Department of Biochemistry and Molecular Biology

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SDAP - All Allergens

Go to: SDAP All allergens		Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc		Submit new allergen information to SDAP
Last Updated: Nov 1, 2021
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use. Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Fel d 7.0101

Sequence 301072397

Full FASTA alignment

Sequence name:
Query sequence:
MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRETSWKK
PELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTTYGG
KRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALENFRE
FLRAKGFNQEIFSPKQSDTCPPGTDQEPEV

No Allergen Sequence Link in
SwissProt/NCBI/PIR View Sequence Sequence
Length bit score E score
1 Fel d 7.0101 ADK56160 Go! 180 290.4 2.0e-80
2 Can f 1 O18873 Go! 174 190.2 2.9e-50
3 Equ c 1 Q95182 Go! 187 57.5 2.6e-10
4 Can f 2 O18874 Go! 180 56.1 6.9e-10
5 Can f 6.0101 XP_855342 Go! 190 54.2 2.7e-09
6 Bos d 5 P02754 Go! 178 52.3 9.7e-09
7 Cav p 6.0101 S0BDX9 Go! 181 52.0 1.2e-08
8 Bos d 5 CAA32835 Go! 178 49.2 8.3e-08
9 Rat n 1 P02761 Go! 181 48.2 1.6e-07
10 Fel d 4 AAS77253 Go! 186 47.5 2.7e-07
11 Mus m 1 P02762 Go! 180 46.5 5.2e-07
12 Mus m 1.0102 AAA39768 Go! 180 45.8 8.5e-07
13 Bos d 5 AAA30411 Go! 151 43.3 4.0e-06
14 Ory c 4.0101 U6C8D6 Go! 172 42.4 8.4e-06
15 Phod s 1.0101 S5ZYD3 Go! 151 35.0 1.3e-03
16 Cav p 3.0101 CAX62130 Go! 170 34.1 2.7e-03

Alignment made with FASTA 3.45
As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous.

Alignment 1
Sequence 1:
Sequence 2: Allergen Fel d 7.0101, Sequence: ADK56160
Sequence identity: 100.00 (180/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRETSWKK
           MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRETSWKK
Sequence 2 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRETSWKK

Sequence 1 PELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTTYGG
           PELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTTYGG
Sequence 2 PELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTTYGG

Sequence 1 KRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALENFRE
           KRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALENFRE
Sequence 2 KRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALENFRE

Sequence 1 FLRAKGFNQEIFSPKQSDTCPPGTDQEPEV
           FLRAKGFNQEIFSPKQSDTCPPGTDQEPEV
Sequence 2 FLRAKGFNQEIFSPKQSDTCPPGTDQEPEV

Alignment 2
Sequence 1:
Sequence 2: Allergen Can f 1, Sequence: O18873
Sequence identity: 61.11 (110/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRETSWKK
           MK-LLL--G-SLI--LQAQD-PA-G-DT-A-SGKWYLKAM--D-E----K
Sequence 2 MKTLLLTIGFSLIAILQAQDTPALGKDTVAVSGKWYLKAMTADQEVP-EK

Sequence 1 PELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTTYGG
           P--VTPM-L----GGNL-A--T-LTNGQC------L-KTSEP-KYT-Y-G
Sequence 2 PDSVTPMILKAQKGGNLEAKITMLTNGQCQNITVVLHKTSEPGKYTAYEG

Sequence 1 KRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALENFRE
           -RVV-I-P--V-DHYI-YCEGE--G-Q-RMAKL-GRDPE---EALE-FRE
Sequence 2 QRVVFIQPSPVRDHYILYCEGELHGRQIRMAKLLGRDPEQSQEALEDFRE

Sequence 1 FLRAKGFNQEIFSPKQSDTCPPGTDQEPEV
           F-RAKG-NQEI----QS-TC-PG-------
Sequence 2 FSRAKGLNQEILELAQSETCSPGGQ-----

