The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP
Allergen Info Description
Allergen ID 167
Allergen Scientific Name Asp n 14
Allergen Species - Systematic Name Aspergillus niger
Allergen Species - Common Name
Allergen Common source fungi (moulds)
Allergen Common name Ascomycota Eurotiales
Allergen Keywords beta-xylosidase
Allergen IUIS (Yes=1, No=0) 1
ID Allergen Name
Asp n 14 - References
ID Reference
Pubmed ID: 9723670
Sander I, Raulf-Heimsoth M, Siethoff C, Lohaus C, Meyer HE, Baur X, Allergy to Aspergillus-derived enzymes in the baking industry: identification of beta-xylosidase from Aspergillus niger as a new allergen (Asp n 14). J Allergy Clin Immunol. 1998 Aug;102(2):256-64
Asp n 14 - Protein Sequences
Source Link to source
GenBank 4235093
GenBank 2181180
Asp n 14 - Sequence Search
Sequence Header Sequence
Asp n 14
SDAP Sequence ID: 337
SDAP Allergen ID: 167
MAHSMSRPVAATAAALLALALPQALAQANTSYVDYNVEANPDLYPLCIETIPLSFPDCQNGPLRSHLICDESATPYDRAASLISLFTLDELIANTGNTGLGVSRLGLPAYQVWSEALHGLDRANFSDSGSYNWATSFPQPILTTAALNRTLIHQIASIISTQGRAFNNAGRYGLDVYAPNINTFRHPVWGRGQETPGEDVSLAAVYAYEYITGIQGPDPDSNLKLAATAKHYAGYDIENWHNHSRLGNDMNITQQDLSEYYTPQFHVAARDAKVHSVMCAYNAVDGVPACADSYFLQTLLRDTFGFVDHGYVSSDCDAAYNIYNPHGYASSQAAAAAEAILAGTDIDCGTTYQWHLNESITAGDLSRDDIEKGVIRLYTTLVQAGYFDSNTTKANNPYRDLTWSDVLETDAWNISYQAATQGIVLLKNSNNVLPLTEKAYPPSNTTVALIGPWANATTQLLGNYYGNAPYMISPRAAFEEAGYKVNFAEGTGISSTSTSGFAAALSAARSADVIIYAGGIDNTLEAEALDRESIAWPGNQLDLIQKLASSAGSKPLIVLQMGGGQVDSSSLKNNTNVTALLWGGYPGQSGGFALRDIITGKKNPAGRLVTTQYPASYAEEFPATDMNLRPEGDNPGQTYKWYTGEAVYEFGHGLFYTTFAESSSNTTTKEVKLNIQDILSQTHEELASITQLPVLNFTANIKNTGKLESDYTAMVFANTSDAGPAPYPVKWLVGWDRLGDVKVGETRELRVPVEVGSFARVNEDGDWVLFPGTFELALNLERKVRVKVVLEGEEEVVLKWPGKE
View 3D Structure Click here to view 3D model structure of allergen
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Asp n 14
SDAP Sequence ID: 338
SDAP Allergen ID: 167
MAHSMSRPVAATAAALLALALPQALAQANTSYVDYNIEANPDLYPLCIETIPLSFPDCQNGPLRSHLICDETATPYDRAASLISLFTLDELIANTGNTGLGVSRLGLPAYQVWSEALHGLDRANFSDSGAYNWATSFPQPILTTAALNRTLIHQIASIISTQGRAFNNAGRYGLDVYAPNINTFRHPVWGRGQETPGEDVSLAAVYAYEYITGIQGPDPESNLKLAATAKHYAGYDIENWHNHSRLGNDMNITQQDLSEYYTPQFHVAARDAKVQSVMCAYNAVNGVPACADSYFLQTLLRDTFGFVDHGYVSSDCDAAYNIYNPHGYASSQAAAAAEAILAGTDIDCGTTYQWHLNESIAAGDLSRDDIEQGVIRLYTTLVQAGYFDSNTTKANNPYRDLSWSDVLETDAWNISYQAATQGIVLLKNSNNVLPLTEKAYPPSNTTVALIGPWANATTQLLGNYYGNAPYMISPRAAFEEAGYKVNFAEGTGISSTSTSGFAAALSAAQSADVIIYAGGIDNTLEAEALDRESIAWPGNQLDLIQKLASAAGKKPLIVLQMGGGQVDSSSLKNNTNVSALLWGGYPGQSGGFALRDIITGKKNPAGRLVTTQYPASYAEEFPATDMNLRPEGDNPGQTYKWYTGEAVYEFGHGLFYTTFAESSSNTTTKEVKLNIQDILSQTHEDLASITQLPVLNFTANIRNTGKLESDYTAMVFANTSDAGPAPYPKKWLVGWDRLGEVKVGETRELRVPVEVGSFARVNEDGDWVVFPGTFELALNLERKVRVKVVLEGEEEVVLKWPGKE
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Expasy Blast Search
Asp n 14 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Asp n 14 94.85 0.92 6Q7I_A 66.108 776 804 28 - 801 2 - 762 0 1039 Download (SI: 337)
Asp n 14 94.95 0.92 6Q7I_A 65.894 777 804 28 - 801 2 - 762 0 1040 Download (SI: 338)
Asp n 14 - Alphafold Theoretical Model Structure
Model Structure
338_relaxed_rank_1_model_2.pdb


