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Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 1697
Allergen Scientific Name Der f 4.0101
Allergen Species - Systematic Name Dermatophagoides farinae
Allergen Species - Common Name American house dust mite
Allergen Common source insects
Allergen Common name Animalia Arthropoda
Allergen Keywords Alpha-amylase
Allergen IUIS (Yes=1, No=0) 1
Der f 4.0101 - References
ID Reference
Pubmed ID: 26842967
Cui YB, Yu LL, Teng FX, Wang N, Zhou Y, Yang L, Zhang CB. Dust mite allergen Der f 4: Expression, characterization, and IgE binding in pediatric asthma. Pediatr Allergy Immunol. 2016 Jun;27(4):391-7. doi: 10.1111/pai.12544. PMID: 26842967.
Der f 4.0101 - Protein Sequences
Source Link to source
GenBank AHX03180
Der f 4.0101 - Sequence Search :
Sequence Header Sequence
Der f 4.0101
SDAP Sequence ID: 1460
SDAP Allergen ID: 1697
MLPKFFFILITVLTLLVSLFVNGDSKFSNPHFIGNRSVITHLMEWKYDDIGDECERFLGPYGYGGVQVSPVNEHAIMDGRPWYERYQPVSYDIHTRSGDEQQFRRMVQRCNKAGVRIYVDIVLNHMTGGQSGLGTNGHHYDGVAMQYPGVPFGPNDFHGHETCPTNDLEIHNYSNRIEARNCRLVGLRDLKQQSEYVKQKQVDFLNHLIDIGVAGFRSDASTHQWPDDLRSIYSRLHNLNNEFFTENSHPFIYHETIYYGGNGINSNEYTSLGRIIEFRFYKEITNVFRNNNQLRWLRNFGTEWGLVPSGDALVMIDSHDLRVGHTGQLGFNINCFEARLLKAATAFMLAWNYGIPRVMSSYFWDQIIRDGKDVNDWVGPPTDQHGNILSVHPNPDMTCNHEWICEHRWREIYNMVKFKLIAGQEPVNNWWDNGDNQIAFSRGNRAFIAINLQKNGNDHDKNLQKRLQTGLPPGIYCDIISGNLINNRCMGKSIQVDKNGLSDIYVGHDEFDAFVAYHIDARVES
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Der f 4.0101 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Der f 4.0101 94.45 0.89 1C8Q_A 47.475 495 525 36 - 523 10 - 496 0 468 Download (SI: 1460)
Der f 4.0101 - Alphafold Theoretical Model Structure
Model Structure
1460_relaxed_rank_1_model_4.pdb


Coverage Plddt
Der f 4.0101 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
AHX03180 Click here to process the data
Der f 4.0101 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
1460 1697 91 321 62 357 PF00128 Alpha-amylase Domain CL0058 Alpha amylase, catalytic domain
1460 1697 431 508 429 520 PF02806 Alpha-amylase_C Domain CL0369 Alpha amylase, C-terminal all-beta domain
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Der f 4.0101 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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