The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology


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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP


Input Sequence

MAANVQTSSLLFLVFLLLQNFYSANSQSFLGVNYGQLSDNLPSLQATVNLLKSTTIQKVR
LFGAEPAVIKAFANTGVEIVIGFDNGDIPTLASNPNVASQFVKSNVMSFYPASNIIAITV
GNEVLTSGDQKLISQLLPAMQNVQNALNAASLGGKVKVSTVHAMAVLSQSYPPSSGVFNP
GLGDTMKALLQFQSANDAPFMISPYPYFAYKNQPTPDTLAFCLFQPNAGQVDSGNGHKYT
NMFDAQVDAVHSALNAMGFKDIEIVVAETGWPHGGDSNEVGPSLDNAKAYVGNLINHLKS
KVGTPLMPGKSIDTYLFSLYDEDKKTGASSEKYFGLFKPDGSTTYDVGLLKNTQNPTTPA
TPTPTPKAAGSWCVPKPGVSDDQLTGNINYACGQGIDCGPIQPGGACFEPNTVKAHAAYV
MNLYYQSAGRNSWNCDFSQTATLTNTNPSYGACNFPSGSN
Sequence Info Allergen Name Length Opt Bits Score E Value
AAK58515 Ole e 9 460 3064 704.7 2.5e-204
AAB82772 Mus a 5.0101 340 784 185.1 4.9e-48
AAA87456 Hev b 2 374 726 171.8 5.2e-44
AAL92578 Ole e 10 123 435 106.3 9.1e-25
P80741 Ole e 4 24 90 31.0 0.0084
Please note: Alignment made with FASTA version 36.3.8. As explained in the FASTA manual, the bit score is equivalent to the bit score reported by BLAST. A 1 bit increase in score corresponds to a 2-fold reduction in expectation, and a 10-bit increase implies 1000-fold lower expectation. Sequences with E values < 0.01 are almost always homologous. All FASTA search sequence alignment are printed in Blast format where Query is input sequence, and Sbjct is sequence found in the database.

Sequence Alignment: 1. Allergen Name: Ole e 9 Sequence ID: AAK58515

 Score = 704.7 bits 3064,  Expect = 2e-204
 Identities = 460/460 100%, Positives = 460/460 100%, Gaps = 0/460 0%
Query  1    MAANVQTSSLLFLVFLLLQNFYSANSQSFLGVNYGQLSDNLPSLQATVNLLKSTTIQKVR 60
            MAANVQTSSLLFLVFLLLQNFYSANSQSFLGVNYGQLSDNLPSLQATVNLLKSTTIQKVR
Sbjct  1    MAANVQTSSLLFLVFLLLQNFYSANSQSFLGVNYGQLSDNLPSLQATVNLLKSTTIQKVR 60
Query  61   LFGAEPAVIKAFANTGVEIVIGFDNGDIPTLASNPNVASQFVKSNVMSFYPASNIIAITV 120
            LFGAEPAVIKAFANTGVEIVIGFDNGDIPTLASNPNVASQFVKSNVMSFYPASNIIAITV
Sbjct  61   LFGAEPAVIKAFANTGVEIVIGFDNGDIPTLASNPNVASQFVKSNVMSFYPASNIIAITV 120
Query  121  GNEVLTSGDQKLISQLLPAMQNVQNALNAASLGGKVKVSTVHAMAVLSQSYPPSSGVFNP 180
            GNEVLTSGDQKLISQLLPAMQNVQNALNAASLGGKVKVSTVHAMAVLSQSYPPSSGVFNP
Sbjct  121  GNEVLTSGDQKLISQLLPAMQNVQNALNAASLGGKVKVSTVHAMAVLSQSYPPSSGVFNP 180
Query  181  GLGDTMKALLQFQSANDAPFMISPYPYFAYKNQPTPDTLAFCLFQPNAGQVDSGNGHKYT 240
            GLGDTMKALLQFQSANDAPFMISPYPYFAYKNQPTPDTLAFCLFQPNAGQVDSGNGHKYT
Sbjct  181  GLGDTMKALLQFQSANDAPFMISPYPYFAYKNQPTPDTLAFCLFQPNAGQVDSGNGHKYT 240
Query  241  NMFDAQVDAVHSALNAMGFKDIEIVVAETGWPHGGDSNEVGPSLDNAKAYVGNLINHLKS 300
            NMFDAQVDAVHSALNAMGFKDIEIVVAETGWPHGGDSNEVGPSLDNAKAYVGNLINHLKS
Sbjct  241  NMFDAQVDAVHSALNAMGFKDIEIVVAETGWPHGGDSNEVGPSLDNAKAYVGNLINHLKS 300
Query  301  KVGTPLMPGKSIDTYLFSLYDEDKKTGASSEKYFGLFKPDGSTTYDVGLLKNTQNPTTPA 360
            KVGTPLMPGKSIDTYLFSLYDEDKKTGASSEKYFGLFKPDGSTTYDVGLLKNTQNPTTPA
Sbjct  301  KVGTPLMPGKSIDTYLFSLYDEDKKTGASSEKYFGLFKPDGSTTYDVGLLKNTQNPTTPA 360
Query  361  TPTPTPKAAGSWCVPKPGVSDDQLTGNINYACGQGIDCGPIQPGGACFEPNTVKAHAAYV 420
            TPTPTPKAAGSWCVPKPGVSDDQLTGNINYACGQGIDCGPIQPGGACFEPNTVKAHAAYV
Sbjct  361  TPTPTPKAAGSWCVPKPGVSDDQLTGNINYACGQGIDCGPIQPGGACFEPNTVKAHAAYV 420
Query  421  MNLYYQSAGRNSWNCDFSQTATLTNTNPSYGACNFPSGSN 460
            MNLYYQSAGRNSWNCDFSQTATLTNTNPSYGACNFPSGSN
Sbjct  421  MNLYYQSAGRNSWNCDFSQTATLTNTNPSYGACNFPSGSN 460

