The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology


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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP


Input Sequence

MRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGTGDDSFNTFFSETGSGK
HVPRAVYVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
RIRKLSDQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLTVSEITNTCFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIASIKTKRSIQFVDWCPTGFKVGINYQPP
TVVQVVIWLKYNVLFVCCPTLLPSLKLGLDWIINLI
Sequence Info Allergen Name Length Opt Bits Score E Value
QAT18644 Der p 33.0101 396 2685 618.4 1.8e-178
AIO08861 Der f 33.0101 461 2101 485.2 2.5e-138
Please note: Alignment made with FASTA version 36.3.8. As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous. All FASTA search sequence alignment are printed in Blast format where Query is input sequence, and Sbjct is sequence found in the database.

Sequence Alignment: 1. Allergen Name: Der p 33.0101 Sequence ID: QAT18644

 Score = 618.4 bits 2685,  Expect = 2e-178
 Identities = 396/396 100%, Positives = 396/396 100%, Gaps = 0/396 0%
Query  1    MRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGTGDDSFNTFFSETGSGK 60
            MRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGTGDDSFNTFFSETGSGK
Sbjct  1    MRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGTGDDSFNTFFSETGSGK 60
Query  61   HVPRAVYVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD 120
            HVPRAVYVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
Sbjct  61   HVPRAVYVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD 120
Query  121  RIRKLSDQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTA 180
            RIRKLSDQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTA
Sbjct  121  RIRKLSDQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTA 180
Query  181  VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 240
            VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
Sbjct  181  VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 240
Query  241  SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLTVSEITNTCFEPAN 300
            SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLTVSEITNTCFEPAN
Sbjct  241  SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLTVSEITNTCFEPAN 300
Query  301  QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIASIKTKRSIQFVDWCPTGFKVGINYQPP 360
            QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIASIKTKRSIQFVDWCPTGFKVGINYQPP
Sbjct  301  QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIASIKTKRSIQFVDWCPTGFKVGINYQPP 360
Query  361  TVVQVVIWLKYNVLFVCCPTLLPSLKLGLDWIINLI 396
            TVVQVVIWLKYNVLFVCCPTLLPSLKLGLDWIINLI
Sbjct  361  TVVQVVIWLKYNVLFVCCPTLLPSLKLGLDWIINLI 396

Sequence Alignment: 2. Allergen Name: Der f 33.0101 Sequence ID: AIO08861

 Score = 485.2 bits 2101,  Expect = 3e-138
 Identities = 303/363 83%, Positives = 340/363 93%, Gaps = 7/363 1%
Query  1    MRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGT-------GDDSFNTFF 53
            MRECIS+HVGQAGVQIGNACWELYCLEH IQPDGQ+   K+  T        +DSF+TFF
Sbjct  1    MRECISLHVGQAGVQIGNACWELYCLEHEIQPDGQLSPVKSTTTLSSSETISNDSFSTFF 60
Query  54   SETGSGKHVPRAVYVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKE 113
            +ETG+G+ VPR++YVDLEPTVVDEVRTG YR+LFHPEQLITGKEDAANNYARGHYT GK 
Sbjct  61   NETGNGRFVPRSIYVDLEPTVVDEVRTGEYRRLFHPEQLITGKEDAANNYARGHYTEGKT 120
Query  114  IVDLVLDRIRKLSDQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYP 173
            +++ V+ RI KL++QC+GLQGFLIFHSFGGGTGSGF+SLLMERLSV+YGKKSKLEFA+YP
Sbjct  121  LIEPVMRRIAKLAEQCSGLQGFLIFHSFGGGTGSGFSSLLMERLSVEYGKKSKLEFAIYP 180
Query  174  APQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQ 233
            AP +STAVVEPYNSILTTH TLEHSDC+FMVDNEAIYDICRRNL+IERP+Y NLNRLIGQ
Sbjct  181  APAISTAVVEPYNSILTTHNTLEHSDCSFMVDNEAIYDICRRNLNIERPSYMNLNRLIGQ 240
Query  234  IVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLTVSEITN 293
            IVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLV+YAP++S+EKAYHEQ+TV EIT 
Sbjct  241  IVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVSYAPIVSSEKAYHEQFTVPEITG 300
Query  294  TCFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIASIKTKRSIQFVDWCPTGFKV 353
            TCFEP+NQMVKC+ R+GKYMACCLLYRGDVVPKDVNAAIA+IK K +IQFV WCPTGFK+
Sbjct  301  TCFEPSNQMVKCNTRNGKYMACCLLYRGDVVPKDVNAAIAAIKAKSTIQFVQWCPTGFKI 360
Query  354  GINYQPPTVV 363
            GINY+PPTVV
Sbjct  361  GINYRPPTVV 370

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