The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology


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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP


Input Sequence

MATKASLSIKGFALLVSVLVAVPTRVQSIGVCYGMLGNNLPPPSEVVSLYKSNNIARMRL
YDPNQAALQALRNSNIQVLLDVPRSDVQSLASNPSAAGDWIRRNVVAYWPSVSFRYIAVG
NELIPGSDLAQYILPAMRNIYNALSSAGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQ
AYLSPIVQFLASNGAPLLVNVYPYFSYTGNPGQISLPYALFTASGVVVQDGRFSYQNLFD
AIVDAVFAALERVGGANVAVVVSESGWPSAGGGAEASTSNARTYNQNLIRHVGGGTPRRP
GKEIEAYIFEMFNENQKAGGIEQNFGLFYPNKQPVYQISF
Sequence Info Allergen Name Length Opt Bits Score E Value
AAB82772 Mus a 5.0101 340 2206 509.3 9.1e-146
AAA87456 Hev b 2 374 1301 303.0 1.3e-83
AAK58515 Ole e 9 460 784 185.1 4.9e-48
Please note: Alignment made with FASTA version 36.3.8. As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous. All FASTA search sequence alignment are printed in Blast format where Query is input sequence, and Sbjct is sequence found in the database.

Sequence Alignment: 1. Allergen Name: Mus a 5.0101 Sequence ID: AAB82772

 Score = 509.3 bits 2206,  Expect = 9e-146
 Identities = 340/340 100%, Positives = 340/340 100%, Gaps = 0/340 0%
Query  1    MATKASLSIKGFALLVSVLVAVPTRVQSIGVCYGMLGNNLPPPSEVVSLYKSNNIARMRL 60
            MATKASLSIKGFALLVSVLVAVPTRVQSIGVCYGMLGNNLPPPSEVVSLYKSNNIARMRL
Sbjct  1    MATKASLSIKGFALLVSVLVAVPTRVQSIGVCYGMLGNNLPPPSEVVSLYKSNNIARMRL 60
Query  61   YDPNQAALQALRNSNIQVLLDVPRSDVQSLASNPSAAGDWIRRNVVAYWPSVSFRYIAVG 120
            YDPNQAALQALRNSNIQVLLDVPRSDVQSLASNPSAAGDWIRRNVVAYWPSVSFRYIAVG
Sbjct  61   YDPNQAALQALRNSNIQVLLDVPRSDVQSLASNPSAAGDWIRRNVVAYWPSVSFRYIAVG 120
Query  121  NELIPGSDLAQYILPAMRNIYNALSSAGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQ 180
            NELIPGSDLAQYILPAMRNIYNALSSAGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQ
Sbjct  121  NELIPGSDLAQYILPAMRNIYNALSSAGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQ 180
Query  181  AYLSPIVQFLASNGAPLLVNVYPYFSYTGNPGQISLPYALFTASGVVVQDGRFSYQNLFD 240
            AYLSPIVQFLASNGAPLLVNVYPYFSYTGNPGQISLPYALFTASGVVVQDGRFSYQNLFD
Sbjct  181  AYLSPIVQFLASNGAPLLVNVYPYFSYTGNPGQISLPYALFTASGVVVQDGRFSYQNLFD 240
Query  241  AIVDAVFAALERVGGANVAVVVSESGWPSAGGGAEASTSNARTYNQNLIRHVGGGTPRRP 300
            AIVDAVFAALERVGGANVAVVVSESGWPSAGGGAEASTSNARTYNQNLIRHVGGGTPRRP
Sbjct  241  AIVDAVFAALERVGGANVAVVVSESGWPSAGGGAEASTSNARTYNQNLIRHVGGGTPRRP 300
Query  301  GKEIEAYIFEMFNENQKAGGIEQNFGLFYPNKQPVYQISF 340
            GKEIEAYIFEMFNENQKAGGIEQNFGLFYPNKQPVYQISF
Sbjct  301  GKEIEAYIFEMFNENQKAGGIEQNFGLFYPNKQPVYQISF 340

