SDAP Home Page
SDAP Overview
SDAP All
SDAP Food
Use SDAP All
Search SDAP All
List SDAP All
SDAP Food
SDAP Tools
FAO/WHO Allergenicity Test
FASTA Search in SDAP
Peptide Match
Peptide Similarity
Peptide-Protein PD Index
Aller_ML, Allergen Markup Language
List SDAP
About SDAP
General Information
Manual
FAQ
Publications
Who Are We
Advisory Board
Allergy Links
Our Software Tools
MPACK
FANTOM
GETAREA
NOAH/DIAMOD
MASIA
PCPMer
InterProSurf
EpiSearch
Protein Databases
PDB
MMDB - Entrez
SWISS-PROT
NCBI - Entrez
PIR
Protein Classification
CATH
CE
FSSP
iProClass
ProtoMap
SCOP
TOPS
VAST
Bioinformatics Servers
@TOME
BLAST @ NCBI
BLAST @ PIR
FASTA @ PIR
Peptide Match @ PIR
ClustalW @ BCM
ClustalW @ EMBL - EBI
ClustalW @ PIR
Bioinformatics Tools
Cn3D
MolMol
Bioinformatics Links
Bioinformatics Links Directory
|
SDAP - All Allergens
 | Allergen Cry j 2Translate to AllerML |  |  | | Allergen | Cry j 2 | | Type | tree | | Species - Systematic Name | Pinales; Cryptomeria japonica | | Species - Common Name | Japanese cedar, sugi | | Keywords | Polygalacturonase; PG; Pectinase; EC 3.2.1.15
| | Class | IUIS |
|  |
| Cry j 2 - PubMed | Reference | | Reference 1 | Sakaguchi M, Inouye S, Taniai M, Ando S, Usui M, Matuhasi T, Identification of the second major allergen of Japanese cedar pollen. Allergy. 1990 May;45(4):309-12. | | Reference 2 | Namba M, Kurose M, Torigoe K, Hino K, Taniguchi Y, Fukuda S, Usui M, Kurimoto M. Molecular cloning of the second major allergen, Cry j II, from Japanese cedar pollen. FEBS Lett. 1994 Oct 17;353(2):124-8. | | Reference 3 | Komiyama N, Sone T, Shimizu K, Morikubo K, Kino K. cDNA cloning and expression of Cry j II the second major allergen of Japanese cedar pollen. Biochem Biophys Res Commun. 1994 Jun 15;201(2):1021-8. | | Reference 4 | Hashimoto M, Nigi H, Sakaguchi M, Inouye S, Imaoka K, Miyazawa H, Taniguchi Y, Kurimoto M, Yasueda H, Ogawa T. Sensitivity to two major allergens (Cry j I and Cry j II) in patients with Japanese cedar (Cryptomeria japonica) pollinosis. Clin Exp Allergy. 1995 Sep;25(9):848-52. | | Reference 5 | Tamura Y, Kawaguchi J, Serizawa N, Hirahara K, Shiraishi A, Nigi H, Taniguchi Y, Toda M, Inouye S, Takemori T, Sakaguchi M. Analysis of sequential immunoglobulin E-binding epitope of Japanese cedar pollen allergen (Cry j 2) in humans, monkeys and mice. Clin Exp Allergy. 2003 Feb;33(2):211-7. |
Cry j 2 - Isoallergens
Cry j 2 - Protein Sequences
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources
Cry j 2 - Protein Sequence Properties
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
Cry j 2 - Protein Similarity, Classification and Clustering
Cry j 2 - Protein Models
Cry j 2 - Pfam domains
| Sequence | Pfam sequence | Pfam family | Allergens from
this Pfam family | Pfam database | Pfam region | First amino acid | Last amino acid | | P43212 | | | | | | | | | | MPA2_CRYJA | PF00295 | Go! | Pfam A | 1 | 86 | 428 | | | | PF00295: Glycosyl hydrolases family 28
| | 506858 | | | | | | | | | | Q8H988_CRYJA | PF00295 | Go! | Pfam A | 1 | 86 | 428 | | | | PF00295: Glycosyl hydrolases family 28
|
Pfam is a database of multiple sequence alignments and hidden Markov models covering protein domains and families
Inspect MotifMate results for Cry j 2. AutoMotif contains a database of PCPMer motifs for allergens.
MotifMate home page
MotifMate summary
Browse MotifMate proteins
Browse MotifMate families
Cry j 2 - Sequences from the Entrez Nucleotides database
| Link to GenBank | View Sequence | | 506857 | Go! |
Cry j 2 - Epitopes| No | Epitope | Exact
Match
@SDAP | Peptide
Similarity
@SDAP | Exact
Match
@PIR | Position | Type | Description | | 1 | PGNKKFVVNNLFFNGPCQPHF | Go! | Go! | Go! | 96-116 | IgE |
| | 2 | GQCKWVNGREICNDRDRPTA | Go! | Go! | Go! | 166-185 | IgE | 169-KWVNGREI-176 is recognized by IgE in humans, monkeys and mice
| | 3 | SHIIYENVEMINSENPILINQFYCT | Go! | Go! | Go! | 324-348 | IgE |
| | 4 | YCTSASACQNQRSAVQIQDV | Go! | Go! | Go! | 346-365 | IgE |
|
Y. Tamura, J. Kawaguchi, N. Serizawa, K. Hirahara, A. Shiraishi, H. Nigi,
Y. Taniguchi, M. Toda, S. Inouye, T. Takemori, and M. Sakaguchi,
Analysis of sequential immunoglobulin E-binding epitope of Japanese
cedar pollen allergen (Cry j 2) in humans, monkeys and mice,
Clin. Exp. Allergy 2003, 33, 211-217.
Cry j 2 - Epitopes| No | Epitope | Exact
Match
@SDAP | Peptide
Similarity
@SDAP | Exact
Match
@PIR | Position | Type | Description | | 1 | VDGIIAAYQNPASWK | Go! | Go! | Go! | 120-134 | T-cell | recognized by 11 out of 18 individuals
| | 2 | NNRIWLQFAKLTGFT | Go! | Go! | Go! | 135-149 | T-cell | recognized by 9 out of 18 individuals
| | 3 | IIQGLKLMNSPEFHL | Go! | Go! | Go! | 195-209 | T-cell | recognized by 10 out of 18 individuals
| | 4 | ASKNFHLQKNTIGTG | Go! | Go! | Go! | 240-254 | T-cell | recognized by 12 out of 18 individuals
| | 5 | SRAEVSYVHVNGAKF | Go! | Go! | Go! | 290-304 | T-cell | recognized by 9 out of 18 individuals
| | 6 | CKDIKLSDISLKLTS | Go! | Go! | Go! | 390-404 | T-cell | recognized by 9 out of 18 individuals
| | 7 | LKLTSGKIASCLNDN | Go! | Go! | Go! | 400-414 | T-cell | recognized by 12 out of 18 individuals
| | 8 | GKIASCLNDNANGYF | Go! | Go! | Go! | 405-419 | T-cell | recognized by 11 out of 18 individuals
|
T. Sone, K. Morikubo, M. Miyahara, N. Komiyama, K. Shimizu, H. Tsunoo, and K. Kino,
T cell epitopes in Japanese cedar (Cryptomeria japonica) pollen allergens:
choice of major T cell epitopes in Cry j 1 and Cry j 2 toward design of the
peptide-based immunotherapeutics for the management of Japanese cedar pollinosis.
J. Immunol. 1998, 161, 448-457.
|