Sequence Alignment: 2. Allergen Name: Mus a 5.0101 Sequence ID: AAB82772

 Score = 185.1 bits 784,  Expect = 5e-48
 Identities = 121/312 38%, Positives = 193/312 61%, Gaps = 8/312 2%
Query  30   LGVNYGQLSDNLPSLQATVNLLKSTTIQKVRLFGAEPAVIKAFANTGVEIVIGFDNGDIP 89
            +GV YG L +NLP     V+L KS  I ++RL+    A ++A+ N+ +++++     D+ 
Sbjct  29   IGVCYGMLGNNLPPPSEVVSLYKSNNIARMRLYDPNQAALQALRNSNIQVLLDVPRSDVQ 88
Query  90   TLASNPNVASQFVKSNVMSFYPASNIIAITVGNEVLTSGDQKLISQLLPAMQNVQNALNA 149
            +LASNP+ A  +++ NV++++P+ +   I VGNE++   D  L   +LPAM+N+ NAL++
Sbjct  89   SLASNPSAAGDWIRRNVVAYWPSVSFRYIAVGNELIPGSD--LAQYILPAMRNIYNALSS 146
Query  150  ASLGGKVKVSTVHAMAVLSQSYPPSSGVFNPGLGDTMKALLQFQSANDAPFMISPYPYFA 209
            A L  ++KVST     VL  SYPPS+G F+      +  ++QF ++N AP++++ YPYF+
Sbjct  147  AGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQAYLSPIVQFLASNGAPLLVNVYPYFS 206
Query  210  YKNQPTPDTLAFCLFQPNAGQVDSGNGHKYTNMFDAQVDAVHSALNAMGFKDIEIVVAET 269
            Y   P   +L + LF  +   V  G    Y N+FDA VDAV +AL  +G  ++ +VV+E+
Sbjct  207  YTGNPGQISLPYALFTASGVVVQDGR-FSYQNLFDAIVDAVFAALERVGGANVAVVVSES 265
Query  270  GWPHGGDSNEVGPSLDNAKAYVGNLINHLKSKVGTPLMPGKSIDTYLFSLYDEDKKTGAS 329
            GWP  G   E   S  NA+ Y  NLI H+    GTP  PGK I+ Y+F +++E++K G  
Sbjct  266  GWPSAGGGAEA--STSNARTYNQNLIRHVGG--GTPRRPGKEIEAYIFEMFNENQKAGGI 321
Query  330  SEKYFGLFKPDGSTTYDVGL 349
             E+ FGLF P+    Y + +
Sbjct  322  -EQNFGLFYPNKQPVYQISF 340

