The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology


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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP


Input Sequence

MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE
ELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLL
FCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI
Sequence Info Allergen Name Length Opt Bits Score E Value
P02754 Bos d 5 178 1163 272.1 6.3e-75
CAA32835 Bos d 5 178 1140 266.9 2.4e-73
AAA30411 Bos d 5 151 979 230.3 2.1e-62
AAS77253 Fel d 4 186 233 60.1 4.4e-11
XP_855342 Can f 6.0101 190 216 56.2 6.6e-10
S0BDX9 Cav p 6.0101 181 213 55.5 1e-09
Q95182 Equ c 1 187 210 54.8 1.7e-09
P02761 Rat n 1 181 204 53.5 4.1e-09
O18874 Can f 2 180 197 51.9 1.2e-08
ADK56160 Fel d 7.0101 180 188 49.9 5.1e-08
O18873 Can f 1 174 168 45.3 1.2e-06
AAA39768 Mus m 1.0102 180 168 45.3 1.2e-06
P02762 Mus m 1 180 166 44.8 1.7e-06
U6C8D6 Ory c 4.0101 172 133 37.3 0.00029
Q9QXU1 Mes a 1.0101 172 124 35.3 0.0012
Please note: Alignment made with FASTA version 36.3.8. As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous. All FASTA search sequence alignment are printed in Blast format where Query is input sequence, and Sbjct is sequence found in the database.

Sequence Alignment: 1. Allergen Name: Bos d 5 Sequence ID: P02754

 Score = 272.1 bits 1163,  Expect = 6e-75
 Identities = 178/178 100%, Positives = 178/178 100%, Gaps = 0/178 0%
Query  1    MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE 60
            MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE
Sbjct  1    MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE 60
Query  61   ELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLL 120
            ELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLL
Sbjct  61   ELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLL 120
Query  121  FCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI 178
            FCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI
Sbjct  121  FCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI 178

Sequence Alignment: 2. Allergen Name: Bos d 5 Sequence ID: CAA32835

 Score = 266.9 bits 1140,  Expect = 2e-73
 Identities = 175/178 98%, Positives = 175/178 98%, Gaps = 0/178 0%
Query  1    MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE 60
            MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE
Sbjct  1    MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE 60
Query  61   ELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLL 120
            ELKPTPEGDLEILLQKWEN ECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLL
Sbjct  61   ELKPTPEGDLEILLQKWENDECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLL 120
Query  121  FCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI 178
             CMENSAEPEQSL CQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI
Sbjct  121  VCMENSAEPEQSLVCQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI 178

Sequence Alignment: 3. Allergen Name: Bos d 5 Sequence ID: AAA30411

 Score = 230.3 bits 979,  Expect = 2e-62
 Identities = 149/151 98%, Positives = 149/151 98%, Gaps = 0/151 0%
Query  28   IQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWENGECAQKKI 87
            IQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWEN ECAQKKI
Sbjct  1    IQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWENDECAQKKI 60
Query  88   IAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDDE 147
            IAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSL CQCLVRTPEVDDE
Sbjct  61   IAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLVCQCLVRTPEVDDE 120
Query  148  ALEKFDKALKALPMHIRLSFNPTQLEEQCHI 178
            ALEKFDKALKALPMHIRLSFNPTQLEEQCHI
Sbjct  121  ALEKFDKALKALPMHIRLSFNPTQLEEQCHI 151

Sequence Alignment: 4. Allergen Name: Fel d 4 Sequence ID: AAS77253

 Score = 60.1 bits 233,  Expect = 4e-11
 Identities = 47/150 31%, Positives = 82/150 54%, Gaps = 6/150 4%
Query  1    MKCLLLALAL--TCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVY 58
            MK LLL L L   C  +   V ++   +DI K++G WYS+ +A SD+     ++  +RV+
Sbjct  1    MKLLLLCLGLILVCAHEEENVVRS--NIDISKISGEWYSILLA-SDVKEKIEENGSMRVF 57
Query  59   VEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKY 118
            VE +K      L  +++  ENG+C +  ++A+KTK   V+ +     N   +++T Y +Y
Sbjct  58   VEHIKALDNSSLSFVFHTKENGKCTEIFLVADKTK-DGVYTVVYDGYNVFSIVETVYDEY 116
Query  119  LLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDK 154
            +L+ + N  +       +   R P+V  +  EKF K
Sbjct  117  ILLHLLNFDKTRPFQLVEFYAREPDVSQKLKEKFVK 152

