The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP
Allergen Info Description
Allergen ID 696
Allergen Scientific Name Asp fl protease
Allergen Species - Systematic Name Aspergillus flavus
Allergen Species - Common Name
Allergen Common source fungi (moulds)
Allergen Common name Ascomycota Eurotiales
Allergen Keywords oryzin precursor, EC 3.4.21.63, alkaline serine protease
Allergen IUIS (Yes=1, No=0) 0
ID Allergen Name
Asp fl protease - References
ID Reference
No reference found!
Asp fl protease - Protein Sequences
Source Link to source
GenBank 5702208
Asp fl protease - Theoretical Model Structure
Model ID PDB file PDB Snapshot PDB Snapshot 90 PDB Snapshot 180 PDB Snapshot 270 3D PDB View
747 GetModel Model Pic Model Pic Model Pic Model Pic Click here
Asp fl protease - Sequence Search
Sequence Header Sequence
Asp fl protease
SDAP Sequence ID: 747
SDAP Allergen ID: 696
MQSIKRTLLLLGAILPAVLGAPVQETRRAAEKLPGKYIVTFKPGIDEAKIQEHTTWATNIHQRSLERRGATGGDLPVGIERNYKINKFAAYAGSFDDATIEEIRKNEDVAYVEEDQIYYLDGLTTQKSAPWGLGSISHKGQQSTDYIYDTSAGEGTYAYVVDSGVNVDHEEFEGRASKAYNAAGGQHVDSIGHGTHVSGTIAGKTYGIAKKASILSVKVFQGESSSTSVILDGFNWAANDIVSKKRTSKAAINMSLGGGYSKAFNDAVENAFEQGVLSVVAAGNENSDAGQTSPASAPDAITVAAIQKSNNRASFSNFGKVVDVFAPGQDILSAWIGSSSATNTISGTSMATPHIVGLSLYLAALENLDGPAAVTKRIEELATKDVVKDVKGSPNLLAYNGNA
View 3D Structure Click here to view 3D model structure of allergen
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Asp fl protease - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Asp fl protease 91 0.7 3F7O_A 52.669 281 403 124 - 402 3 - 281 0 259 Download (SI: 747)
Asp fl protease 91 0.68 3F7O_A 52.669 281 403 124 - 402 3 - 281 0 259 Download (SI: 747)
Asp fl protease - Alphafold Theoretical Model Structure
Model Structure
747_relaxed_rank_1_model_4.pdb


Coverage Plddt
Asp fl protease - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
5702208 Click here to process the data
Asp fl protease - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
747 696 36 120 36 121 PF05922 Inhibitor_I9 Domain CL0570 Peptidase inhibitor I9
747 696 155 374 153 395 PF00082 Peptidase_S8 Domain No_clan Subtilase family
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

Welcome

Predicted B-Cell epitope using BCEP method for Asp fl protease

Probe radius : 1.400

POLAR area/energy = 7624.78

APOLAR area/energy = 12487.57

Total area/energy = 20112.35

Number of surface atoms = 1622

Number of buried atoms = 1382

Residues Predicted with high probability (in top five patches) are: 1,2,131,138,141,142,143,139,145,181,183,184 , and medium probability (next top five patches) are : 184,185,186,187,221,144,130,205,206,148,204,210,211 . Predicted residues are shown in red and green color stick representation.

Original PDB file 4587.test.pdb
Original PDB file with surface residue only. All amino acid residue are replaced by their CB atom, in case of GLY CA atom is used. Solvent accessible surface area of each residue is stored in last column of the PDB file. 14587.test.txt
Patch drawn around the residues by patch analysis are stored in this file
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area), Col 4: Sum(Psur*Area), Col 5: Total Residue, Col 6: Interface score, Col 7: Surface Score, Col 8: Max Interface Score, Col 9: Minimum Interface Score
4587.test.tmppat
Residues predicted by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Res Number Col 4: Neigbouring Res Name, Col 5: Sum(Pint*Area). Col 6: Sum(PSur*Area), Col 7: Sum(Area), Col 8: Similar no of residue in patch (e.g CYS, CYS = 2)
4587.test.res
All residues scored by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area)/sum(Area), Col 4: Sum(Psur*Area)/sum(Area), Col 5: Total Residue
4587.test.resALL

[For BCEP predicted results, please cite our websites http://fermi.utmb.edu/ http://curie.utmb.edu/ for your future publications (Negi et al., Bioinformatics, 23, 3397-3399, 2007 , Negi et al., J. Mol. Model., 13, 1157-1167, 2007; Negi et al., J. Mol. Model., 12, 921-929, 2006)]



List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids
Peptides predicted from BepiPred method can be used to search related peptides in SDAP using PD search and Cross-React method.
Please note: BepiPred Epitopes are predicted using BepiPred webserver implemented in IEDB Analysis Resource at http://tools.iedb.org/main/bcell/
Cleck here for epitopes predicted by BepiPred method

Asp fl protease - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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