Sequence Alignment: 3. Allergen Name: Hev b 2 Sequence ID: AAA87456

 Score = 171.8 bits 726,  Expect = 5e-44
 Identities = 121/334 36%, Positives = 208/334 62%, Gaps = 16/334 4%
Query  8    SSLLFLVFLLLQNFYSANSQSFLGVNYGQLSDNLPSLQATVNLLKSTTIQKVRLFGAEPA 67
            +++++L+F++  +    ++Q  +GV YG   +NLP +   + L K + I ++R++    A
Sbjct  18   TTVMLLLFFFAASVGITDAQ--VGVCYGMQGNNLPPVSEVIALYKKSNITRMRIYDPNRA 75
Query  68   VIKAFANTGVEIVIGFDNGDIPTLASNPNVASQFVKSNVMSFYPASNIIAITVGNEV--L 125
            V++A+  + +E+++G  N D+ +L +NP+ A  +V+ NV  F+ +     I VGNE+  +
Sbjct  76   VLEALRGSNIELILGVPNSDLQSL-TNPSNAKSWVQKNVRGFWSSVLFRYIAVGNEISPV 134
Query  126  TSGDQKLISQLLPAMQNVQNALNAASLGGKVKVSTVHAMAVLSQSYPPSSGVFNPGLGDT 185
              G   L   +LPAM+N+++A+ +A L  ++KVST   + ++  SYPPS+G F   +   
Sbjct  135  NRGTAWLAQFVLPAMRNIHDAIRSAGLQDQIKVSTAIDLTLVGNSYPPSAGAFRDDVRSY 194
Query  186  MKALLQFQSANDAPFMISPYPYFAYKNQPTPDTLAFCLF-QPNAGQVDSGNGHKYTNMFD 244
            +  ++ F S+  +P++ + YPYF Y   P   +L + LF  P+    D   G+K  N+FD
Sbjct  195  LDPIIGFLSSIRSPLLANIYPYFTYAYNPRDISLPYALFTSPSVVVWDGQRGYK--NLFD 252
Query  245  AQVDAVHSALNAMGFKDIEIVVAETGWPHGGDSNEVGPSLDNAKAYVGNLINHLKSKVGT 304
            A +DA++SAL       +E+VV+E+GWP  G       ++DN + Y+ NLI H+K   GT
Sbjct  253  ATLDALYSALERASGGSLEVVVSESGWPSAG---AFAATFDNGRTYLSNLIQHVKG--GT 307
Query  305  PLMPGKSIDTYLFSLYDEDKKTGASSEKYFGLFKPDGSTTYDV--GLLKN 352
            P  P ++I+TYLF+++DE+KK     EK+FGLF PD    Y++  G  KN
Sbjct  308  PKRPNRAIETYLFAMFDENKKQ-PEVEKHFGLFFPDKRPKYNLNFGAEKN 356

Sequence Alignment: 4. Allergen Name: Ole e 10 Sequence ID: AAL92578

 Score = 106.3 bits 435,  Expect = 9e-25
 Identities = 59/105 56%, Positives = 77/105 73%, Gaps = 5/105 4%
Query  353  TQNPTTP--ATPTPTPKAAGS--WCVPKPGVSDDQLTGNINYACGQ-GIDCGPIQPGGAC 407
            T  P+ P  ++P P P   G+  WCVPK   +D QL  NI+Y C Q G+DCGPIQ  GAC
Sbjct  14   TPTPSVPTSSSPVPKPPTQGNKKWCVPKAEATDAQLQSNIDYVCSQSGMDCGPIQANGAC 73
Query  408  FEPNTVKAHAAYVMNLYYQSAGRNSWNCDFSQTATLTNTNPSYGACNFPS 457
            F PNTV+AHA+Y MN +YQS GRN ++CDFS T  +T+++PS G+C+F S
Sbjct  74   FNPNTVRAHASYAMNSWYQSKGRNDFDCDFSGTGAITSSDPSNGSCSFLS 123

Sequence Alignment: 5. Allergen Name: Ole e 4 Sequence ID: P80741

 Score = 31.0 bits 90,  Expect = 0.008
 Identities = 14/14 100%, Positives = 14/14 100%, Gaps = 0/14 0%
Query  311  SIDTYLFSLYDEDK 324
            SIDTYLFSLYDEDK
Sbjct  11   SIDTYLFSLYDEDK 24

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