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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun ( Secure access to SDAP is available from

Allergen Info Description
Allergen ID 1666
Allergen Scientific Name Cup s 2.0101
Allergen Species - Systematic Name Cupressus sempervirens
Allergen Species - Common Name common cypress
Allergen Common source tree
Allergen Common name Plantae Pinopsida
Allergen Keywords Polygalacturonase
Allergen IUIS (Yes=1, No=0) 1
Cup s 2.0101 - References
ID Reference
Pubmed ID: 22287175
Shahali Y, Sutra JP, Haddad I, Vinh J, Guilloux L, Peltre G, Sénéchal H, Poncet P. Proteomics of cypress pollen allergens using double and triple one-dimensional electrophoresis. Electrophoresis. 2012 Feb;33(3):462-9. doi: 10.1002/elps.201100324. PMID: 22287175
Pubmed ID: 28439939
Shahali Y, Sutra JP, Hilger C, Swiontek K, Haddad I, Vinh J, Guilloux L, Charpin D, Sénéchal H, Poncet P. Identification of a polygalacturonase (Cup s 2) as the major CCD-bearing allergen in Cupressus sempervirens pollen. Allergy. 2017 Nov;72(11):1806-1810. doi: 10.1111/all.13191. Epub 2017 May 22. PMID: 28439939.
Cup s 2.0101 - Protein Sequences
Source Link to source
GenBank C0HKB1
Cup s 2.0101 - Sequence Search :
Sequence Header Sequence
Cup s 2.0101
SDAP Sequence ID: 1433
SDAP Allergen ID: 1666
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Cup s 2.0101 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Cup s 2.0101 57.1 0.48 1HG8_A 33.333 63 164 94 - 150 200 - 261 0.012 36.6 Download (SI: 1433)
Cup s 2.0101 - Alphafold Theoretical Model Structure
Model Structure

Coverage Plddt
Cup s 2.0101 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
C0HKB1 Click here to process the data
Cup s 2.0101 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
1433 1666 97 138 92 152 PF00295 Glyco_hydro_28 Repeat CL0268 Glycosyl hydrolases family 28
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Cup s 2.0101 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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