Alignment 3
Sequence 1:
Sequence 2: Allergen Equ c 1, Sequence: Q95182
Sequence identity: 26.67 (48/180)
Sequence 1 MKALLLAVGLSLITVLQAQ--DPPASGEDTMAMSGKWYLKAMITD-RETS
           MK-LLL--GL-L----Q----D------D----SG-WY------D--E--
Sequence 2 MKLLLLCLGLILVCAQQEENSDVAIRNFDISKISGEWYSIFLASDVKEKI

Sequence 1 WKKPEL-VTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYT
           -------V-------L----L-AE-----NG-C-E------KT-E---Y-
Sequence 2 EENGSMRVFVDVIRALDNSSLYAEYQTKVNGECTEFPMVFDKTEEDGVYS

Sequence 1 -TYGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEAL
           --Y-G--V--I---E---H-I-Y-----------------R-P----E--
Sequence 2 LNYDGYNVFRISEFENDEHIILYLVNFDKDRPFQLFEFYAREPDVSPEIK

Sequence 1 ENFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV-
           E-F-------G---E-I------D-C-----------
Sequence 2 EEFVKIVQKRGIVKENIIDLTKIDRCFQLRGNGVAQA

Alignment 4
Sequence 1:
Sequence 2: Allergen Can f 2, Sequence: O18874
Sequence identity: 27.78 (50/180)
Sequence 1 MKALLLAVGLSLITVLQAQD----PPASGEDTMAMSGKWYLKAMITDRET
           M--LLL-VGL-LI--LQAQ------P--G------SG-W---A-------
Sequence 2 MQLLLLTVGLALICGLQAQEGNHEEPQGGLEEL--SGRWHSVALASNK-S

Sequence 1 SWKKPE---LVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPK
           ---KP-----V----------GNL---------GQC--V-L---KT----
Sequence 2 DLIKPWGHFRVFIHSMSA-KDGNLHGDILIPQDGQCEKVSLTAFKTATSN

Sequence 1 KYTT-YGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNE
           K----Y-G----Y------K---I-Y------------A-L--RD-----
Sequence 2 KFDLEYWGHNDLYLAEVDPKSYLILYMINQYNDDTSLVAHLMVRDLSRQQ

Sequence 1 EALENFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV
           --L--F-------G-----I------D-C----D-----
Sequence 2 DFLPAFESVCEDIGLHKDQIVVLSDDDRCQGSRD-----

Alignment 5
Sequence 1:
Sequence 2: Allergen Can f 6.0101, Sequence: XP_855342
Sequence identity: 26.11 (47/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGE-DTMAMSGKWYLKAMITD-RETSW
           MK-LLL--GL-L------------G--D----SG-WY------D--E---
Sequence 2 MKLLLLCLGLILVHAHEEENDVVKGNFDISKISGDWYSILLASDIKEKIE

Sequence 1 KKPEL-VTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKY-T
           ------V------VL----L--------NG-C----LI--KT-----Y--
Sequence 2 ENGSMRVFVKDIEVLSNSSLIFTMHTKVNGKCTKISLICNKTEKDGEYDV

Sequence 1 TYGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALE
           ---G-----I--T---D--IF------Q--------L-GR-P-------E
Sequence 2 VHDGYNLFRIIETAYEDYIIFHLNNVNQEQEFQLMELYGRKPDVSPKVKE

Sequence 1 NFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV-----
           -F-----------E-I----Q-D-C------E--------
Sequence 2 KFVRYCQGMEIPKENILDLTQVDRCLQARQSEAAQVSSAE

Alignment 6
Sequence 1:
Sequence 2: Allergen Bos d 5, Sequence: P02754
Sequence identity: 27.22 (49/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRET---S
           MK-LLLA--L--------------G-D-----G-WY--AM----------
Sequence 2 MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDA

Sequence 1 WKKPELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPK--KY
           ---P--V----L-----G-L--------NG-C-----I-EKT--P---K-
Sequence 2 QSAPLRVYVEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKI

