The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology


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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP


Input Sequence

APSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQ
THQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDP
LKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNLKA
LREKVLGLPAIKAWVAKRPPTDL
Sequence Info Allergen Name Length Opt Bits Score E Value
O18598 Bla g 5 203 1383 322.1 7.3e-90
AAB72147 Bla g 5 200 1363 317.6 1.7e-88
P46436 Asc l 13.0101w 206 447 108.8 1.2e-25
P46436 Asc s 13.0101 206 447 108.8 1.2e-25
AGG10560 Tyr p 8.0101 218 278 70.2 5.3e-14
AGC56215 Der f 8.0101 197 250 63.9 3.9e-12
P46419 Der p 8 219 215 55.8 1.1e-09
Please note: Alignment made with FASTA version 36.3.8. As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous. All FASTA search sequence alignment are printed in Blast format where Query is input sequence, and Sbjct is sequence found in the database.

Sequence Alignment: 1. Allergen Name: Bla g 5 Sequence ID: O18598

 Score = 322.1 bits 1383,  Expect = 7e-90
 Identities = 203/203 100%, Positives = 203/203 100%, Gaps = 0/203 0%
Query  1    APSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQ 60
            APSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQ
Sbjct  1    APSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQ 60
Query  61   THQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDP 120
            THQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDP
Sbjct  61   THQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDP 120
Query  121  LKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNLKA 180
            LKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNLKA
Sbjct  121  LKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNLKA 180
Query  181  LREKVLGLPAIKAWVAKRPPTDL 203
            LREKVLGLPAIKAWVAKRPPTDL
Sbjct  181  LREKVLGLPAIKAWVAKRPPTDL 203

Sequence Alignment: 2. Allergen Name: Bla g 5 Sequence ID: AAB72147

 Score = 317.6 bits 1363,  Expect = 2e-88
 Identities = 200/200 100%, Positives = 200/200 100%, Gaps = 0/200 0%
Query  4    YKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQTHQ 63
            YKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQTHQ
Sbjct  1    YKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQTHQ 60
Query  64   SVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDPLKK 123
            SVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDPLKK
Sbjct  61   SVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDPLKK 120
Query  124  ETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNLKALRE 183
            ETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNLKALRE
Sbjct  121  ETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQPNLKALRE 180
Query  184  KVLGLPAIKAWVAKRPPTDL 203
            KVLGLPAIKAWVAKRPPTDL
Sbjct  181  KVLGLPAIKAWVAKRPPTDL 200

Sequence Alignment: 3. Allergen Name: Asc l 13.0101w Sequence ID: P46436

 Score = 108.8 bits 447,  Expect = 1e-25
 Identities = 80/196 40%, Positives = 113/196 57%, Gaps = 11/196 5%
Query  2    PSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQT 61
            P YKLTY  ++ LGE  R+++      FED R++  DWP LKP  PFG+ P+LE+DG+  
Sbjct  2    PQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWPALKPKTPFGQLPLLEVDGEVL 61
Query  62   HQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAI-ANYHYDA--DENSKQKKW 118
             QS AI RYLG+QFGL+GK   E  ++D I D   DF A +   +   A  +E  K+K  
Sbjct  62   AQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKEK-- 119
Query  119  DPLKKETIPYYTKKFDEVVK--ANGG--YLAAGKLTWADFYFVAILDYLNHMAKEDLVAN 174
              LK+  +P   K +  + K  A  G  Y+    +TWAD+     L     +   D+++ 
Sbjct  120  -VLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIP-DFLSG 177
Query  175  QPNLKALREKVLGLPAIKAWVAKRPPT 201
            +  LK   E V  LP IK W+A+RP T
Sbjct  178  HLQLKKYIEHVRELPNIKKWIAERPKT 204

Sequence Alignment: 4. Allergen Name: Asc s 13.0101 Sequence ID: P46436

 Score = 108.8 bits 447,  Expect = 1e-25
 Identities = 80/196 40%, Positives = 113/196 57%, Gaps = 11/196 5%
Query  2    PSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSMPFGKTPVLEIDGKQT 61
            P YKLTY  ++ LGE  R+++      FED R++  DWP LKP  PFG+ P+LE+DG+  
Sbjct  2    PQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWPALKPKTPFGQLPLLEVDGEVL 61
Query  62   HQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAI-ANYHYDA--DENSKQKKW 118
             QS AI RYLG+QFGL+GK   E  ++D I D   DF A +   +   A  +E  K+K  
Sbjct  62   AQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKEK-- 119
Query  119  DPLKKETIPYYTKKFDEVVK--ANGG--YLAAGKLTWADFYFVAILDYLNHMAKEDLVAN 174
              LK+  +P   K +  + K  A  G  Y+    +TWAD+     L     +   D+++ 
Sbjct  120  -VLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIP-DFLSG 177
Query  175  QPNLKALREKVLGLPAIKAWVAKRPPT 201
            +  LK   E V  LP IK W+A+RP T
Sbjct  178  HLQLKKYIEHVRELPNIKKWIAERPKT 204

