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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Hev b 1

Translate to AllerML
AllergenHev b 1
Typeothers
Species - Systematic NameHevea brasiliensis
Species - Common Namerubber (latex)
Keywordselongation factor; Rubber elongation factor protein (REF)
ClassIUIS

Hev b 1 - PubMedReference
Reference 1Czuppon AB, Chen Z, Rennert S, Engelke T, Meyer HE, Heber M, Baur X. The rubber elongation factor of rubber trees (Hevea brasiliensis) is the major allergen in latex. J Allergy Clin Immunol. 1993 Nov;92(5):690-7.
Reference 2Attanyaka DP, Kekwick RG, Franklin FC. Molecular cloning and nucleotide sequencing of the rubber elongation factor gene from Hevea brasiliensis. Plant Mol Biol. 1991 Jun;16(6):1079-81.
Reference 3Banerjee B, Kanitpong K, Fink JN, Zussman M, Sussman GL, Kelly KJ, Kurup VP, Unique and shared IgE epitopes of Hev b 1 and Hev b 3 in latex allergy. Mol Immunol. 2000 Aug-Sep;37(12-13):789-98.

Hev b 1 - Protein Sequences
SourceLink to SourceView SequenceFASTA@SDAPBLAST@NCBIBLAST@ExPASyPROSITE@PIR
SwissProtP15252Go!Go!Go!Go!Go!
GenBank18839Go!Go!Go!Go!Go!
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Hev b 1 - Protein Sequence Properties
Protein SequenceProtease cleavage sites
PeptideCutter@ExPASy
P15252Go!
18839Go!
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Hev b 1 - Protein Similarity, Classification and Clustering
Protein SequenceSuperfamilyInterPro
P15252Go!Go!

Hev b 1 - Epitopes
NoEpitopeExact
Match
@SDAP
Peptide
Similarity
@SDAP
Exact
Match
@PIR
PositionTypeDescription
1AEDEDNQQGQGo!Go!Go!2-11IgE 
2KYLGFVQDAAGo!Go!Go!16-25IgE Typo for residues 24 and 25 in Table 1
3YLFAKDKSGPGo!Go!Go!36-45IgE 
4LQPGVDIIEGGo!Go!Go!46-55IgE 
5AVPLYNRFSYGo!Go!Go!61-70IgE 
6YNRFSYIPNGGo!Go!Go!65-74IgE 
7IDRSLPPIVKGo!Go!Go!90-99IgE 
8KDASIQVVSAGo!Go!Go!99-108IgE 
B. Banerjee, K. Kanitpong, J. N. Fink, M. Zussman, G. L. Sussman, K. J. Kelly, and V. P. Kurup, Unique and shared IgE epitopes of Hev b 1 and Hev b 3 in latex allergy, Mol. Immunol. 2000, 37, 789-798.


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