Sequence 1 TTYGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEAL
           -------V-----T--K----F--E-----EQ--------R-PE---EAL
Sequence 2 DALNENKVLVLD-TDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDDEAL

Sequence 1 ENFREFLRAKGFNQEI-FSPKQ-SDTCPPGTDQEPEV
           E-F---L-A--------F-P-Q----C----------
Sequence 2 EKFDKALKALPMHIRLSFNPTQLEEQCHI--------

Alignment 7
Sequence 1:
Sequence 2: Allergen Cav p 6.0101, Sequence: S0BDX9
Sequence identity: 25.00 (45/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGE-DTMAMSGKWYLKAMITD-RETSW
           MK--LL--GL-L-------D----G--D----SG-WY------D-RET--
Sequence 2 MKLQLLCLGLILLCTQGEGDEVVRGNFDAEKISGNWYTVKEASDKRETIE

Sequence 1 KKPEL-VTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTT
           ------V------------L--------NG-CK---LI-----E------
Sequence 2 EGGSMRVFVESIEPVKDSALSFKFWAHENGECKQISLICNRVAEGVYAVE

Sequence 1 YGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALEN
           Y-G--V-----T--K---IF---------------L-GR-P----E----
Sequence 2 YDGYNVFRVAETDYKNYAIFQLRNFKAEGSFQLLELYGREPDVSGEIKTR

Sequence 1 FREFLRAKGFNQ-EIFSPKQSDTCPPGTDQEPEV
           F--F----G-----I------D-C----------
Sequence 2 FEDFCHKNGIGEGNIIDMTTVDRCLQARGEK---

Alignment 8
Sequence 1:
Sequence 2: Allergen Bos d 5, Sequence: CAA32835
Sequence identity: 27.22 (49/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRET---S
           MK-LLLA--L--------------G-D-----G-WY--AM----------
Sequence 2 MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDA

Sequence 1 WKKPELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPK--KY
           ---P--V----L-----G-L--------N--C-----I-EKT--P---K-
Sequence 2 QSAPLRVYVEELKPTPEGDLEILLQKWENDECAQKKIIAEKTKIPAVFKI

Sequence 1 TTYGGKRVVYIEPTEVKDHYIFYC-EGEMQGEQARMAKLVGRDPESNEEA
           -------V-----T--K--Y---C-E-----EQ--------R-PE---EA
Sequence 2 DALNENKVLVLD-TDYK-KYLLVCMENSAEPEQSLVCQCLVRTPEVDDEA

Sequence 1 LENFREFLRAKGFNQEI-FSPKQ-SDTCPPGTDQEPEV
           LE-F---L-A--------F-P-Q----C----------
Sequence 2 LEKFDKALKALPMHIRLSFNPTQLEEQCHI--------

Alignment 9
Sequence 1:
Sequence 2: Allergen Rat n 1, Sequence: P02761
Sequence identity: 23.89 (43/180)
Sequence 1 --MKALLLAVGLSLITVLQAQDPPASGE-DTMAMSGKWYLKAMITD-RET
           -----LLL--GL-L------------G--D-----G-W---------RE-
Sequence 2 MKLLLLLLCLGLTLVCGHAEEASSTRGNLDVAKLNGDWFSIVVASNKREK

Sequence 1 SWKKPELVTPMT-LTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKY
           ----------M----VLE---L--------NG-C-E--L---KT-E---Y
Sequence 2 IEENGSMRVFMQHIDVLEN-SLGFKFRIKENGECRELYLVAYKTPEDGEY

Sequence 1 -TTYGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEA
           ---Y-G-----I--T-------F-------GE------L-GR--------
Sequence 2 FVEYDGGNTFTILKTDYDRYVMFHLINFKNGETFQLMVLYGRTKDLSSDI

Sequence 1 LENFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV
           -E-F-----A-G-----I------D-C----------
Sequence 2 KEKFAKLCEAHGITRDNIIDLTKTDRCLQARG-----