Sequence Alignment: 5. Allergen Name: Can f 6.0101 Sequence ID: XP_855342

 Score = 56.2 bits 216,  Expect = 7e-10
 Identities = 45/174 25%, Positives = 89/174 51%, Gaps = 3/174 1%
Query  1    MKCLLLALALTCGAQALIVTQTMKG-LDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYV 59
            MK LLL L L            +KG +DI K++G WYS+ +A SDI     ++  +RV+V
Sbjct  1    MKLLLLCLGLILVHAHEEENDVVKGNFDISKISGDWYSILLA-SDIKEKIEENGSMRVFV 59
Query  60   EELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYL 119
            ++++      L   ++   NG+C +  +I  KT+    + +     N   +++T Y+ Y+
Sbjct  60   KDIEVLSNSSLIFTMHTKVNGKCTKISLICNKTEKDGEYDVVHDGYNLFRIIETAYEDYI 119
Query  120  LFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQC 176
            +F + N  + ++    +   R P+V  +  EKF +  + + +     ++ TQ++ +C
Sbjct  120  IFHLNNVNQEQEFQLMELYGRKPDVSPKVKEKFVRYCQGMEIPKENILDLTQVD-RC 175

Sequence Alignment: 6. Allergen Name: Cav p 6.0101 Sequence ID: S0BDX9

 Score = 55.5 bits 213,  Expect = 1e-09
 Identities = 46/145 31%, Positives = 76/145 52%, Gaps = 10/145 6%
Query  6    LALALTCGAQALIVTQ-----TMKG-LDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYV 59
            + L L C    L+ TQ      ++G +D +K++G WY++   ASD      +   +RV+V
Sbjct  1    MKLQLLCLGLILLCTQGEGDEVVRGNFDAEKISGNWYTVK-EASDKRETIEEGGSMRVFV 59
Query  60   EELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYL 119
            E ++P  +  L   +   ENGEC Q  +I  +     V+ ++    N   V +TDYK Y 
Sbjct  60   ESIEPVKDSALSFKFWAHENGECKQISLICNRVA-EGVYAVEYDGYNVFRVAETDYKNYA 118
Query  120  LFCMENSAEPEQSLACQCLV-RTPEVDDEALEKFD 153
            +F + N  + E S+    L  R P+V  E   +F+
Sbjct  119  IFQLRNF-KAEGSFQLLELYGREPDVSGEIKTRFE 152

Sequence Alignment: 7. Allergen Name: Equ c 1 Sequence ID: Q95182

 Score = 54.8 bits 210,  Expect = 2e-09
 Identities = 44/154 28%, Positives = 78/154 50%, Gaps = 7/154 4%
Query  1    MKCLLLALAL--TCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVY 58
            MK LLL L L   C  Q       ++ +DI K++G WYS+ +A SD+     ++  +RV+
Sbjct  1    MKLLLLCLGLILVCAQQEENSDVAIRNFDISKISGEWYSIFLA-SDVKEKIEENGSMRVF 59
Query  59   VEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKI--DALNENKVLVLDTDYK 116
            V+ ++      L    Q   NGEC +  ++ +KT+   V+ +  D  N  ++  ++ D  
Sbjct  60   VDVIRALDNSSLYAEYQTKVNGECTEFPMVFDKTEEDGVYSLNYDGYNVFRISEFENDEH 119
Query  117  KYLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALK 157
              L +   +   P Q +  +   R P+V  E  E+F K ++
Sbjct  120  IILYLVNFDKDRPFQLF--EFYAREPDVSPEIKEEFVKIVQ 158

