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SDAP - All Allergens
Go to: SDAP All allergens       Go to: SDAP Food allergens
Send a comment to Ovidiu Ivanciuc      Submit new allergen information to SDAP
Last Updated: February 25, 2013  
Alphabetical listing of allergens: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Access to SDAP is available free of charge for Academic and non-profit use.
Licenses for commercial use can be obtained by contacting W. Braun (webraun@utmb.edu).
Secure access to SDAP is available from https://fermi.utmb.edu/SDAP

Allergen Der p 2

Translate to AllerML
AllergenDer p 2
Typemites
Species - Systematic NameDermatophagoides pteronyssinus
Species - Common NameEuropean house dust mite
KeywordsNPC2 family; DPX
ClassIUIS

Der p 2 - PubMedReference
Reference 1Chua KY, Doyle CR, Simpson RJ, Turner KJ, Stewart GA, Thomas WR, Isolation of cDNA coding for the major mite allergen Der p II by IgE plaque immunoassay. Int Arch Allergy Appl Immunol. 1990;91(2):118-23.
Reference 2Smith AM, Benjamin DC, Derewenda U, Smith WA, Thomas WR, Chapman MD, Sequence polymorphisms and antibody binding to the group 2 dust mite allergens. Int Arch Allergy Immunol. 2001 Jan-Mar;124(1-3):61-3.
Reference 3Smith AM, Benjamin DC, Hozic N, Derewenda U, Smith WA, Thomas WR, Gafvelin G, van Hage-Hamsten M, Chapman MD, The molecular basis of antigenic cross-reactivity between the group 2 mite allergens. J Allergy Clin Immunol. 2001 Jun;107(6):977-84.

Der p 2 - Isoallergens
NoIsoallergen
1Der p 2.0101
2Der p 2.0102
3Der p 2.0103
4Der p 2.0104
5Der p 2.0105
6Der p 2.0106
7Der p 2.0107
8Der p 2.0108
9Der p 2.0109
10Der p 2.0110
11Der p 2.0111
12Der p 2.0112
13Der p 2.0113
14Der p 2.0114
15Der p 2.0115

Der p 2 - Protein Sequences
SourceLink to SourceView SequenceFASTA@SDAPBLAST@NCBIBLAST@ExPASyPROSITE@PIR
SwissProtP49278Go!Go!Go!Go!Go!
FASTA@SDAP: FASTA search against all SDAP allergen sequences performed at SDAP
BLAST@ExPASy: BLAST search performed at the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)
PROSITE@PIR: PROSITE search performed at PIR - Protein Information Resources

Der p 2 - Protein Sequence Properties
Protein SequenceProtease cleavage sites
PeptideCutter@ExPASy
P49278Go!
PeptideCutter@ExPASy: Protease cleavage sites predicted with PeptideCutter from the Expert Protein Analysis System (ExPASy) proteomics server of the Swiss Institute of Bioinformatics (SIB)

Der p 2 - Protein Similarity, Classification and Clustering
Protein SequenceSuperfamilyInterPro
P49278Go!Go!

Der p 2 - Protein Models
3D ModelSourceLink to SourceView SequenceView AlignmentGet ModelPicturePicture+90Picture+180Picture+270Jmol
Model 115SwissProtP49278Go!Go!Go!Go!Go!Go!Go!View!
This 3D allergen model is superseded by newer PDB structures.

Der p 2 - Pfam domains
SequencePfam sequencePfam familyAllergens from
this Pfam family
Pfam databasePfam regionFirst amino acidLast amino acid
P49278       
 ALL2_DERPTPF02221Go!Pfam A118143
  PF02221: ML domain
Pfam is a database of multiple sequence alignments and hidden Markov models covering protein domains and families

Inspect MotifMate results for Der p 2. AutoMotif contains a database of PCPMer motifs for allergens.
MotifMate home page
MotifMate summary
Browse MotifMate proteins
Browse MotifMate families

Der p 2 - PDB Structures
PDB AccessionJmolDeposition dateExperimentalObservation
1A9VView!10-APR-98NMR, 10 structuresmutant D1S
1KTJView!16-JAN-02X-ray diffraction resolution 2.15 A 


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