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SDAP - All Allergens

Go to: SDAP All allergens		Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc		Submit new allergen information to SDAP
Last Updated: Nov 1, 2021
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use. Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Der f 21.0101

Sequence ALL21_DERFA

Full FASTA alignment

Sequence name:
Query sequence:
MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD

No Allergen Sequence Link in
SwissProt/NCBI/PIR View Sequence Sequence
Length bit score E score
1 Der f 21.0101 B2GM84 Go! 136 180.4 1.5e-47
2 Der p 21.0101 ABC73706 Go! 140 132.3 4.6e-33
3 Lep d 5.0102 AAQ73493 Go! 171 76.9 2.7e-16
4 Lep d 5.0103 AAQ73494 Go! 169 76.5 3.6e-16
5 Lep d 5.0101 Q9U5P2 Go! 110 74.7 7.8e-16
6 Blo t 5 O96870 Go! 134 74.9 8.5e-16
7 Blo t 21.0101 ABH06348 Go! 129 73.6 1.9e-15
8 Blo t 21.0101 ABH06344 Go! 129 73.4 2.2e-15
9 Blo t 21.0101 ABH06347 Go! 129 73.4 2.2e-15
10 Blo t 21.0101 ABH06350 Go! 129 72.4 4.5e-15
11 Blo t 21.0101 ABH06346 Go! 129 72.4 4.5e-15
12 Der f 5.0101 ABO84970 Go! 132 63.6 2.1e-12
13 Der p 5.0102 P14004 Go! 132 59.0 5.2e-11
14 Der p 5.0101 CAA35692 Go! 148 59.1 5.5e-11
15 Der p 5.0102 AAB32842 Go! 132 58.6 6.9e-11

Alignment made with FASTA 3.45
As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous.

Alignment 1
Sequence 1:
Sequence 2: Allergen Der f 21.0101, Sequence: B2GM84
Sequence identity: 100.00 (136/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
Sequence 2 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
Sequence 2 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
Sequence 2 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD

Alignment 2
Sequence 1:
Sequence 2: Allergen Der p 21.0101, Sequence: ABC73706
Sequence identity: 72.06 (98/136)
Sequence 1 MKFII--FCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIE
           MKFII--F-AIVMA--VSGFIV----ED-WR-AFD---MEE-E-K-DQ-E
Sequence 2 MKFIITLFAAIVMAAAVSGFIVGDKKEDEWRMAFDRLMMEELETKIDQVE

Sequence 1 HGLLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRT
           -GLL-LSEQYKELEKTKSKELKEQILRELTI-EN---GALKF---EAKRT
Sequence 2 KGLLHLSEQYKELEKTKSKELKEQILRELTIGENFMKGALKFFEMEAKRT

Sequence 1 DLNMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD--
           DLNMFERYN-E-A---I--L-K-L-ELAKKVKAV--D---
Sequence 2 DLNMFERYNYEFALESIKLLIKKLDELAKKVKAVNPDEYY

Alignment 3
Sequence 1:
Sequence 2: Allergen Lep d 5.0102, Sequence: AAQ73493
Sequence identity: 41.91 (57/136)
Sequence 1 ------------------------------------MKFIIFCAIVMAVS
           ---------------------------------------------V-AV-
Sequence 2 MTGVKTHLEHELKRTDLNFLEKFNLDEITATLNVLTKELTEVQKHVKAVE

Sequence 1 VSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHGLLMLSEQYKELEKT
           -----V-----D--RN-FD--L----EE-----E--L--LS-Q--ELEK-
Sequence 2 SDEVDVAIPNPDEFRNEFDRLLIHMTEEQFAKLEQALAHLSHQVTELEKS

Sequence 1 KSKELKEQILRELTIAENYLRGALKFMQQEAKRTDLNMFERYNFETAVST
           KSKELK-QILRE--I-------A------E-KR-DLN--E--NFE-A-ST
Sequence 2 KSKELKAQILREISIGLDFIDSAKGHFERELKRADLNLAEKFNFESALST

Sequence 1 IEILVKDLAELAKKVKAVKSDD
           ---L-KDL--LA-KVKA-----
Sequence 2 GAVLHKDLTALATKVKAIETK-

Alignment 4
Sequence 1:
Sequence 2: Allergen Lep d 5.0103, Sequence: AAQ73494
Sequence identity: 40.44 (55/136)
Sequence 1 ----------------------------------MKFIIFCAIVMAVSVS
           ------------------------------------------------V-
Sequence 2 MTGVKTHLQHELKRTDLNFLEKFNLDEITAPLNVLTKELTEVQKHVKAVE

Sequence 1 GFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHGLLMLSEQYKELEKTKS
           ---V-----D--RN-FD--L----EE-----E--L--LS-Q--ELEK-KS
Sequence 2 SDEVAIPNPDEFRNEFDRLLIHMTEEQFAKLEQALAHLSHQVTELEKSKS

