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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun ( Secure access to SDAP is available from

Allergen Info Description
Allergen ID 343
Allergen Scientific Name Ani s 1
Allergen Species - Systematic Name Anisakis simplex
Allergen Species - Common Name nematode
Allergen Common source others
Allergen Common name
Allergen Keywords excretory gland allergen
Allergen IUIS (Yes=1, No=0) 1
ID Allergen Name
Ani s 1 - References
ID Reference
Pubmed ID: 10887322
Moneo I, Caballero ML, Gomez F, Ortega E, Alonso MJ. Isolation and characterization of a major allergen from the fish parasite Anisakis simplex. J Allergy Clin Immunol. 2000 Jul;106(1 Pt 1):177-82.
Pubmed ID: 12141725
Caballero ML, Moneo I. Specific IgE determination to Ani s 1, a major allergen from Anisakis simplex, is a useful tool for diagnosis. Ann Allergy Asthma Immunol. 2002 Jul;89(1):74-7.
Pubmed ID: 14715556
Toro C, Caballero ML, Baquero M, Garcia-Samaniego J, Casado I, Rubio M, Moneo I. High prevalence of seropositivity to a major allergen of Anisakis simplex, Ani s 1, in dyspeptic patients. Clin Diagn Lab Immunol. 2004 Jan;11(1):115-8.
Pubmed ID: 15287588
Shimakura K, Miura H, Ikeda K, Ishizaki S, Nagashima Y, Shirai T, Kasuya S, Shiomi K. Purification and molecular cloning of a major allergen from Anisakis simplex. Mol Biochem Parasitol. 2004 May;135(1):69-75.
Ani s 1 - Protein Sequences
Source Link to source
GenBank 31339066
Ani s 1 - Sequence Search :
Sequence Header Sequence
Ani s 1
SDAP Sequence ID: 525
SDAP Allergen ID: 343
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Ani s 1 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Ani s 1 88.3 0.73 1DTK_A 43.86 57 194 28 - 84 5 - 55 0.000000144 47.8 Download (SI: 525)
Ani s 1 - Alphafold Theoretical Model Structure
Model Structure

Coverage Plddt
Ani s 1 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
31339066 Click here to process the data
Ani s 1 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
525 343 28 85 27 85 PF00014 Kunitz_BPTI Domain No_clan Kunitz/Bovine pancreatic trypsin inhibitor domain
525 343 92 134 91 134 PF14625 Lustrin_cystein Domain No_clan Lustrin, cysteine-rich repeated domain
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Ani s 1 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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