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Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology

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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Asp f 1

Translate to AllerML
AllergenAsp f 1
Typefungi (moulds)
Species - Systematic NameAscomycota Eurotiales; Aspergillus fumigatus
Species - Common Name 
KeywordsRestrictocin; Ribonuclease mitogillin; EC 3.1.27
ClassIUIS

Asp f 1 - PubMedReference
Reference 1Madan T, Priyadarsiny P, Vaid M, Kamal N, Shah A, Haq W, Katti SB, Sarma PU, Use of a synthetic peptide epitope of Asp f 1, a major allergen or antigen of Aspergillus fumigatus, for improved immunodiagnosis of allergic bronchopulmonary aspergillosis. Clin Diagn Lab Immunol. 2004 May;11(3):552-8.
Reference 2Kurup VP, Banerjee B, Murali PS, Greenberger PA, Krishnan M, Hari V, Fink JN, Immunodominant peptide epitopes of allergen, Asp f 1 from the fungus Aspergillus fumigatus. Peptides. 1998;19(9):1469-77.

Asp f 1 - Protein Sequences
SourceLink to SourceView SequenceFASTA@SDAPBLAST@NCBIBLAST@ExPASyPROSITE@PIR
SwissProtP04389Go!Go!Go!Go!Go!
GenBank166486Go!Go!Go!Go!Go!
GenBank250902Go!Go!Go!Go!Go!
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Asp f 1 - Protein Sequence Properties
Protein SequenceProtease cleavage sites
PeptideCutter@ExPASy
P04389Go!
166486Go!
250902Go!
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Asp f 1 - Protein Similarity, Classification and Clustering
Protein SequenceSuperfamilyInterPro
P04389Go!Go!

Asp f 1 - Sequences from the Entrez Nucleotides database
Link to GenBankView Sequence
166485Go!
250901Go!

Asp f 1 - PDB Structures
PDB AccessionJmolDeposition dateExperimentalObservation
1AQZView!04-AUG-97X-ray diffraction resolution 1.7 Ainorganic phosphate group at the active site

Asp f 1 - Epitopes
NoEpitopeExact
Match
@SDAP
Peptide
Similarity
@SDAP
Exact
Match
@PIR
PositionTypeDescription
1WTCINQQLNPGo!Go!Go!30-39IgE 
2KTNKWEDKRLGo!Go!Go!40-49IgE 
3YNQAKAESNSGo!Go!Go!51-60IgE Mutation: S52N
4DGKTGSSTPHGo!Go!Go!67-76IgE Mutation: Y74T
5WFTNGYDGNGGo!Go!Go!77-86IgE 
6GRTPIKFGKAGo!Go!Go!91-100IgE 
7CDRPPKHSQNGo!Go!Go!102-111IgE 
8GKDDHYLLEFGo!Go!Go!114-123IgE 
9FPTFPDGHDYGo!Go!Go!123-132IgE 
10PGPARVIYTYGo!Go!Go!143-152IgE 
11VIYTYPNKVFGo!Go!Go!148-157IgE 
12GIVAHQRGNQGo!Go!Go!159-168IgE 
13NQGDLRLCSHGo!Go!Go!167-176IgE 
V. P. Kurup, B. Banerjee, P. S. Murali, P. A. Greenberger, M. Krishnan, V. Hari, and J. N. Fink, Immunodominant peptide epitopes of allergen, Asp f 1 from the fungus Aspergillus fumigatus, Peptides 1998, 19, 1469-1477.


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