Alignment 10
Sequence 1:
Sequence 2: Allergen Fel d 4, Sequence: AAS77253
Sequence identity: 26.11 (47/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITD-RETSWK
           MK-LLL--GL-L-----------S--D----SG-WY------D--E----
Sequence 2 MKLLLLCLGLILVCAHEEENVVRSNIDISKISGEWYSILLASDVKEKIEE

Sequence 1 KPEL-VTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTTY
           -----V-------L----L--------NG-C-E--L---KT--------Y
Sequence 2 NGSMRVFVEHIKALDNSSLSFVFHTKENGKCTEIFLVADKTKDGVYTVVY

Sequence 1 GGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLV---GRDPESNEEAL
           -G--V--I--T-V-D-YI------------R---LV----R-P-------
Sequence 2 DGYNVFSIVET-VYDEYILL--HLLNFDKTRPFQLVEFYAREPDVSQKLK

Sequence 1 ENFREFLRAKGFNQEIFSPKQSDTCPPGTDQEPEV-----
           E-F-------G----I------D-C------E--------
Sequence 2 EKFVKYCQEHGIVN-ILDLTEVDRCLQARGSEVAQDSSVE

Alignment 11
Sequence 1:
Sequence 2: Allergen Mus m 1, Sequence: P02762
Sequence identity: 22.78 (41/180)
Sequence 1 -MKALLLAVGLSLITVLQAQDPPASGED--TMAMSGKWYLKAMITD-RET
           ----LLL--GL-L--V--A------G---------G-W-------D-RE-
Sequence 2 MKMLLLLCLGLTLVCV-HAEEASSTGRNFNVEKINGEWHTIILASDKREK

Sequence 1 SWKKPELVTPMT-LTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKY
           ---------------VLE---L-----------C-E------KT-----Y
Sequence 2 IEDNGNFRLFLEQIHVLEN-SLVLKFHTVRDEECSELSMVADKTEKAGEY

Sequence 1 T-TYGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEA
           --TY-G-----I--T------------E--GE------L-GR-P------
Sequence 2 SVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDI

Sequence 1 LENFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV
           -E-F-------G---E-I--------C----------
Sequence 2 KERFAQLCEEHGILRENIIDLSNANRCLQARE-----

Alignment 12
Sequence 1:
Sequence 2: Allergen Mus m 1.0102, Sequence: AAA39768
Sequence identity: 22.78 (41/180)
Sequence 1 -MKALLLAVGLSLITVLQAQDPPASGED--TMAMSGKWYLKAMITD-RET
           ----LLL--GL-L--V--A------G---------G-W-------D-RE-
Sequence 2 MKMLLLLCLGLTLVCV-HAEEASSTGRNFNVEKINGEWHTIILASDKREK

Sequence 1 SWKKPELVTPMT-LTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKY
           ---------------VLE---L-----------C-E------KT-----Y
Sequence 2 IEDNGNFRLFLEQIHVLEK-SLVLKFHTVRDEECSELSMVADKTEKAGEY

Sequence 1 T-TYGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEA
           --TY-G-----I--T------------E--GE------L-GR-P------
Sequence 2 SVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDI

Sequence 1 LENFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV
           -E-F-------G---E-I--------C----------
Sequence 2 KERFAKLCEEHGILRENIIDLSNANRCLQARE-----

Alignment 13
Sequence 1:
Sequence 2: Allergen Bos d 5, Sequence: AAA30411
Sequence identity: 21.67 (39/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRET---S
           --------------------------------G-WY--AM----------
Sequence 2 ---------------------------IQKVAGTWYSLAMAASDISLLDA

Sequence 1 WKKPELVTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPK--KY
           ---P--V----L-----G-L--------N--C-----I-EKT--P---K-
Sequence 2 QSAPLRVYVEELKPTPEGDLEILLQKWENDECAQKKIIAEKTKIPAVFKI

