The University of Texas Medical Branch
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP
Allergen Info Description
Allergen ID 171
Allergen Scientific Name Asp o 21
Allergen Species - Systematic Name Aspergillus oryzae
Allergen Species - Common Name
Allergen Common source fungi (moulds)
Allergen Common name Ascomycota Eurotiales
Allergen Keywords TAKA-amylase A
Allergen IUIS (Yes=1, No=0) 1
ID Allergen Name
Asp o 21 - References
ID Reference
No reference found!
Asp o 21 - Protein Sequences
Source Link to source
GenBank 217823
GenBank 166531
Asp o 21 - PDB Structure
PDB Id PDB Name PDB Entry Deposition Date Experiment Type Observation
171 199 7TAA 06-OCT-97 X-ray diffraction resolution 1.98 A
7TAA.pdb


Asp o 21 - Sequence Search
Sequence Header Sequence
Asp o 21
SDAP Sequence ID: 340
SDAP Allergen ID: 171
MMVAWWSLFLYGLQVAAPALAATPADWRSQSIYFLLTDRFARTDGSTTATCNTADQKYCGGTWQGIIDKLDYIQGMGFTAIWITPVTAQLPQTTAYGDAYHGYWQQDIYSLNENYGTADDLKALSSALHERGMYLMVDVVANHMGYDGAGSSVDYSVFKPFSSQDYFHPFCFIQNYEDQTQVEYCWLGDNTVSLLDLDTTKDVVKNEWYDWVGSLVSNYSIDGLRIDTVKHVQKDFWPGYNKAAGVYCIGEVLDVDPAYTCPYQNVMDGVLNYPIYYPLLNAFKSTSGSMDDLYNMINTVKSDCPDSTLLGTFVENHDNPRFASYTNDIALAKNVAAFIILNDGIPIIYAGQEQHYAGGNDPANREATWLSGYPTDSELYKLIASANAIRNYAISKDTGFVTYKNWPIYKDDTTIAMRKGTDGSQIVTILSNKGASGDSYTLSLSGAGYTAGQQLTEVIGCTTVTVGSDGNVPVPMAGGLPRVLYPTEKLAGSKICSSS
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
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Expasy Blast Search
Asp o 21
SDAP Sequence ID: 341
SDAP Allergen ID: 171
MMVAWWSLFLYGLQVAAPALAATPADWRSQSIYFLLTDRFARTDGSTTATCNTADQKYCGGTWQGIIDKLDYIQGMGFTAIWITPVTAQLPQTTAYGDAYHGYWQQDIYSLNENYGTADDLKALSSALHERGMYLMVDVVANHMGYDGAGSSVDYSVFKPFSSQDYFHPFCLIQNYEDQTQVEDCWLGDNTVSLPDLDTTKDVVKNEWYDWVGSLVSNYSIDGLRIDTVKHVQKDFWPGYNKAAGVYCIGEVLDGDPAYTCPYQNVMDGVLNYPIYYPLLNAFKSTSGSMHDLYNMINTVKSDCPDSTLLGTFVENHDNPRFASYTNDIALAKNVAAFIILNDGIPIIYAGQEQHYAGGNDPANREATWASGYPTDSELYKLIASANAIRNYAISKDTGFVTYKNWPIYKDDTTIAMRKGTDGSQIVTILSNKGASGDSYTLSLSGAGYTAGQQLTEVIGCTTVTVGSDGNVPVPMAGGLPRVLYPTEKLAGSKICSSS
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Expasy Blast Search
Asp o 21 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Asp o 21 95.85 0.88 6XSJ_A 99.599 499 499 1 - 499 1 - 499 0 1024 Download (SI: 341)
Asp o 21 95.8 0.87 6YQ7_A 99.399 499 499 1 - 499 1 - 499 0 1019 Download (SI: 340)
Asp o 21 - Alphafold Theoretical Model Structure
Model Structure
341_relaxed_rank_1_model_2.pdb


Coverage Plddt
Asp o 21 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
217823 Click here to process the data
166531 Click here to process the data
Asp o 21 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
340 171 61 362 61 362 PF00128 Alpha-amylase Domain CL0058 Alpha amylase, catalytic domain
340 171 407 496 407 496 PF09260 A_amylase_dom_C Domain CL0369 Alpha-amylase, domain C
341 171 61 362 61 362 PF00128 Alpha-amylase Domain CL0058 Alpha amylase, catalytic domain
341 171 407 496 407 496 PF09260 A_amylase_dom_C Domain CL0369 Alpha-amylase, domain C
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

Welcome

Predicted B-Cell epitope using BCEP method for Asp o 21

Probe radius : 1.400

POLAR area/energy = 7327.20

APOLAR area/energy = 12139.24

Total area/energy = 19466.44

Number of surface atoms = 1875

Number of buried atoms = 1984

Residues Predicted with high probability (in top five patches) are: 1,2,3,4,5,6,55,56,57,58,59 , and medium probability (next top five patches) are : 59,64,67,68,69,42,43,60,62,45,44 . Predicted residues are shown in red and green color stick representation.

Original PDB file 2510.test.pdb
Original PDB file with surface residue only. All amino acid residue are replaced by their CB atom, in case of GLY CA atom is used. Solvent accessible surface area of each residue is stored in last column of the PDB file. 12510.test.txt
Patch drawn around the residues by patch analysis are stored in this file
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area), Col 4: Sum(Psur*Area), Col 5: Total Residue, Col 6: Interface score, Col 7: Surface Score, Col 8: Max Interface Score, Col 9: Minimum Interface Score
2510.test.tmppat
Residues predicted by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Res Number Col 4: Neigbouring Res Name, Col 5: Sum(Pint*Area). Col 6: Sum(PSur*Area), Col 7: Sum(Area), Col 8: Similar no of residue in patch (e.g CYS, CYS = 2)
2510.test.res
All residues scored by patch analysis are stored in this file.
How to read: Col 1: Patch No. Col 2: Center Res Name. Col 3: Sum(Pint*Area)/sum(Area), Col 4: Sum(Psur*Area)/sum(Area), Col 5: Total Residue
2510.test.resALL

[For BCEP predicted results, please cite our websites http://fermi.utmb.edu/ http://curie.utmb.edu/ for your future publications (Negi et al., Bioinformatics, 23, 3397-3399, 2007 , Negi et al., J. Mol. Model., 13, 1157-1167, 2007; Negi et al., J. Mol. Model., 12, 921-929, 2006)]



List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids
Peptides predicted from BepiPred method can be used to search related peptides in SDAP using PD search and Cross-React method.
Please note: BepiPred Epitopes are predicted using BepiPred webserver implemented in IEDB Analysis Resource at http://tools.iedb.org/main/bcell/
Cleck here for epitopes predicted by BepiPred method

Asp o 21 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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