SDAP - Structural Database of Allergenic Proteins



<AllerML_Allergen>
 <AllerML_Allergen_Name>Ara h 1</AllerML_Allergen_Name>
 <AllerML_SDAP_ID>324</AllerML_SDAP_ID>
 <AllerML_Organism>
  <AllerML_Systematic_Name>Arachis hypogaea</AllerML_Systematic_Name>
  <AllerML_Common_Name>peanut</AllerML_Common_Name>
 </AllerML_Organism>
 <AllerML_Comment>Vicilin; Clone P17
</AllerML_Comment>
 <AllerML_References>
  <AllerML_Reference>
   <AllerML_Reference_PubMed>7560062</AllerML_Reference_PubMed>
  </AllerML_Reference>
  <AllerML_Reference>
   <AllerML_Reference_PubMed>10998264</AllerML_Reference_PubMed>
  </AllerML_Reference>
 </AllerML_References>
 <AllerML_Protein>
  <AllerML_UniProt>
   <AllerML_UniProt_Accession>P43237</AllerML_UniProt_Accession>
  </AllerML_UniProt>
  <AllerML_UniProt>
   <AllerML_UniProt_Accession>P43238</AllerML_UniProt_Accession>
  </AllerML_UniProt>
 </AllerML_Protein>
  <AllerML_Epitopes>
   <AllerML_Epitope_Set>
   <AllerML_Epitope_Type>IgE</AllerML_Epitope_Type>
   <AllerML_Epitope_Position>25-34</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>AKSSPYQKKT</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
AKSSPYQKKT
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>48-57</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>QEPDDLKQKA</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
QEPDDLKQKA
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>65-74</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>LEYDPRLVYD</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
LEYDPRLVYD
Mutation: C71L
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>89-98</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>GERTRGRQPG</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
GERTRGRQPG
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>97-106</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>PGDYDDDRRQ</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
PGDYDDDRRQ
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>107-116</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>PRREEGGRWG</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
PRREEGGRWG
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>123-132</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>REREEDWRQP</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
REREEDWRQP
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>134-143</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>EDWRRPSHQQ</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
EDWRRPSHQQ
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>143-152</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>QPRKIRPEGR</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
QPRKIRPEGR
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>294-303</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>TPGQFEDFFP</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
TPGQFEDFFP
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>311-320</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>SYLQEFSRNT</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
SYLQEFSRNT
Mutation: G315E
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>325-334</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>FNAEFNEIRR</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
FNAEFNEIRR
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>344-353</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>EQEERGQRRW</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:

EQEERGQRRW
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>393-402</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>DITNPINLRE</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
DITNPINLRE
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>409-418</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>NNFGKLFEVK</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
NNFGKLFEVK
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>498-507</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>RRYTARLKEG</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
RRYTARLKEG
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>525-534</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>ELHLLGFGIN</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
ELHLLGFGIN
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>539-548</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>HRIFLAGDKD</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
HRIFLAGDKD
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>551-560</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>IDQIEKQAKD</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
IDQIEKQAKD
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>559-568</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>KDLAFPGSGE</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
KDLAFPGSGE
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>578-587</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>KESHFVSARP</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>When altered, amino acids shown in red lead to loss of IgE binding:
KESHFVSARP
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>281-298</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>QNLRVAKISMPVNTPGQF</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>The 4A8 MAb bound linear peptides 18, 29, 33 and 34:
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>446-463</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>PHFNSKAMVIVVVNKGTG</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>The 4A8 MAb bound linear peptides 18, 29, 33 and 34:
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>506-523</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>EGDVFIMPAAHPVAINAS</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>The 4A8 MAb bound linear peptides 18, 29, 33 and 34:
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>521-538</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>ASSELHLLGFGINAENN</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>The 4A8 MAb bound linear peptides 18, 29, 33 and 34:
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>236-253</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>LVIQQGQATVTVANGNNR</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>The 13A4 MAb bound linear peptides 15, 28 and 29 
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>431-448</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>MMLTCVEIKEGALMLPHF</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>The 13A4 MAb bound linear peptides 15, 28 and 29 
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Position>446-463</AllerML_Epitope_Position>
   <AllerML_Epitope_Sequence>PHFNSKAMVIVVVNKGTG</AllerML_Epitope_Sequence>
   <AllerML_Epitope_Comment>The 13A4 MAb bound linear peptides 15, 28 and 29
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
</AllerML_Epitope_Comment>
   <AllerML_Epitope_Reference>
   </AllerML_Epitope_Reference>
   </AllerML_Epitope_Set>
  </AllerML_Epitopes>
</AllerML_Allergen>