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Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 96
Allergen Scientific Name Der p 4
Allergen Species - Systematic Name Dermatophagoides pteronyssinus
Allergen Species - Common Name European house dust mite
Allergen Common source mites
Allergen Common name
Allergen Keywords Alpha-amylase; EC 3.2.1.1
Allergen IUIS (Yes=1, No=0) 1
ID Allergen Name
Der p 4 - References
ID Reference
Pubmed ID: 1710630
Lake FR, Ward LD, Simpson RJ, Thompson PJ, Stewart GA, House dust mite-derived amylase: allergenicity and physicochemical characterization. J Allergy Clin Immunol. 1991 Jun;87(6):1035-42.
Der p 4 - Protein Sequences
Source Link to source
SwissProt P49274
GenBank 5059162
Der p 4 - Sequence Search :
Sequence Header Sequence
Der p 4
SDAP Sequence ID: 117
SDAP Allergen ID: 96
KYXNPHFIGXRSVITXLME
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Der p 4
SDAP Sequence ID: 791
SDAP Allergen ID: 96
KYHNPHFIGNRSVITHLMEWKYDDIGDECERFLGPYGYGGVQVSPVNEHAILDRRPWYERYQPVSYDIRTRSGDEQQFRRMVKRCNKAGVRIYVDIVLNHMTGAQSGKGTNGHHYDGNTLQYPGVPFGPNDFHGHESCPTQDLEIHDYTNPKEARNCRLSGLRDLKQQSEYVRQKQVDFLNHLIDIGVAGFRSDASTHQWPDDLRSIYSRLHNLNKEFFPENSQPFIYHETIYYGGNGINSNEYTSLGRIIEFRFYKEITNVFRGNNPLHWLKNFGTEWGLVPSGDALVMIDSHDLRVGHTGKLGFNINCFEGRLLKAATAFMLAWNYGVPRVMSSYFWNQIIKDGKDVNDWVGPPSDKNGNILSVHPNPDMTCNHEWICEHRWREIYNMVKFRMIAGQEPVHNWWDNGDYQIAFSRGNRAFIAINLQKNQQNLQQKLHTGLPAGTYCDIISGNLIDNKCTGKSIHVDKNGQADVYVGHDEFDAFVAYHIGARIVS
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Der p 4 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Der p 4 97.5 0.94 3VM5_A 47.295 499 496 3 - 494 2 - 497 0 479 Download (SI: 791)
Der p 4 - Alphafold Theoretical Model Structure
Model Structure
791_relaxed_rank_1_model_2.pdb


Coverage Plddt
Der p 4 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
P49274 Click here to process the data
5059162 Click here to process the data
Der p 4 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
791 96 66 263 37 331 PF00128 Alpha-amylase Domain CL0058 Alpha amylase, catalytic domain
791 96 406 481 404 491 PF02806 Alpha-amylase_C Domain CL0369 Alpha amylase, C-terminal all-beta domain
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Der p 4 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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