Sequence 1 KELKEQILRELTIAENYLRGALKFMQQEAKRTDLNMFERYNFETAVSTIE
           KELK-QILRE--I-------A------E-KR-DLN--E--NFE-A-ST--
Sequence 2 KELKAQILREISIGLDFIDSAKGHFERELKRADLNLAEKFNFESALSTGA

Sequence 1 ILVKDLAELAKKVKAVKSDD
           -L-KDL--LA-KVKA-----
Sequence 2 VLHKDLTALATKVKAIETK-

Alignment 5
Sequence 1:
Sequence 2: Allergen Lep d 5.0101, Sequence: Q9U5P2
Sequence identity: 38.97 (53/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           -------------------------D--RN-FD--L----EE-----E--
Sequence 2 -------------------------DDFRNEFDRLLIHMTEEQFAKLEQA

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           L--LS-Q--ELEK-KSKELK-QILRE--I-------A------E-KR-DL
Sequence 2 LAHLSHQVTELEKSKSKELKAQILREISIGLDFIDSAKGHFERELKRADL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           N--E--NFE-A-ST---L-KDL--LA-KVKA-----
Sequence 2 NLAEKFNFESALSTGAVLHKDLTALATKVKAIETK-

Alignment 6
Sequence 1:
Sequence 2: Allergen Blo t 5, Sequence: O96870
Sequence identity: 41.18 (56/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           MKF-I------A-SV----------D--RN-FDH-L-E---------EH-
Sequence 2 MKFAIVLIACFAASVLA-QEHKPKKDDFRNEFDHLLIEQANHAIEKGEHQ

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           LL-L--Q--EL---KSKEL-E-I-REL--------GA------E-KRTDL
Sequence 2 LLYLQHQLDELNENKSKELQEKIIRELDVVCAMIEGAQGALERELKRTDL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           N--ER-N-E-A-----IL-KDL-E---KVK------
Sequence 2 NILERFNYEEAQTLSKILLKDLKETEQKVKDIQTQ-

Alignment 7
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06348
Sequence identity: 37.50 (51/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           MKFII--A---AV------------D--R--FDHM-----------IE--
Sequence 2 MKFIIALAALIAVACALPV----SNDNFRHEFDHMIINTATQRFHEIEKF

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           LL--------LEKT--K--K---LRELT--E----G-----Q-E-KRTDL
Sequence 2 LLHITHEVDDLEKTGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRTDL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           ---E--NFE-A--T---L-KDL--L-K-V-------
Sequence 2 DLLEKFNFEAALATGDLLLKDLKALQKRVQDSE---

Alignment 8
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06344
Sequence identity: 37.50 (51/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           MKFII--A---AV------------D--R--FDHM-----------IE--
Sequence 2 MKFIIALAALIAVACALPV----SNDNFRHEFDHMIVNTATQRFHEIEKF

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           LL--------LEKT--K--K---LRELT--E----G-----Q-E-KRTDL
Sequence 2 LLHITHEVDDLEKTGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRTDL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           ---E--NFE-A--T---L-KDL--L-K-V-------
Sequence 2 DLLEKFNFEAALATGDLLLKDLKALQKRVQDSE---

Alignment 9
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06347
Sequence identity: 37.50 (51/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           MKFII--A---AV------------D--R--FDHM-----------IE--
Sequence 2 MKFIIALAALIAVACALPV----SNDNFRHEFDHMIVNAATQRFHEIEKF

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           LL--------LEKT--K--K---LRELT--E----G-----Q-E-KRTDL
Sequence 2 LLHITHEVDDLEKTGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRTDL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           ---E--NFE-A--T---L-KDL--L-K-V-------
Sequence 2 DLLEKFNFEAALATGDLLLKDLKALQKRVQDSE---

Alignment 10
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06350
Sequence identity: 36.76 (50/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           MKFII--A---AV------------D--R--FDHM-----------IE--
Sequence 2 MKFIIALAALIAVACALPV----SNDNFRHEFDHMIVNTATQRFHEIEKF

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           LL--------LE-T--K--K---LRELT--E----G-----Q-E-KRTDL
Sequence 2 LLHITHEVDDLEETGNKDEKARLLRELTVSEAFIEGSRGYFQRELKRTDL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           ---E--NFE-A--T---L-KDL--L-K-V-------
Sequence 2 DLLEKFNFEAALATGDLLLKDLKALQKRVQDSE---

