The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology

SDAP Home Page
SDAP Overview

Search SDAP

SDAP Tools
FAO/WHO Allergenicity Test
FASTA Search in SDAP
Peptide Match
Peptide Similarity
Peptide-Protein PD Index
Aller_ML, Allergen Markup Language

About SDAP
General Information
Who Are We
Advisory Board
New Allergen Submission form

Allergy Links

Our Software Tools

Allergen Databases
WHO/IUIS Allergen Nomenclature database
FARRP Allergen Protein Database (University of Nebraska)
Allergen Database for Food Safety (ADFS)
COMPARE database
ALLFAM (Medical University of Vienna)
Allermatch (Wageninen University)
Allergome Database

Protein Databases
MMDB - Entrez
NCBI - Entrez

Protein Classification

Bioinformatics Servers
Peptide Match @ PIR
ClustalW @ EMBL - EBI

                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun ( Secure access to SDAP is available from

Allergen Info Description
Allergen ID 1566
Allergen Scientific Name Amb a 11.0101
Allergen Species - Systematic Name Ambrosia artemisiifolia
Allergen Species - Common Name short ragweed
Allergen Common source weed
Allergen Common name Asterales
Allergen Keywords Cysteine protease
Allergen IUIS (Yes=1, No=0) 1
Amb a 11.0101 - References
ID Reference
Pubmed ID: 25865353
Bouley J, Groeme R, Le Mignon M, Jain K, Chabre H, Bordas-Le Floch V, Couret MN, Bussières L, Lautrette A, Naveau M, Baron-Bodo V, Lombardi V, Mascarell L, Batard T, Nony E, Moingeon P. Identification of the cysteine protease Amb a 11 as a novel major allergen from short ragweed. J Allergy Clin Immunol. 2015 Oct;136(4):1055-64. doi: 10.1016/j.jaci.2015.03.001. Epub 2015 Apr 10. PMID: 25865353.
Amb a 11.0101 - Protein Sequences
Source Link to source
GenBank V5LU01
Amb a 11.0101 - PDB Structure
PDB Id PDB Name PDB Entry Deposition Date Experiment Type Observation
1566 308 5EGW 2016-04-27 X-ray diffraction resolution 2.7 A A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform.
1566 309 5EF4 2016-04-27 X-ray diffraction resolution 2.05 A A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform.

Amb a 11.0101 - Sequence Search :
Sequence Header Sequence
Amb a 11.0101
SDAP Sequence ID: 1344
SDAP Allergen ID: 1566
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Amb a 11.0101 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Amb a 11.0101 92.3 0.8 5EF4_A 100 364 386 23 - 386 22 - 385 0 766 Download (SI: 1344)
Amb a 11.0101 - Alphafold Theoretical Model Structure
Model Structure

Coverage Plddt
Amb a 11.0101 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
V5LU01 Click here to process the data
Amb a 11.0101 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
1344 1566 41 92 40 92 PF08246 Inhibitor_I29 Domain No_clan Cathepsin propeptide inhibitor domain (I29)
1344 1566 131 344 131 344 PF00112 Peptidase_C1 Domain CL0125 Papain family cysteine protease
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Amb a 11.0101 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
SDAP Home Page | Search SDAP | SDAP Manual | SDAP FAQ | Contact  
UTMB | Search | Directories | UTMB Map | News | Employment | Sitemap 
This site published by Surendra Negi
Copyright   2001-2023  The University of Texas Medical Branch. Please review our privacy policy and Internet guidelines.