Sequence 1 TTYGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEAL
           -------V-----T--K----F--E-----EQ--------R-PE---EAL
Sequence 2 DALNENKVLVLD-TDYKKYLLFCMENSAEPEQSLVCQCLVRTPEVDDEAL

Sequence 1 ENFREFLRAKGFNQEI-FSPKQ-SDTCPPGTDQEPEV
           E-F---L-A--------F-P-Q----C----------
Sequence 2 EKFDKALKALPMHIRLSFNPTQLEEQCHI--------

Alignment 14
Sequence 1:
Sequence 2: Allergen Ory c 4.0101, Sequence: U6C8D6
Sequence identity: 21.67 (39/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITD-RETSWK
           -----------------------S-------SG-WY------D-RE----
Sequence 2 -----------ILICAPKRGDAHSHSEVSQISGEWYSVLLASDHREKIEE

Sequence 1 KPEL-VTPMTLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPKKYTT-
           -----V------V-----L--------NG-C-E--L----T-----YT--
Sequence 2 NGSMRVFVEYIHVWKNSSLSFKFHTPVNGKCTELFLTCDPTEDNHVYTVE

Sequence 1 YGGKRVVYIEPTEVKDHYIFYCEGEMQGEQARMAKLVGRDPESNEEALEN
           Y-G--V--I------D--IF-------GE------L-GR---------E-
Sequence 2 YDGHNVFSILDMVPDDYIIFHLINHNNGESFQLMELYGRGLDVRSDIREK

Sequence 1 FREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV
           F-------G---E-I------D-C----D-----
Sequence 2 FVQLCQERGIVEENILDLTKVDRCLYARDGGAA-

Alignment 15
Sequence 1:
Sequence 2: Allergen Phod s 1.0101, Sequence: S5ZYD3
Sequence identity: 20.00 (36/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRETSWKK
           --------------------------D-----GKW---A---D-----K-
Sequence 2 -------------------------NDYAELEGKWDTIAIAADNDAKIKE

Sequence 1 PELVTPMTLTVLE------GGNLKAETTLLTNGQCKEVELILEKTSEPKK
           -----P--L-V-E------------------N-QC-----I--K------
Sequence 2 E---GPLRLYVRELYCNEDCSEMEVTFYVNANNQCSKTTVIGYKQADGTY

Sequence 1 YTTY-GGKRV--VYIEPTEVKDHYIFYCEG-EMQGEQARMAKLVGRDPES
           -T---G--R---VY--P--------F--------G--------VG-----
Sequence 2 RTQFEGDNRFQPVYATPENI----VFTSKNVDRAGQETNLIFVVGKSQPL

Sequence 1 NEEALENFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV
           --E--E---EF--------E-I------DTCP---------
Sequence 2 TPEQHEKLVEFAHENNIPEENIHNVLATDTCPK--------

Alignment 16
Sequence 1:
Sequence 2: Allergen Cav p 3.0101, Sequence: CAX62130
Sequence identity: 21.11 (38/180)
Sequence 1 MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITD--RETSW
           M--LLLA----L----Q--DP-----------G-W-------D-------
Sequence 2 MQILLLALTIGLAYAHQTLDPSE-------INGQWHTISIAADNVEKIGE

Sequence 1 KKPELVTPMTLTVLEG-GNLKAETTLLTNGQCKEVELILEKTSEPKKYTT
           --P-------L----G--N----------G-C--------K------Y--
Sequence 2 GGPLRGYFHNLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVA

Sequence 1 -YGGKRVVYIEPTEVKDHYIFYCEG-EMQGEQARMAKLVGRDPESNEEAL
           -Y-G------------D---FY-------G----M---V-R-----EE--
Sequence 2 QYSGTNHFEVIGKK-EDAIAFYNHNTDETGKETKMIVVVARRDSLTEEEQ

Sequence 1 ENFREFLRAKGFNQE-IFSPKQSDTCPPGTDQEPEV
           ----E----KG-----I------DTC----------
Sequence 2 QKLQEVAGEKGIPKDNIRYFRERDTCAQ--------