Coverage Plddt
Asp n 14 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
4235093 Click here to process the data
2181180 Click here to process the data
Asp n 14 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
337 167 134 378 103 380 PF00933 Glyco_hydro_3 Domain CL0058 Glycosyl hydrolase family 3 N terminal domain
337 167 423 656 423 656 PF01915 Glyco_hydro_3_C Domain No_clan Glycosyl hydrolase family 3 C-terminal domain
337 167 715 777 712 780 PF14310 Fn3-like Family CL0159 Fibronectin type III-like domain
338 167 134 378 103 380 PF00933 Glyco_hydro_3 Domain CL0058 Glycosyl hydrolase family 3 N terminal domain
338 167 423 656 423 656 PF01915 Glyco_hydro_3_C Domain No_clan Glycosyl hydrolase family 3 C-terminal domain
338 167 715 777 712 780 PF14310 Fn3-like Family CL0159 Fibronectin type III-like domain
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

Welcome

Predicted B-Cell epitope using BCEP method for Asp n 14

Probe radius : 1.400

POLAR area/energy = 11900.71

APOLAR area/energy = 17432.11

Total area/energy = 29332.82

Number of surface atoms = 3002

Number of buried atoms = 3158

Residues Predicted with high probability (in top five patches) are: , and medium probability (next top five patches) are : . Predicted residues are shown in red and green color stick representation.

Original PDB file 1630.test.pdb
Original PDB file with surface residue only. All amino acid residue are replaced by their CB atom, in case of GLY CA atom is used. Solvent accessible surface area of each residue is stored in last column of the PDB file. 11630.test.txt
Patch drawn around the residues by patch analysis are stored in this file
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area), Col 4: Sum(Psur*Area), Col 5: Total Residue, Col 6: Interface score, Col 7: Surface Score, Col 8: Max Interface Score, Col 9: Minimum Interface Score
1630.test.tmppat
Residues predicted by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Res Number Col 4: Neigbouring Res Name, Col 5: Sum(Pint*Area). Col 6: Sum(PSur*Area), Col 7: Sum(Area), Col 8: Similar no of residue in patch (e.g CYS, CYS = 2)
1630.test.res
All residues scored by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area)/sum(Area), Col 4: Sum(Psur*Area)/sum(Area), Col 5: Total Residue
1630.test.resALL

[For BCEP predicted results, please cite our websites http://fermi.utmb.edu/ http://curie.utmb.edu/ for your future publications (Negi et al., Bioinformatics, 23, 3397-3399, 2007 , Negi et al., J. Mol. Model., 13, 1157-1167, 2007; Negi et al., J. Mol. Model., 12, 921-929, 2006)]



List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids
Peptides predicted from BepiPred method can be used to search related peptides in SDAP using PD search and Cross-React method.
Please note: BepiPred Epitopes are predicted using BepiPred webserver implemented in IEDB Analysis Resource at http://tools.iedb.org/main/bcell/
Cleck here for epitopes predicted by BepiPred method

Asp n 14 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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