 MSVEELTKEQVQMLRKAFDMFDREKKGHIHTNMVSTILRTLGQTFEEKDL

Sequence 1 -------------------------------MADAEHERI---FKKFDTD
           --------------------------------A-A--E-----F---D--
Sequence 2 QTLITEIDADGSGELEFDEFLTLTARFLVEEDAEAMQEELREAFRMYDKE

Sequence 1 GDGKISAAELEEALKKLGS-VTPDDVTRMMAKIDTDGDGNISFQEFTEFA
           G-G-I----L-E-L--L----T-D----M-A-IDTDG-G---F-EF-E--
Sequence 2 GNGYIPTSALREILRALDDKLTNDELDEMIAEIDTDGSGTVDFDEFMEMM

Sequence 1 SANPGLMKDVAKVF
           --------------
Sequence 2 TGD-----------

Alignment 23
Sequence 1:
Sequence 2: Allergen Bet v 3, Sequence: P43187
Sequence identity: 34.18 (27/79)
Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 MPCSTEAMEKAGHGHASTPRKRSLSNSSFRLRSESLNTLRLRRIFDLFDK

Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 NSDGIITVDELSRALNLLGLETDLSELESTVKSFTREGNIGLQFEDFISL

Sequence 1 -----------------------------MADAEHERIFKKFDTDGDGKI
           --------------------------------A-----FK-FD-DGDG-I
Sequence 2 HQSLNDSYFAYGGEDEDDNEEDMRKSILSQEEADSFGGFKVFDEDGDGYI

Sequence 1 SAAELEEALKKLG---SVTPDDVTRMMAKIDTDGDGNISFQEFTEFASAN
           SA-EL---L-KLG-------D-V--M----D---DG---F-EF-------
Sequence 2 SARELQMVLGKLGFSEGSEIDRVEKMIVSVDSNRDGRVDFFEFKDMMRSV

Sequence 1 PGLMKDVAKVF
           -----------
Sequence 2 LVRSS------

Alignment 24
Sequence 1:
Sequence 2: Allergen Per a 6.0101, Sequence: Q1M0Y3
Sequence identity: 29.11 (23/79)
Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 MDELPDEQIQLLKKAFDAFDREKNGFISTDMVGTILEMLGHPLDDDMLEE

Sequence 1 --------------------------------MADAEHERIFKKFDTDGD
           ------------------------------------E----F---D--G-
Sequence 2 IIAEVDADGSGELEFQEFVTLAARFLVEEDAEAMQQELKEAFRLYDKEGN

Sequence 1 GKISAAELEEALKKLGS-VTPDDVTRMMAKIDTDGDGNISFQEFTEFASA
           G-I----L-E-LK-L----T--D---M---ID-DG-G---F-EF-E----
Sequence 2 GYITTTVLREILKELDDKLTNEDLDAMIEEIDSDGSGTVDFDEFMEVMTG

Sequence 1 NPGLMKDVAKVF
           ------------
Sequence 2 E-----------

Alignment 25
Sequence 1:
Sequence 2: Allergen Bla g 6.0301, Sequence: ABB89298
Sequence identity: 27.85 (22/79)
Sequence 1 --------------------------------------------------
           --------------------------------------------------
Sequence 2 MADEQLQLPPEQISVLRKAFDAFDREKSGSISTNMVEEILRLMGQPFNRR

Sequence 1 ------------------------------------MADAEHERIFKKFD
           ----------------------------------------E----F---D
Sequence 2 TLEELIDEVDADKSGRLEFDEFVTLAAKFIIEEDSEAMEKELREAFRLYD

Sequence 1 TDGDGKISAAELEEALKKLG-SVTPDDVTRMMAKIDTDGDGNISFQEFTE
           --G-G-I----L-E-L--L----T-D----M---ID-DG-G---F-EF-E
Sequence 2 KEGNGYIPTSCLREILRELDEQLTSDELDMMIEEIDADGSGTVDFDEFME

Sequence 1 FASANPGLMKDVAKVF
           ----------------
Sequence 2 MMTG------------