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SDAP - Structural Database of Allergenic Proteins
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SDAP is a Web server
that integrates a database of allergenic proteins with various computational
tools that can assist structural biology studies related to allergens.
SDAP is an important tool in the investigation of the cross-reactivity between known allergens,
in testing the FAO/WHO allergenicity rules for new proteins, and in
predicting the IgE-binding potential of genetically modified food proteins.
Using this Internet service through a browser, it is possible to retrieve information related to an
allergen from the most common protein sequence and structure databases (SwissProt, PIR, NCBI, PDB),
to find sequence and structural neighbors for an allergen, and to search for the presence of an epitope
other the whole collection of allergens.
Read an SDAP Overview or select a SDAP function from the left column.
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If SDAP is used in publications, please cite:
- Ivanciuc, O., Schein. C. H., and Braun, W.
SDAP: Database and Computational Tools for Allergenic Proteins.
Nucleic Acids Res. 2003. 31(1). 359-362.
[PubMed]
[Full Paper]
- Ivanciuc, O., Schein. C. H., and Braun, W.
Data Mining of Sequences and 3D Structures of Allergenic Proteins.
Bioinformatics 2002, 18(10), 1358-1364.
[PubMed]
[Full Paper]
The SDAP project is supported by
grants from the National Institute of Health (2R56AI064913),
and the U.S. Environmental Protection Agency under a STAR
Research Assistance Agreement (No. RD 834823).
Access to SDAP is available
free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Recent SDAP developments:
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