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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 122
Allergen Scientific Name Equ c 1
Allergen Species - Systematic Name Equus caballus
Allergen Species - Common Name domestic horse
Allergen Common source animals
Allergen Common name
Allergen Keywords lipocalin
Allergen IUIS (Yes=1, No=0) 1
ID Allergen Name
Equ c 1 - References
ID Reference
Pubmed ID: 10787420
Goubran Botros H, Poncet P, Rabillon J, Fontaine T, Laval JM, David B, Biochemical characterization and surfactant properties of horse allergens. Eur J Biochem. 2001 May;268(10):3126-36.
Pubmed ID: 8955138
Gregoire C, Rosinski-Chupin I, Rabillon J, Alzari PM, David B, Dandeu JP. cDNA cloning and sequencing reveal the major horse allergen Equ c1 to be a glycoprotein member of the lipocalin superfamily. J Biol Chem. 1996 Dec 20;271(51):32951-9.
Pubmed ID: 10787420
Lascombe MB, Gregoire C, Poncet P, Tavares GA, Rosinski-Chupin I, Rabillon J, Goubran-Botros H, Mazie JC, David B, Alzari PM. Crystal structure of the allergen Equ c 1. A dimeric lipocalin with restricted IgE-reactive epitopes. J Biol Chem. 2000 Jul 14;275(28):21572-7.
Equ c 1 - Protein Sequences
Source Link to source
SwissProt Q95182
Equ c 1 - PDB Structure
PDB Id PDB Name PDB Entry Deposition Date Experiment Type Observation
122 2 1EW3 21-APR-00 X-ray diffraction resolution 2.3 A
1EW3.pdb


Equ c 1 - Theoretical Model Structure
Model ID PDB file PDB Snapshot PDB Snapshot 90 PDB Snapshot 180 PDB Snapshot 270 3D PDB View
129 GetModel Model Pic Model Pic Model Pic Model Pic Click here
Equ c 1 - Sequence Search :
Sequence Header Sequence
Equ c 1
SDAP Sequence ID: 129
SDAP Allergen ID: 122
MKLLLLCLGLILVCAQQEENSDVAIRNFDISKISGEWYSIFLASDVKEKIEENGSMRVFVDVIRALDNSSLYAEYQTKVNGECTEFPMVFDKTEEDGVYSLNYDGYNVFRISEFENDEHIILYLVNFDKDRPFQLFEFYAREPDVSPEIKEEFVKIVQKRGIVKENIIDLTKIDRCFQLRGNGVAQA
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Equ c 1 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Equ c 1 91.55 0.82 1EW3_A 100 159 187 23 - 181 1 - 159 0 323 Download (SI: 129)
Equ c 1 - Alphafold Theoretical Model Structure
Model Structure
129_relaxed_rank_1_model_2.pdb


Coverage Plddt
Equ c 1 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
Q95182 Click here to process the data
Equ c 1 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
129 122 34 172 34 174 PF00061 Lipocalin Domain CL0116 Lipocalin / cytosolic fatty-acid binding protein family
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Equ c 1 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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