Sequence Alignment: 8. Allergen Name: Rat n 1 Sequence ID: P02761

 Score = 53.5 bits 204,  Expect = 4e-09
 Identities = 43/152 28%, Positives = 78/152 51%, Gaps = 3/152 1%
Query  4    LLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELK 63
            L L L L CG +A   + T   LD+ K+ G W+S+ +A++    ++ ++  +RV+++ + 
Sbjct  8    LCLGLTLVCG-HAEEASSTRGNLDVAKLNGDWFSIVVASNKREKIE-ENGSMRVFMQHID 65
Query  64   PTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCM 123
               E  L   ++  ENGEC +  ++A KT     + ++    N   +L TDY +Y++F +
Sbjct  66   VL-ENSLGFKFRIKENGECRELYLVAYKTPEDGEYFVEYDGGNTFTILKTDYDRYVMFHL 124
Query  124  ENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKA 158
             N    E         RT ++  +  EKF K  +A
Sbjct  125  INFKNGETFQLMVLYGRTKDLSSDIKEKFAKLCEA 159

Sequence Alignment: 9. Allergen Name: Can f 2 Sequence ID: O18874

 Score = 51.9 bits 197,  Expect = 1e-08
 Identities = 43/158 27%, Positives = 84/158 53%, Gaps = 8/158 5%
Query  1    MKCLLLA--LALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVY 58
            M+ LLL   LAL CG QA    +      +++++G W+S+A+A++   L+      +RV+
Sbjct  1    MQLLLLTVGLALICGLQAQEGNHEEPQGGLEELSGRWHSVALASNKSDLIKPWGH-FRVF 59
Query  59   VEELKPTPEGDL--EILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYK 116
            +  +    +G+L  +IL+ +  +G+C +  + A KT     F ++    N + + + D K
Sbjct  60   IHSMS-AKDGNLHGDILIPQ--DGQCEKVSLTAFKTATSNKFDLEYWGHNDLYLAEVDPK 116
Query  117  KYLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMH 162
             YL++ M N    + SL  + +VR      + L  F+   + + +H
Sbjct  117  SYLILYMINQYNDDTSLVAHLMVRDLSRQQDFLPAFESVCEDIGLH 162

Sequence Alignment: 10. Allergen Name: Fel d 7.0101 Sequence ID: ADK56160

 Score = 49.9 bits 188,  Expect = 5e-08
 Identities = 49/169 28%, Positives = 80/169 47%, Gaps = 8/169 4%
Query  1    MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE 60
            MK LLLA+ L+             G D   ++G WY  AM     +   +   P  V   
Sbjct  1    MKALLLAVGLSLITVLQAQDPPASGEDTMAMSGKWYLKAMITDRET---SWKKPELVTPM 57
Query  61   ELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLD-TDYKKYL 119
             L     G+L+       NG+C + ++I EKT  P   K       +V+ ++ T+ K + 
Sbjct  58   TLTVLEGGNLKAETTLLTNGQCKEVELILEKTSEPK--KYTTYGGKRVVYIEPTEVKDHY 115
Query  120  LFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQC 176
            +F  E   + EQ+   + + R PE ++EALE F + L+A   +  + F+P Q  + C
Sbjct  116  IFYCEGEMQGEQARMAKLVGRDPESNEEALENFREFLRAKGFNQEI-FSPKQ-SDTC 170

Sequence Alignment: 11. Allergen Name: Can f 1 Sequence ID: O18873

 Score = 45.3 bits 168,  Expect = 1e-06
 Identities = 46/151 30%, Positives = 64/151 42%, Gaps = 9/151 5%
Query  1    MKCLLLALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVE 60
            MK LLL + ++  A          G D   V+G WY  AM A      +    P  V   
Sbjct  1    MKTLLLTIGFSLIAILQAQDTPALGKDTVAVSGKWYLKAMTADQ----EVPEKPDSVTPM 56
Query  61   ELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTD--YKKY 118
             LK    G+LE  +    NG+C    ++  KT  P   K  A    +V+ +        Y
Sbjct  57   ILKAQKGGNLEAKITMLTNGQCQNITVVLHKTSEPG--KYTAYEGQRVVFIQPSPVRDHY 114
Query  119  LLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKA 158
            +L+C E      Q    + L R PE   EALE F +  +A
Sbjct  115  ILYC-EGELHGRQIRMAKLLGRDPEQSQEALEDFREFSRA 153