Alignment 11
Sequence 1:
Sequence 2: Allergen Blo t 21.0101, Sequence: ABH06346
Sequence identity: 37.50 (51/136)
Sequence 1 MKFIIFCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIEHG
           MKFII--A---AV------------D--R--FDHM-----------IE--
Sequence 2 MKFIIALAALIAVACALPV----SNDNFRHEFDHMIVNTATQRFHEIEKF

Sequence 1 LLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRTDL
           LL--------LEKT--K--K---LRELT--E----G-----Q-E-KRTDL
Sequence 2 LLHITHEVDDLEKTGNKDEKARPLRELTVSEAFIEGSRGYFQRELKRTDL

Sequence 1 NMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           ---E--NFE-A--T---L-KDL--L-K-V-------
Sequence 2 DLLEKFNFEAALATGDLLLKDLKALQKRVQDSE---

Alignment 12
Sequence 1:
Sequence 2: Allergen Der f 5.0101, Sequence: ABO84970
Sequence identity: 38.24 (52/136)
Sequence 1 MKFIIFCAI--VMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIE
           MKFII--A------V-VSG--------D---N-FD--LM----E-M---E
Sequence 2 MKFIIAIAVCTLAVVCVSG---EPKKHD-YQNEFDFLLMQRIHEQMRKGE

Sequence 1 HGLLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRT
           --LL-L--Q----E----KE-KEQIL-E---------G---------KRT
Sequence 2 EALLHLQHQINTFEENPTKEMKEQILGEMDTIIALIDGVRGVLNRLMKRT

Sequence 1 DLNMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           DL--FERYN-E-A----EIL--DL------VK------
Sequence 2 DLDIFERYNVEIALKSNEILERDLKKEEQRVKKIEV--

Alignment 13
Sequence 1:
Sequence 2: Allergen Der p 5.0102, Sequence: P14004
Sequence identity: 33.09 (45/136)
Sequence 1 MKFII--FCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIE
           MKFII--F-A------VSG-----D------N-FD--LME---E-----E
Sequence 2 MKFIIAFFVATLAVMTVSGE----DKKHDYQNEFDFLLMERIHEQIKKGE

Sequence 1 HGLLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRT
           --L--L-EQ----E----KE-K--I--E---------G----------R-
Sequence 2 LALFYLQEQINHFEEKPTKEMKDKIVAEMDTIIAMIDGVRGVLDRLMQRK

Sequence 1 DLNMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           DL--FE-YN-E-A-----IL--DL------VK------
Sequence 2 DLDIFEQYNLEMAKKSGDILERDLKKEEARVKKIEV--

Alignment 14
Sequence 1:
Sequence 2: Allergen Der p 5.0101, Sequence: CAA35692
Sequence identity: 33.09 (45/136)
Sequence 1 ----------------MKFII--FCAIVMAVSVSGFIVDVDTEDKWRNAF
           ----------------MKFII--F-A------VSG-----D------N-F
Sequence 2 LFLENKDPKPLKKISIMKFIIAFFVATLAVMTVSGE----DKKHDYQNEF

Sequence 1 DHMLMEEFEEKMDQIEHGLLMLSEQYKELEKTKSKELKEQILRELTIAEN
           D--LME---E-----E--L--L-EQ----E----KE-K--I--E------
Sequence 2 DFLLMERIHEQIKKGELALFYLQEQINHFEEKPTKEMKDKIVAEMDTIIA

Sequence 1 YLRGALKFMQQEAKRTDLNMFERYNFETAVSTIEILVKDLAELAKKVKAV
           ---G----------R-DL--FE-YN-E-A-----IL--DL------VK--
Sequence 2 MIDGVRGVLDRLMQRKDLDIFEQYNLEMAKKSGDILERDLKKEEARVKKI

Sequence 1 KSDD
           ----
Sequence 2 EV--

Alignment 15
Sequence 1:
Sequence 2: Allergen Der p 5.0102, Sequence: AAB32842
Sequence identity: 33.09 (45/136)
Sequence 1 MKFII--FCAIVMAVSVSGFIVDVDTEDKWRNAFDHMLMEEFEEKMDQIE
           MKFII--F-A------VSG-----D------N-FD--LME---E-----E
Sequence 2 MKFIIAFFVATLAVMTVSGE----DKKHDYQNEFDFLLMERIHEQIKKGE

Sequence 1 HGLLMLSEQYKELEKTKSKELKEQILRELTIAENYLRGALKFMQQEAKRT
           --L--L-EQ----E----KE-K--I--E---------G----------R-
Sequence 2 LALFYLQEQINHFEAKPTKEMKDKIVAEMDTIIAMIDGVRGVLDRLMQRK

Sequence 1 DLNMFERYNFETAVSTIEILVKDLAELAKKVKAVKSDD
           DL--FE-YN-E-A-----IL--DL------VK------
Sequence 2 DLDIFEQYNLEMAKKSGDILERDLKKEEARVKKIEV--