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Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 1663
Allergen Scientific Name Cuc ma 4.0101
Allergen Species - Systematic Name Cucurbita maxima
Allergen Species - Common Name Pumpkin
Allergen Common source Plant
Allergen Common name Plantae Magnoliopsida
Allergen Keywords 11S globulin
Allergen IUIS (Yes=1, No=0) 1
Cuc ma 4.0101 - References
ID Reference
Pubmed ID: 32706416
Bueno-Díaz C, Martín-Pedraza L, León L, Haroun-Díaz E, Pastor-Vargas C, Muñoz-García E, de Las Heras M, Batanero E, Cuesta-Herranz J, Villalba M. 2S albumins and 11S globulins, two storage proteins involved in pumpkin seeds allergy. Allergy. 2021 Jan;76(1):383-386. doi: 10.1111/all.14518. Epub 2020 Aug 25. PMID: 32706416.
Cuc ma 4.0101 - Protein Sequences
Source Link to source
GenBank P13744
Cuc ma 4.0101 - PDB Structure
PDB Id PDB Name PDB Entry Deposition Date Experiment Type Observation
1663 326 2E9Q 2007-01-26 X-ray diffraction resolution 2.2 A Recombinant pro-11S globulin of pumpkin
2E9Q.pdb


Cuc ma 4.0101 - Sequence Search :
Sequence Header Sequence
Cuc ma 4.0101
SDAP Sequence ID: 1430
SDAP Allergen ID: 1663
MARSSLFTFLCLAVFINGCLSQIEQQSPWEFQGSEVWQQHRYQSPRACRLENLRAQDPVRRAEAEAIFTEVWDQDNDEFQCAGVNMIRHTIRPKGLLLPGFSNAPKLIFVAQGFGIRGIAIPGCAETYQTDLRRSQSAGSAFKDQHQKIRPFREGDLLVVPAGVSHWMYNRGQSDLVLIVFADTRNVANQIDPYLRKFYLAGRPEQVERGVEEWERSSRKGSSGEKSGNIFSGFADEFLEEAFQIDGGLVRKLKGEDDERDRIVQVDEDFEVLLPEKDEEERSRGRYIESESESENGLEETICTLRLKQNIGRSVRADVFNPRGGRISTANYHTLPILRQVRLSAERGVLYSNAMVAPHYTVNSHSVMYATRGNARVQVVDNFGQSVFDGEVREGQVLMIPQNFVVIKRASDRGFEWIAFKTNDNAITNLLAGRVSQMRMLPLGVLSNMYRISREEAQRLKYGQQEMRVLSPGRSQGRRE
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Cuc ma 4.0101 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Cuc ma 4.0101 83.25 0.81 2E9Q_A 99.564 459 480 22 - 480 1 - 459 0 939 Download (SI: 1430)
Cuc ma 4.0101 - Alphafold Theoretical Model Structure
Model Structure
1430_relaxed_rank_1_model_1.pdb


Coverage Plddt
Cuc ma 4.0101 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
P13744 Click here to process the data
Cuc ma 4.0101 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
1430 1663 53 205 51 206 PF00190 Cupin_1 Domain CL0029 Cupin
1430 1663 317 457 311 458 PF00190 Cupin_1 Domain CL0029 Cupin
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Cuc ma 4.0101 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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