The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology

SDAP Home Page
SDAP Overview


SDAP Tools
FAO/WHO Allergenicity Test
FASTA Search in SDAP
Peptide Match
Peptide Similarity
Peptide-Protein PD Index
Aller_ML, Allergen Markup Language

About SDAP
General Information
Who Are We
Advisory Board

Allergy Links

Our Software Tools

Allergen Databases
WHO/IUIS Allergen Nomenclature database
FARRP Allergen Protein Database (University of Nebraska)
Allergen Database for Food Safety (ADFS)
COMPARE database
ALLFAM (Medical University of Vienna)
Allermatch (Wageninen University)

Protein Databases
MMDB - Entrez
NCBI - Entrez

Protein Classification

Bioinformatics Servers
Peptide Match @ PIR
ClustalW @ EMBL - EBI

                SDAP - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (
Secure access to SDAP is available from
Allergen Info Description
Allergen ID 1550
Allergen Scientific Name Act d 12.0101
Allergen Species - Systematic Name Actinidia deliciosa
Allergen Species - Common Name Kiwi fruit
Allergen Common source foods
Allergen Common name
Allergen Keywords Cupin, 11S globulin
Allergen IUIS (Yes=1, No=0) 1
Act d 12.0101 - References
ID Reference
Pubmed ID: 25041438
irvent S, Cantó B, Gómez F, Blanca N, Cuesta-Herranz J, Canto G, Blanca M, Rodríguez R, Villalba M, Palomares O. Detailed characterization of Act d 12 and Act d 13 from kiwi seeds: implication in IgE cross-reactivity with peanut and tree nuts. Allergy. 2014 Nov;69(11):1481-8.
Pubmed ID: 24990823
Sirvent S, Cantó B, Cuesta-Herranz J, Gómez F, Blanca N, Canto G, Blanca M, Rodríguez R, Villalba M, Palomares O. Act d 12 and Act d 13: two novel, masked, relevant allergens in kiwifruit seeds. J Allergy Clin Immunol. 2014 Jun;133(6):1765-7.e4. doi: 10.1016/j.jaci.2014.01.035. Epub 2014 Mar 21. PMID: 24990823.
Act d 12.0101 - Protein Sequences
Source Link to source
GenBank C0HJF9
Act d 12.0101 - Sequence Search
Sequence Header Sequence
Act d 12.0101
SDAP Sequence ID: 1329
SDAP Allergen ID: 1550
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Expasy Blast Search
Act d 12.0101 - Alphafold Theoretical Model Structure
Model Structure

Coverage Plddt
Act d 12.0101 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
C0HJF9 Click here to process the data
Act d 12.0101 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.


Predicted B-Cell epitope using BCEP method for Act d 12.0101

Probe radius : 1.400

POLAR area/energy = 809.26

APOLAR area/energy = 1232.44

Total area/energy = 2041.70

Number of surface atoms = 96

Number of buried atoms = 12

Residues Predicted with high probability (in top five patches) are: 4,5,6,7,8,1,2 , and medium probability (next top five patches) are : 2,3,9,10,11,12,13 . Predicted residues are shown in red and green color stick representation.

Original PDB file 585.test.pdb
Original PDB file with surface residue only. All amino acid residue are replaced by their CB atom, in case of GLY CA atom is used. Solvent accessible surface area of each residue is stored in last column of the PDB file. 1585.test.txt
Patch drawn around the residues by patch analysis are stored in this file
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area), Col 4: Sum(Psur*Area), Col 5: Total Residue, Col 6: Interface score, Col 7: Surface Score, Col 8: Max Interface Score, Col 9: Minimum Interface Score
Residues predicted by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Res Number Col 4: Neigbouring Res Name, Col 5: Sum(Pint*Area). Col 6: Sum(PSur*Area), Col 7: Sum(Area), Col 8: Similar no of residue in patch (e.g CYS, CYS = 2)
All residues scored by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area)/sum(Area), Col 4: Sum(Psur*Area)/sum(Area), Col 5: Total Residue

[For BCEP predicted results, please cite our websites for your future publications (Negi et al., Bioinformatics, 23, 3397-3399, 2007 , Negi et al., J. Mol. Model., 13, 1157-1167, 2007; Negi et al., J. Mol. Model., 12, 921-929, 2006)]

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids
Peptides predicted from BepiPred method can be used to search related peptides in SDAP using PD search and Cross-React method.
Please note: BepiPred Epitopes are predicted using BepiPred webserver implemented in IEDB Analysis Resource at
Cleck here for epitopes predicted by BepiPred method

Act d 12.0101 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
SDAP Home Page | Search SDAP | SDAP Manual | SDAP FAQ | Contact  
UTMB | Search | Directories | UTMB Map | News | Employment | Sitemap 
This site published by Surendra Negi
Copyright   2001-2022  The University of Texas Medical Branch. Please review our privacy policy and Internet guidelines.