Sequence Alignment: 12. Allergen Name: Mus m 1.0102 Sequence ID: AAA39768

 Score = 45.3 bits 168,  Expect = 1e-06
 Identities = 37/151 24%, Positives = 77/151 50%, Gaps = 6/151 3%
Query  1    MKCLLL---ALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRV 57
            MK LLL    L L C  +A   + T + ++++K+ G W+++ +A SD       +  +R+
Sbjct  1    MKMLLLLCLGLTLVC-VHAEEASSTGRNFNVEKINGEWHTIILA-SDKREKIEDNGNFRL 58
Query  58   YVEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKK 117
            ++E++    E  L + ++   + EC++  ++A+KT+    + +     N   +  TDY  
Sbjct  59   FLEQIH-VLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDN 117
Query  118  YLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDK 154
            +L+  + N  + E         R P++  +  E+F K
Sbjct  118  FLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAK 154

Sequence Alignment: 13. Allergen Name: Mus m 1 Sequence ID: P02762

 Score = 44.8 bits 166,  Expect = 2e-06
 Identities = 36/149 24%, Positives = 76/149 51%, Gaps = 6/149 4%
Query  1    MKCLLL---ALALTCGAQALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRV 57
            MK LLL    L L C  +A   + T + ++++K+ G W+++ +A SD       +  +R+
Sbjct  1    MKMLLLLCLGLTLVC-VHAEEASSTGRNFNVEKINGEWHTIILA-SDKREKIEDNGNFRL 58
Query  58   YVEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKK 117
            ++E++    E  L + ++   + EC++  ++A+KT+    + +     N   +  TDY  
Sbjct  59   FLEQIH-VLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDN 117
Query  118  YLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKF 152
            +L+  + N  + E         R P++  +  E+F
Sbjct  118  FLMAHLINEKDGETFQLMGLYGREPDLSSDIKERF 152

Sequence Alignment: 14. Allergen Name: Ory c 4.0101 Sequence ID: U6C8D6

 Score = 37.3 bits 133,  Expect = 0.0003
 Identities = 29/125 23%, Positives = 58/125 46%, Gaps = 1/125 0%
Query  27   DIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWENGECAQKK 86
            ++ +++G WYS+ +A SD      ++  +RV+VE +       L   ++   NG+C +  
Sbjct  16   EVSQISGEWYSVLLA-SDHREKIEENGSMRVFVEYIHVWKNSSLSFKFHTPVNGKCTELF 74
Query  87   IIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDD 146
            +  + T+   V+ ++    N   +LD     Y++F + N    E     +   R  +V  
Sbjct  75   LTCDPTEDNHVYTVEYDGHNVFSILDMVPDDYIIFHLINHNNGESFQLMELYGRGLDVRS 134
Query  147  EALEKF 152
            +  EKF
Sbjct  135  DIREKF 140

Sequence Alignment: 15. Allergen Name: Mes a 1.0101 Sequence ID: Q9QXU1

 Score = 35.3 bits 124,  Expect = 0.001
 Identities = 34/84 40%, Positives = 53/84 63%, Gaps = 14/84 16%
Query  1    MKCLLLALAL--TCGA-QALIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRV 57
            +K LLLALAL  +C   Q L V+ +       +V G W+SL +AA + S + ++  PLRV
Sbjct  2    VKFLLLALALGVSCAQHQNLEVSPS-------EVDGKWHSLYIAADNKSKV-SEGGPLRV 53
Query  58   YVEELKPTPEGDLEIL--LQKWENGECAQKKIIAEKTK 93
            YV+ L+ + E     +    K EN  C + +++  K K
Sbjct  54   YVKHLECSDECQTFTIKFYTKVEN-VCQEHRVVGRKGK 90

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