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Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology



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                SDAP 2.0 - Structural Database of Allergenic Proteins
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Werner Braun      Submit new allergen information to SDAP
  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Access to SDAP is available free of charge for Academic and non-profit use.< Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu). Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Info Description
Allergen ID 128
Allergen Scientific Name Fel d 2
Allergen Species - Systematic Name Felis domesticus
Allergen Species - Common Name cat (saliva)
Allergen Common source animals
Allergen Common name
Allergen Keywords albumin
Allergen IUIS (Yes=1, No=0) 1
ID Allergen Name
Fel d 2 - References
ID Reference
Pubmed ID: 8647469
Hilger C, Grigioni F, Hentges F, Sequence of the gene encoding cat (Felis domesticus) serum albumin. Gene. 1996 Mar 9;169(2):295-6.
Pubmed ID: 9105522
Hilger C, Kohnen M, Grigioni F, Lehners C, Hentges F, Allergic cross-reactions between cat and pig serum albumin. Study at the protein and DNA levels. Allergy. 1997 Feb;52(2):179-87.
Fel d 2 - Protein Sequences
Source Link to source
SwissProt P49064
Fel d 2 - Sequence Search :
Sequence Header Sequence
Fel d 2
SDAP Sequence ID: 140
SDAP Allergen ID: 128
MKWVTFISLLLLFSSAYSRGVTRREAHQSEIAHRFNDLGEEHFRGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKGCVADQSAANCEKSLHELLGDKLCTVASLRDKYGEMADCCEKKEPERNECFLQHKDDNPGFGQLVTPEADAMCTAFHENEQRFLGKYLYEIARRHPYFYAPELLYYAEEYKGVFTECCEAADKAACLTPKVDALREKVLASSAKERLKCASLQKFGERAFKAWSVARLSQKFPKAEFAEISKLVTDLAKIHKECCHGDLLECADDRADLAKYICENQDSISTKLKECCGKPVLEKSHCISEVERDELPADLPPLAVDFVEDKEVCKNYQEAKDVFLGTFLYEYSRRHPEYSVSLLLRLAKEYEATLEKCCATDDPPACYAHVFDEFKPLVEEPHNLVKTNCELFEKLGEYGFQNALLVRYTKKVPQVSTPTLVEVSRSLGKVGSKCCTHPEAERLSCAEDYLSVVLNRLCVLHEKTPVSERVTKCCTESLVNRRPCFSALQVDETYVPKEFSAETFTFHADLCTLPEAEKQIKKQSALVELLKHKPKATEEQLKTVMGDFGSFVDKCCAAEDKEACFAEEGPKLVAAAQAALA
View 3D Structure Click here to view 3D model structure of allergen
Fasta Search in SDAP
Blast Swissprot database search at NCBI
Blast PDB database search at NCBI
Blast NR database search at NCBI
Fel d 2 - Statistics from Alphafold ( SI is sequence id, Best template format: PDB_ChainID)
Allergen Name pLDDT Score pTM Score Best PDB template %Seq ID Align length Seq length Query Range Sequence Range E-Value Bit Score Download Model
Fel d 2 92.15 0.88 5YXE_A 100 584 608 25 - 608 1 - 584 0 1184 Download (SI: 140)
Fel d 2 - Alphafold Theoretical Model Structure
Model Structure
140_relaxed_rank_1_model_1.pdb


Coverage Plddt
Fel d 2 - Protein Sequence Properties!
Protein Sequence Protease cleavage sites PeptideCutter at ExPASy
P49064 Click here to process the data
Fel d 2 - PFAM Information
SeqID Aller ID AlnS AlnE EnvS EnvE PFAM ID Family Type Clan Description
140 128 31 202 30 202 PF00273 Serum_albumin Domain CL0282 Serum albumin family
140 128 223 394 222 394 PF00273 Serum_albumin Domain CL0282 Serum albumin family
140 128 415 592 414 592 PF00273 Serum_albumin Domain CL0282 Serum albumin family
Where: AlnS= Alignment start position, AlnE= Alignment end position, EnvS= Envelope start position, EnvE= Envelope end position.

List of B-cell epitopes predicted by BepiPred method using a window size of 9 amino acids

Cleck here for epitopes predicted by BepiPred method
Fel d 2 - Epitope Information from published data
No. Position Epitope Sequence Epitope Type View epitope Search epitope in SDAP PD search in SDAP Cross-React search
No epitope information found!
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