Department of Biochemistry and Molecular Biology

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SDAP - All Allergens

Go to: SDAP All allergens		Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc		Submit new allergen information to SDAP
Last Updated: February 25, 2013
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use. Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Asp f 1

Translate to AllerML

Allergen	Asp f 1
Type	fungi (moulds)
Species - Systematic Name	Ascomycota Eurotiales; Aspergillus fumigatus
Species - Common Name
Keywords	Restrictocin; Ribonuclease mitogillin; EC 3.1.27
Class	IUIS

Asp f 1 - PubMed	Reference
Reference 1	Madan T, Priyadarsiny P, Vaid M, Kamal N, Shah A, Haq W, Katti SB, Sarma PU, Use of a synthetic peptide epitope of Asp f 1, a major allergen or antigen of Aspergillus fumigatus, for improved immunodiagnosis of allergic bronchopulmonary aspergillosis. Clin Diagn Lab Immunol. 2004 May;11(3):552-8.
Reference 2	Kurup VP, Banerjee B, Murali PS, Greenberger PA, Krishnan M, Hari V, Fink JN, Immunodominant peptide epitopes of allergen, Asp f 1 from the fungus Aspergillus fumigatus. Peptides. 1998;19(9):1469-77.

Asp f 1 - Protein Sequences

Source	Link to Source	View Sequence	FASTA@SDAP	BLAST@NCBI	BLAST@ExPASy	PROSITE@PIR
SwissProt	P04389	Go!	Go!	Go!	Go!	Go!
GenBank	166486	Go!	Go!	Go!	Go!	Go!
GenBank	250902	Go!	Go!	Go!	Go!	Go!

FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Asp f 1 - Protein Sequence Properties

Protein Sequence	Protease cleavage sites PeptideCutter@ExPASy
P04389	Go!
166486	Go!
250902	Go!

PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Asp f 1 - Protein Similarity, Classification and Clustering

Protein Sequence	Superfamily	InterPro
P04389	Go!	Go!

Asp f 1 - Sequences from the Entrez Nucleotides database

Link to GenBank	View Sequence
166485	Go!
250901	Go!

Asp f 1 - PDB Structures

PDB Accession	Jmol	Deposition date	Experimental	Observation
1AQZ	View!	04-AUG-97	X-ray diffraction resolution 1.7 A	inorganic phosphate group at the active site

Asp f 1 - Epitopes

No	Epitope	Exact Match @SDAP	Peptide Similarity @SDAP	Exact Match @PIR	Position	Type	Description
1	WTCINQQLNP	Go!	Go!	Go!	30-39	IgE
2	KTNKWEDKRL	Go!	Go!	Go!	40-49	IgE
3	YNQAKAESNS	Go!	Go!	Go!	51-60	IgE	Mutation: S52N
4	DGKTGSSTPH	Go!	Go!	Go!	67-76	IgE	Mutation: Y74T
5	WFTNGYDGNG	Go!	Go!	Go!	77-86	IgE
6	GRTPIKFGKA	Go!	Go!	Go!	91-100	IgE
7	CDRPPKHSQN	Go!	Go!	Go!	102-111	IgE
8	GKDDHYLLEF	Go!	Go!	Go!	114-123	IgE
9	FPTFPDGHDY	Go!	Go!	Go!	123-132	IgE
10	PGPARVIYTY	Go!	Go!	Go!	143-152	IgE
11	VIYTYPNKVF	Go!	Go!	Go!	148-157	IgE
12	GIVAHQRGNQ	Go!	Go!	Go!	159-168	IgE
13	NQGDLRLCSH	Go!	Go!	Go!	167-176	IgE

V. P. Kurup, B. Banerjee, P. S. Murali, P. A. Greenberger, M. Krishnan, V. Hari, and J. N. Fink, Immunodominant peptide epitopes of allergen, Asp f 1 from the fungus Aspergillus fumigatus, Peptides 1998, 19, 1469-1477.