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Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 119
Allergen Scientific Name Can f 1
Allergen Species - Systematic Name Canis familiaris (Canis domesticus)
Allergen Species - Common Name dog
Allergen Common source animals
Allergen Common name
Allergen Keywords Dog 1 allergen
Allergen IUIS (Yes=1, No=0) 1
ID Allergen Name
Can f 1 - References
ID Reference
Pubmed ID: 2045611
de Groot H, Goei KG, van Swieten P, Aalberse RC, Affinity purification of a major and a minor allergen from dog extract: serologic activity of affinity-purified Can f I and of Can f I-depleted extract. J Allergy Clin Immunol. 1991 Jun;87(6):1056-65.
Pubmed ID: 9497502
Konieczny A, Morgenstern JP, Bizinkauskas CB, Lilley CH, Brauer AW, Bond JF, Aalberse RC, Wallner BP, Kasaian MT. The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: cloning and immunological characterization of the recombinant forms. Immunology. 1997 Dec;92(4):577-86.
Pubmed ID: 9497502
Konieczny A, Morgenstern JP, Bizinkauskas CB, Lilley CH, Brauer AW, Bond JF, Aalberse RC, Wallner BP, Kasaian MT. The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: cloning and immunological characterization of the recombinant forms. Immunology. 1997 Dec;92(4):577-86.
Can f 1 - Protein Sequences
Source Link to source
SwissProt O18873
Can f 1 - Theoretical Model Structure
Model ID PDB file PDB Snapshot PDB Snapshot 90 PDB Snapshot 180 PDB Snapshot 270 3D PDB View
81 GetModel Model Pic Model Pic Model Pic Model Pic Click here
Can f 1 - Sequence Search :
Sequence Header Sequence
Can f 1
SDAP Sequence ID: 81
SDAP Allergen ID: 119
MKTLLLTIGFSLIAILQAQDTPALGKDTVAVSGKWYLKAMTADQEVPEKPDSVTPMILKAQKGGNLEAKITMLTNGQCQNITVVLHKTSEPGKYTAYEGQRVVFIQPSPVRDHYILYCEGELHGRQIRMAKLLGRDPEQSQEALEDFREFSRAKGLNQEILELAQSETCSPGGQ
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Can f 1 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Can f 1 87.45 0.73 7DRU_A 97.484 159 174 16 - 174 5 - 163 0 323 Download (SI: 81)
Can f 1 - Alphafold Theoretical Model Structure
Model Structure
81_relaxed_rank_1_model_2.pdb


Coverage Plddt
Can f 1 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
O18873 Click here to process the data
Can f 1 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
81 119 32 161 32 167 PF00061 Lipocalin Domain CL0116 Lipocalin / cytosolic fatty-acid binding protein family
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Can f 1 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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