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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 94
Allergen Scientific Name Der p 2
Allergen Species - Systematic Name Dermatophagoides pteronyssinus
Allergen Species - Common Name European house dust mite
Allergen Common source mites
Allergen Common name
Allergen Keywords NPC2 family; DPX
Allergen IUIS (Yes=1, No=0) 1

Der p 2 : There are iso allergen in the table! Click on each iso-allergen for more information.

ID Allergen Name
1 Der p 2.0101
2 Der p 2.0102
3 Der p 2.0103
4 Der p 2.0104
5 Der p 2.0105
6 Der p 2.0106
7 Der p 2.0107
8 Der p 2.0108
9 Der p 2.0109
10 Der p 2.0110
11 Der p 2.0111
12 Der p 2.0112
13 Der p 2.0113
14 Der p 2.0114
15 Der p 2.0115
Der p 2 - References
ID Reference
Pubmed ID: 2341191
Chua KY, Doyle CR, Simpson RJ, Turner KJ, Stewart GA, Thomas WR, Isolation of cDNA coding for the major mite allergen Der p II by IgE plaque immunoassay. Int Arch Allergy Appl Immunol. 1990;91(2):118-23.
Pubmed ID: 11306927
Smith AM, Benjamin DC, Derewenda U, Smith WA, Thomas WR, Chapman MD, Sequence polymorphisms and antibody binding to the group 2 dust mite allergens. Int Arch Allergy Immunol. 2001 Jan-Mar;124(1-3):61-3.
Pubmed ID: 11398074
Smith AM, Benjamin DC, Hozic N, Derewenda U, Smith WA, Thomas WR, Gafvelin G, van Hage-Hamsten M, Chapman MD, The molecular basis of antigenic cross-reactivity between the group 2 mite allergens. J Allergy Clin Immunol. 2001 Jun;107(6):977-84.
Der p 2 - Protein Sequences
Source Link to source
SwissProt P49278
Der p 2 - PDB Structure
PDB Id PDB Name PDB Entry Deposition Date Experiment Type Observation
94 6 1A9V 10-APR-98 NMR, 10 structures mutant D1S
94 168 1KTJ 16-JAN-02 X-ray diffraction resolution 2.15 A
1KTJ.pdb


Der p 2 - Theoretical Model Structure
Model ID PDB file PDB Snapshot PDB Snapshot 90 PDB Snapshot 180 PDB Snapshot 270 3D PDB View
115 GetModel Model Pic Model Pic Model Pic Model Pic Click here
Der p 2 - Sequence Search :
Sequence Header Sequence
Der p 2
SDAP Sequence ID: 115
SDAP Allergen ID: 94
MMYKILCLSLLVAAVARDQVDVKDCANHEIKKVLVPGCHGSEPCIIHRGKPFQLEAVFEANQNTKTAKIEIKASIDGLEVDVPGIDPNACHYMKCPLVKGQQYDIKYTWNVPKIAPKSENVVVTVKVMGDDGVLACAIATHAKIRD
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Der p 2 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Der p 2 91.6 0.76 1A9V_A 100 128 146 19 - 146 2 - 129 0 265 Download (SI: 115)
Der p 2 - Alphafold Theoretical Model Structure
Model Structure
115_relaxed_rank_1_model_3.pdb


Coverage Plddt
Der p 2 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
P49278 Click here to process the data
Der p 2 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
115 94 20 137 19 142 PF02221 E1_DerP2_DerF2 Domain CL0532 ML domain
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Der p 2 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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