Sequence Alignment: 5. Allergen Name: Tyr p 8.0101 Sequence ID: AGG10560

 Score = 70.2 bits 278,  Expect = 5e-14
 Identities = 58/188 30%, Positives = 107/188 56%, Gaps = 16/188 8%
Query  6    LTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGD------WPNLKPSM--PFGKTPVLEID 57
            L Y  ++ L +PIR+LL+Y + D+ED R+Q G       W   K ++   F   P   ID
Sbjct  7    LGYWDIRGLAQPIRLLLAYLDVDYEDKRYQLGANFDRSAWLTEKFNLGLDFPNLPYY-ID 65
Query  58   GK-QTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQK 116
            G  +  Q++AI RY+G+++ L+G ++ E L + ++   + D   +++   YD   N+ + 
Sbjct  66   GNVKLSQTLAILRYIGRKYKLTGANEPEELRVSLVEQQVVDGNQSLSRVAYDP--NADKL 123
Query  117  KWDPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQP 176
            K D LK  T+P   K++   +  N  ++A   +T+ DF++   L  L+ +  E +     
Sbjct  124  KPDFLK--TLPDSVKQLSHFL-GNSPFVAGTSITYVDFWLYEYLVKLSVLVPE-VFGQFD 179
Query  177  NLKALREKVLGLPAIKAWVAKRPP 200
            NLK + E++  LP +  ++  + P
Sbjct  180  NLKKFVERIESLPRVSVYIKAQQP 203

Sequence Alignment: 6. Allergen Name: Der f 8.0101 Sequence ID: AGC56215

 Score = 63.9 bits 250,  Expect = 4e-12
 Identities = 60/173 34%, Positives = 95/173 54%, Gaps = 18/173 10%
Query  21   LLSYGEKDFEDYRFQEG------DWPNLKPSM--PFGKTPVLEIDGK-QTHQSVAISRYL 71
            +L+Y   D+ D R+  G      +W N K ++   F   P   +DG  +  QS+AI RYL
Sbjct  1    MLAYAGVDYVDKRYNIGPNFDRSEWLNEKFNLGLDFPNLPYY-MDGDVKITQSMAILRYL 59
Query  72   GKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQKKWDPLKKETIPYYTK 131
             +++ + G ++ E L I M      D   A+    YD   N +  + D LK  T+P   K
Sbjct  60   ARKYNMDGTNEQERLRISMAEQQTHDMFMAMVRICYD--PNMENLRVDYLK--TLPDSLK 115
Query  132  KFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQ-PNLKALREKVLGLPA 190
              ++ + AN  Y+A  K+++ADFY+   L  +  M  E  V  Q  NLK + E++  LP 
Sbjct  116  LMEKFL-ANHDYIAGSKISYADFYLYEYLCRMKVMVPE--VYGQFENLKKFVERIESLPR 172
Query  191  IKAWVAKRPPT 201
            I  ++ K+ PT
Sbjct  173  IAEYIKKQKPT 183

Sequence Alignment: 7. Allergen Name: Der p 8 Sequence ID: P46419

 Score = 55.8 bits 215,  Expect = 1e-09
 Identities = 62/188 32%, Positives = 99/188 52%, Gaps = 18/188 9%
Query  6    LTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPS----------MPFGKTPVLE 55
            L Y  ++   +PIR+LL+Y   DF D R+Q G  P++  S          + F   P   
Sbjct  6    LGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPYY- 64
Query  56   IDGK-QTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSK 114
            IDG  +  Q+ AI RYLG+++ L+G +D E + I M      D  AA+    YDA  N  
Sbjct  65   IDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDA--NCD 122
Query  115  QKKWDPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVAN 174
            + K D LK  ++P   K   + V     ++A   +++ DF +   L ++  M  E +   
Sbjct  123  KLKPDYLK--SLPDCLKLMSKFV-GEHAFIAGANISYVDFNLYEYLCHVKVMVPE-VFGQ 178
Query  175  QPNLKALREKVLGLPAIKAWVAKRPP 200
              NLK   E++  LP +  ++ K+ P
Sbjct  179  FENLKRYVERMESLPRVSDYIKKQQP 204

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