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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 82
Allergen Scientific Name Der f 1.0106
Allergen Species - Systematic Name Dermatophagoides farinae
Allergen Species - Common Name American house dust mite
Allergen Common source mites
Allergen Common name
Allergen Keywords cysteine protease; mite fecal allergen; EC 3.4.22; DerfI
Allergen IUIS (Yes=1, No=0) 1
Der f 1.0106 - References
ID Reference
Pubmed ID: 2021874
Dilworth RJ, Chua KY, Thomas WR, Sequence analysis of cDNA coding for a major house dust mite allergen, Der f I. lin Exp Allergy. 1991 Jan;21(1):25-32.
Pubmed ID: 3372999
Lind P, Hansen OC, Horn N. The binding of mouse hybridoma and human IgE antibodies to the major fecal allergen, Der p I, of Dermatophagoides pteronyssinus. Relative binding site location and species specificity studied by solid-phase inhibition assays with radiolabeled antigen. J Immunol. 1988 Jun 15;140(12):4256-62.
Der f 1.0106 - Protein Sequences
Source Link to source
SwissProt P16311
GenBank 7413
Der f 1.0106 - PDB Structure
PDB Id PDB Name PDB Entry Deposition Date Experiment Type Observation
82 212 3D6S 2008-05-20 X-ray diffraction resolution 2.00 A
3D6S.pdb


Der f 1.0106 - Theoretical Model Structure
Model ID PDB file PDB Snapshot PDB Snapshot 90 PDB Snapshot 180 PDB Snapshot 270 3D PDB View
108 GetModel Model Pic Model Pic Model Pic Model Pic Click here
784 GetModel Model Pic Model Pic Model Pic Model Pic Click here
Der f 1.0106 - Sequence Search :
Sequence Header Sequence
Der f 1.0106
SDAP Sequence ID: 108
SDAP Allergen ID: 82
MKFVLAIASLLVLSTVYARPASIKTFEEFKKAFNKNYATVEEEEVARKNFLESLKYVEANKGAINHLSDLSLDEFKNRYLMSAEAFEQLKTQFDLNAETSACRINSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCASQHGCHGDTIPRGIEYIQQNGVVEERSYPYVAREQRCRRPNSQHYGISNYCQIYPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGDDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQYPYVVIM
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Der f 1.0106
SDAP Sequence ID: 784
SDAP Allergen ID: 82
ETSACRINSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCASQHGCHGDTIPRGIEYIQQNGVVEERSYPYVAREQQCRRPNSQHYGISNYCQIYPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGVDYWIVRNSWDTTWGDSGYGYFQAGNNL
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Der f 1.0106 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Der f 1 96.95 0.86 5VPK_A 100 211 212 2 - 212 1 - 211 0 439 Download (SI: 784)
Der f 1 93.6 0.84 1XKG_A 81.848 303 321 19 - 321 1 - 302 0 533 Download (SI: 108)
Der f 1.0106 - Alphafold Theoretical Model Structure
Model Structure
784_relaxed_rank_1_model_2.pdb


Coverage Plddt
Der f 1.0106 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
P16311 Click here to process the data
7413 Click here to process the data
Der f 1.0106 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
108 82 109 317 109 320 PF00112 Peptidase_C1 Domain CL0125 Papain family cysteine protease
784 82 12 211 12 212 PF00112 Peptidase_C1 Domain CL0125 Papain family cysteine protease
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Der f 1.0106 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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