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SDAP - All Allergens
Allergen group: Ara h 2 | Allergen Ara h 2.0101Translate to AllerML |  |  | | Allergen | Ara h 2.0101 | | Type | foods | | Species - Systematic Name | Arachis hypogaea | | Species - Common Name | peanut | | Keywords | Conglutin | | Class | IUIS |
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| Ara h 2.0101 - PubMed | Reference | | Reference 1 | Kleber-Janke T, Crameri R, Appenzeller U, Schlaak M, Becker WM. Selective cloning of peanut allergens, including profilin and 2S albumins, by phage display technology. Int Arch Allergy Immunol. 1999 Aug;119(4):265-74. doi: 10.1159/000024203. PMID: 10474031 | | Reference 2 | Chatel JM, Bernard H, Orson FM. Isolation and characterization of two complete Ara h 2 isoforms cDNA. Int Arch Allergy Immunol. 2003 May;131(1):14-8. doi: 10.1159/000070429. PMID: 12759484 | | Reference 3 | Stanley JS, King N, Burks AW, Huang SK, Sampson H, Cockrell G, Helm RM, West CM, Bannon GA. Identification and mutational analysis of the immunodominant IgE binding epitopes of the major peanut allergen Ara h 2. Arch Biochem Biophys. 1997 Jun 15;342(2):244-53. doi: 10.1006/abbi.1997.9998. PMID: 9186485 |
Ara h 2.0101 - Protein Sequences
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources
Ara h 2.0101 - Protein Sequence Properties
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
Ara h 2.0101 - Protein Models
These 3D allergen models are superseded by newer PDB structures.
Ara h 2.0101 - Pfam domains
| Sequence | Pfam sequence | Pfam family | Allergens from
this Pfam family | Pfam database | Pfam region | First amino acid | Last amino acid | | ACN62248 | | | | | | | | | | Q941R0_ARAHY | PF00234 | Go! | Pfam A | 1 | 42 | 145 | | | | PF00234: Protease inhibitor/seed storage/LTP family
| | 15418705 | | | | | | | | | | Q941R0_ARAHY | PF00234 | Go! | Pfam A | 1 | 45 | 148 | | | | PF00234: Protease inhibitor/seed storage/LTP family
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Pfam is a database of multiple sequence alignments and hidden Markov models covering protein domains and families
Inspect MotifMate results for Ara h 2.0101. AutoMotif contains a database of PCPMer motifs for allergens.
MotifMate home page
MotifMate summary
Browse MotifMate proteins
Browse MotifMate families
Ara h 2.0101 - Sequences from the Entrez Nucleotides database
| Link to GenBank | View Sequence | | 1236995 | Go! |
Ara h 2.0101 - PDB Structures
| PDB Accession | Jmol | Deposition date | Experimental | Observation | | 3OB4 | View! | 2010-08-06 | X-ray diffraction resolution 2.71 A | maltose-binding protein (MBP)-Ara h 2 fusion system | | 8DB4 | View! | 2023-01-25 | X-ray diffraction resolution 2.3 A | Crystal structure of the peanut allergen Ara h 2 bound by two neutralizing antibodies 22S1 and 13T1 |
Ara h 2.0101 - EpitopesJ. S. Stanley, N. King, A. W. Burks, S. K. Huang, H. Sampson, G. Cockrell,
R. M. Helm, C. M. West, and G. A. Bannon,
Identification and mutational analysis of the immunodominant IgE binding
epitopes of the major peanut allergen Ara h 2,
Arch. Biochem. Biophys. 1997, 342, 244-253.
Ara h 2.0101 - Epitopes| No | Epitope | Exact
Match
@SDAP | Peptide
Similarity
@SDAP | Exact
Match
@PIR | Position | Type | Description | | 1 | RQQWELQGDRRCQSQLERAN | Go! | Go! | Go! | 22-41 | T-cell | recognized by 3 subjects out of 8
| | 2 | RRCQSQLERANLRPCEQHLM | Go! | Go! | Go! | 31-51 | T-cell | recognized by 2 subjects out of 8
| | 3 | PYDRRGAGSSQHQERCCNEL | Go! | Go! | Go! | 76-95 | T-cell | recognized by 3 subjects out of 8
| | 4 | RCMCEALQQIMENQSDRLQG | Go! | Go! | Go! | 103-122 | T-cell | recognized by 2 subjects out of 8
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I. N. Glaspole, M. P. de Leon, J. M. Rolland, and R. E. O'Hehir,
Characterization of the T-cell epitopes of a major peanut allergen, Ara h 2,
Allergy 2005, 60, 35-40.
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