Sequence Alignment: 2. Allergen Name: Hev b 2 Sequence ID: AAA87456

 Score = 303.0 bits 1301,  Expect = 1e-83
 Identities = 195/336 58%, Positives = 260/336 77%, Gaps = 8/336 2%
Query  3    TKASLSIKGFALLVSVLVAVPTRVQS--IGVCYGMLGNNLPPPSEVVSLYKSNNIARMRL 60
            T +S+  +   +L+  + A    +    +GVCYGM GNNLPP SEV++LYK +NI RMR+
Sbjct  10   TSSSFPSRTTVMLLLFFFAASVGITDAQVGVCYGMQGNNLPPVSEVIALYKKSNITRMRI 69
Query  61   YDPNQAALQALRNSNIQVLLDVPRSDVQSLASNPSAAGDWIRRNVVAYWPSVSFRYIAVG 120
            YDPN+A L+ALR SNI+++L VP SD+QSL +NPS A  W+++NV  +W SV FRYIAVG
Sbjct  70   YDPNRAVLEALRGSNIELILGVPNSDLQSL-TNPSNAKSWVQKNVRGFWSSVLFRYIAVG 128
Query  121  NELIP---GSD-LAQYILPAMRNIYNALSSAGLQNQIKVSTAVDTGVLGTSYPPSAGAFS 176
            NE+ P   G+  LAQ++LPAMRNI++A+ SAGLQ+QIKVSTA+D  ++G SYPPSAGAF 
Sbjct  129  NEISPVNRGTAWLAQFVLPAMRNIHDAIRSAGLQDQIKVSTAIDLTLVGNSYPPSAGAFR 188
Query  177  SAAQAYLSPIVQFLASNGAPLLVNVYPYFSYTGNPGQISLPYALFTASGVVVQDGRFSYQ 236
               ++YL PI+ FL+S  +PLL N+YPYF+Y  NP  ISLPYALFT+  VVV DG+  Y+
Sbjct  189  DDVRSYLDPIIGFLSSIRSPLLANIYPYFTYAYNPRDISLPYALFTSPSVVVWDGQRGYK 248
Query  237  NLFDAIVDAVFAALERVGGANVAVVVSESGWPSAGGGAEASTSNARTYNQNLIRHVGGGT 296
            NLFDA +DA+++ALER  G ++ VVVSESGWPSAG  A A+  N RTY  NLI+HV GGT
Sbjct  249  NLFDATLDALYSALERASGGSLEVVVSESGWPSAGAFA-ATFDNGRTYLSNLIQHVKGGT 307
Query  297  PRRPGKEIEAYIFEMFNENQKAGGIEQNFGLFYPNKQPVYQISF 340
            P+RP + IE Y+F MF+EN+K   +E++FGLF+P+K+P Y ++F
Sbjct  308  PKRPNRAIETYLFAMFDENKKQPEVEKHFGLFFPDKRPKYNLNF 351

Sequence Alignment: 3. Allergen Name: Ole e 9 Sequence ID: AAK58515

 Score = 185.1 bits 784,  Expect = 5e-48
 Identities = 121/312 38%, Positives = 193/312 61%, Gaps = 8/312 2%
Query  29   IGVCYGMLGNNLPPPSEVVSLYKSNNIARMRLYDPNQAALQALRNSNIQVLLDVPRSDVQ 88
            +GV YG L +NLP     V+L KS  I ++RL+    A ++A+ N+ +++++     D+ 
Sbjct  30   LGVNYGQLSDNLPSLQATVNLLKSTTIQKVRLFGAEPAVIKAFANTGVEIVIGFDNGDIP 89
Query  89   SLASNPSAAGDWIRRNVVAYWPSVSFRYIAVGNELIPGSD--LAQYILPAMRNIYNALSS 146
            +LASNP+ A  +++ NV++++P+ +   I VGNE++   D  L   +LPAM+N+ NAL++
Sbjct  90   TLASNPNVASQFVKSNVMSFYPASNIIAITVGNEVLTSGDQKLISQLLPAMQNVQNALNA 149
Query  147  AGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQAYLSPIVQFLASNGAPLLVNVYPYFS 206
            A L  ++KVST     VL  SYPPS+G F+      +  ++QF ++N AP++++ YPYF+
Sbjct  150  ASLGGKVKVSTVHAMAVLSQSYPPSSGVFNPGLGDTMKALLQFQSANDAPFMISPYPYFA 209
Query  207  YTGNPGQISLPYALFTASGVVVQDGR-FSYQNLFDAIVDAVFAALERVGGANVAVVVSES 265
            Y   P   +L + LF  +   V  G    Y N+FDA VDAV +AL  +G  ++ +VV+E+
Sbjct  210  YKNQPTPDTLAFCLFQPNAGQVDSGNGHKYTNMFDAQVDAVHSALNAMGFKDIEIVVAET 269
Query  266  GWPSAGGGAEASTS--NARTYNQNLIRHVGG--GTPRRPGKEIEAYIFEMFNENQKAGGI 321
            GWP  G   E   S  NA+ Y  NLI H+    GTP  PGK I+ Y+F +++E++K G  
Sbjct  270  GWPHGGDSNEVGPSLDNAKAYVGNLINHLKSKVGTPLMPGKSIDTYLFSLYDEDKKTGAS 329
Query  322  -EQNFGLFYPNKQPVYQISF 340
             E+ FGLF P+    Y + +
Sbjct  330  SEKYFGLFKPDGSTTYDVGL 349

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